Krystal Biotech Experiences Revision in Its Stock Evaluation Amid Strong Market Performance

Oct 20 2025 05:28 PM IST
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Krystal Biotech, Inc. has recently adjusted its valuation, showcasing a P/E ratio of 27 and a price-to-book value of 4.02. The company demonstrates strong financial metrics, including a ROCE of 36.18% and a year-to-date stock return of 21.43%, outperforming the S&P 500.
Krystal Biotech, Inc., a small-cap player in the Pharmaceuticals and Biotechnology sector, has recently undergone a valuation adjustment. The company currently exhibits a P/E ratio of 27, alongside a price-to-book value of 4.02. Its EV to EBIT stands at 25.02, while the EV to EBITDA is recorded at 23.83. Notably, Krystal Biotech showcases a robust return on capital employed (ROCE) of 36.18% and a return on equity (ROE) of 14.98%.

In comparison to its peers, Krystal Biotech's valuation metrics indicate a distinct positioning within the industry. For instance, BridgeBio Pharma, Inc. is categorized as risky, while Elanco Animal Health, Inc. is noted as expensive. Halozyme Therapeutics, Inc. holds a fair valuation, and Bio-Techne Corp. is also classified as very expensive.

The company's stock performance has been noteworthy, with a year-to-date return of 21.43%, significantly outpacing the S&P 500's return of 13.30% during the same period. This performance trend highlights Krystal Biotech's competitive stance in the market, particularly over longer time frames, where it has achieved a remarkable 268.52% return over the past five years.
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