Is Spyre Therapeutics, Inc. technically bullish or bearish?

As of 24 October 2025, the technical trend for Spyre Therapeutics, Inc. has changed from mildly bullish to bullish. The weekly MACD is bullish, supported by a bullish reading in the daily moving averages and a bullish KST on the weekly timeframe. However, the monthly MACD and KST are only mildly bullish, and the Bollinger Bands show a mildly bearish stance on the monthly chart. The Dow Theory indicates a mildly bullish trend on both weekly and monthly periods.
In terms of performance, Spyre Therapeutics has outperformed the S&P 500 over the past week and month, returning 4.01% and 37.47% respectively, while the S&P 500 returned 1.92% and 2.32%. However, the year-to-date return of 0.39% lags behind the S&P 500's 15.47%, and the one-year return is significantly negative at -30.65% compared to the S&P 500's 16.90%. Overall, the current technical stance is bullish, with moderate strength indicated by the mixed signals across different timeframes.