Is ProQR Therapeutics NV overvalued or undervalued?

Sep 20 2025 06:29 PM IST
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As of November 4, 2021, ProQR Therapeutics NV is considered risky and overvalued, with key financial metrics indicating challenges in profitability, despite a strong 3-year return of 192% that has been overshadowed by a year-to-date decline of 17.36%.
As of 4 November 2021, the valuation grade for ProQR Therapeutics NV moved from does not qualify to risky. The company is currently overvalued based on its financial metrics. Key ratios include a Price to Book Value of 2.44, an EV to EBIT of -1.92, and an EV to Sales ratio of 3.42, which indicate significant challenges in profitability and valuation relative to its sales.

In comparison to its peers, ProQR Therapeutics NV has a P/E ratio of -5.81, while Esperion Therapeutics, Inc. has a P/E of -4.99, and Ocugen, Inc. stands at -5.65, all reflecting a risky valuation environment in the biotechnology sector. Despite a strong 3-year return of 192.0%, which outperformed the S&P 500's 70.41% return, the year-to-date performance of -17.36% suggests ongoing struggles that reinforce the notion of overvaluation.
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