Align Technology, Inc. Hits 52-Week Low at USD 122.00 Amidst Major Decline

Align Technology, Inc., a small-cap player in the Pharmaceuticals & Biotechnology sector, has reached a new 52-week low of USD 122.00 as of September 25, 2025. This significant decline reflects a challenging year for the company, with a one-year performance drop of 51.16%, starkly contrasting with the S&P 500's positive return of 15.79% during the same period.
The company's market capitalization stands at approximately USD 9,920 million, and it currently has a price-to-earnings (P/E) ratio of 29.00. Align Technology has not offered dividends, maintaining a 0.00% yield. Its debt-to-equity ratio is reported at -0.22, indicating a low level of debt relative to equity, while the return on equity (ROE) is at 12.39%, showcasing management efficiency.

Despite these metrics, Align Technology has faced challenges in long-term growth, with operating profit increasing at an annual rate of only 18.90% over the past five years. The stock's performance has been below par, with a notable decline in returns over the last year and underperformance compared to broader market indices.