Is Axsome Therapeutics, Inc. overvalued or undervalued?

Jun 25 2025 08:38 AM IST
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As of August 9, 2022, Axsome Therapeutics, Inc. is considered overvalued and risky, with a price-to-book ratio of 103.56, an EV to EBITDA of -23.34, and a return on equity of -464.66%, contrasting sharply with healthier peers like Halozyme Therapeutics, Inc. which has a P/E ratio of 13.48.
As of 9 August 2022, the valuation grade for Axsome Therapeutics, Inc. moved from does not qualify to risky, indicating a significant shift in perception. The company is currently considered overvalued. Key ratios highlight this concern, with a price-to-book value of 103.56 and an EV to EBITDA of -23.34, both suggesting excessive valuation relative to its financial performance. Additionally, the return on equity (ROE) stands at a staggering -464.66%, reflecting severe losses.

In comparison to peers, Axsome's valuation metrics are starkly unfavorable. For instance, Halozyme Therapeutics, Inc. is rated fair with a P/E ratio of 13.48 and an EV to EBITDA of 10.76, showcasing a much healthier financial standing. The stark contrast in these ratios underscores Axsome's overvaluation in the market. Despite a strong performance over the past year with a 33.07% return compared to the S&P 500's 10.26%, the underlying financial fundamentals suggest that the stock is not just risky but also overvalued at its current price of 101.65.
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