Is Apellis Pharmaceuticals, Inc. overvalued or undervalued?

Jun 25 2025 08:34 AM IST
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As of February 25, 2021, Apellis Pharmaceuticals is rated as "risky" and overvalued, with key ratios indicating poor performance compared to peers, including a Price to Book Value of 14.76 and a year-to-date return of -44.78%, significantly lagging behind the S&P 500's 2.44%.
As of 25 February 2021, Apellis Pharmaceuticals, Inc. has moved from a grade of "does not qualify" to "risky." The company is currently considered overvalued. Key ratios include a Price to Book Value of 14.76, an EV to EBIT of -13.55, and a ROE of -135.02%.

In comparison to its peers, Apellis has a significantly lower EV to EBITDA ratio of -13.68, while United Therapeutics Corp., which is rated attractive, boasts a P/E ratio of 16.99 and an EV to EBITDA of 11.79. Additionally, Intra-Cellular Therapies, Inc. is also rated risky with a P/E of -187.76, highlighting the challenging landscape for Apellis. The company's recent stock performance has lagged behind the S&P 500, with a year-to-date return of -44.78% compared to the index's 2.44%, reinforcing the notion of overvaluation.
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