Is Ionis Pharmaceuticals, Inc. technically bullish or bearish?

As of 7 July 2025, the technical trend for Ionis Pharmaceuticals, Inc. has changed from mildly bearish to bullish. The weekly and monthly MACD indicators are both bullish, supporting the positive trend. However, the RSI readings are bearish on both weekly and monthly time frames, indicating potential overbought conditions. The Bollinger Bands suggest a mildly bullish stance on the weekly and bullish on the monthly. Daily moving averages are bullish, while the KST is bullish weekly and mildly bullish monthly. Dow Theory shows no trend weekly but is mildly bullish monthly, and the OBV is bullish monthly.
In terms of performance, Ionis Pharmaceuticals has significantly outperformed the S&P 500 over the past month (42.16% vs. 2.33%) and year-to-date (76.60% vs. 12.22%), but it has lagged behind the benchmark over the longer three, five, and ten-year periods. Overall, the current technical stance is bullish, but caution is warranted due to the bearish RSI readings.