Is Lyra Therapeutics, Inc. overvalued or undervalued?

Jun 25 2025 09:04 AM IST
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As of August 9, 2022, Lyra Therapeutics, Inc. is considered overvalued and classified as risky, with concerning financial ratios including a price-to-book value of 8.31 and an ROE of -1111.31%, especially when compared to peers like ATAI Life Sciences and Eagle Pharmaceuticals.
As of 9 August 2022, the valuation grade for Lyra Therapeutics, Inc. moved from does not qualify to risky. The company is currently deemed overvalued. Key ratios indicate significant financial distress, with a price-to-book value of 8.31, an EV to EBITDA ratio of -0.10, and a staggering ROE of -1111.31%.

In comparison to peers, Lyra's valuation metrics are concerning; for instance, ATAI Life Sciences NV has a PE of -4.5969 and an EV to EBITDA of -3.9930, while Eagle Pharmaceuticals, Inc. is considered fairly valued with a PE of 2.1463 and an EV to EBITDA of 1.4923. Given these ratios and the overall market context, Lyra Therapeutics appears to be significantly overvalued relative to its peers and the broader industry.
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