Orchestra Biomed Holdings Hits New 52-Week Low at $2.20

Sep 25 2025 04:53 PM IST
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Orchestra Biomed Holdings, Inc. has reached a new 52-week low, reflecting a challenging year marked by a significant decline in stock price. The company operates at a loss, with concerning financial metrics, including negative return on equity and operating cash flow, while consistently underperforming against the S&P 500.
Orchestra Biomed Holdings, Inc., a microcap player in the Pharmaceuticals & Biotechnology sector, has reached a new 52-week low of USD 2.20 as of September 24, 2025. This significant decline marks a stark contrast to its 52-week high of USD 6.50, reflecting a challenging year for the company, which has seen its stock price plummet by 69.71% over the past year.

The company's market capitalization stands at USD 147 million, and it currently operates at a loss, with a negative price-to-earnings ratio. Financial metrics indicate a concerning trend, including a return on equity of -6,969.90% and a debt-to-equity ratio of -18.90. Additionally, the company has reported negative operating cash flow, with the lowest figure recorded at USD -59.39 million.

Orchestra Biomed's performance has consistently lagged behind the S&P 500, with a return of -51.14% over the last year. This underperformance highlights the challenges the company faces in a competitive market, as it continues to navigate a difficult financial landscape.
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