Adverum Biotechnologies, Inc.

  • Market Cap: Micro Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US00773U1088
USD
4.17
0.01 (0.24%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.38 M

Shareholding (Mar 2025)

FII

9.66%

Held by 30 FIIs

DII

38.89%

Held by 20 DIIs

Promoter

33.92%

How big is Adverum Biotechnologies, Inc.?

22-Jun-2025

As of Jun 18, Adverum Biotechnologies, Inc. has a market capitalization of 48.47 million, with net sales of 1.00 million and a net profit of -133.56 million over the last four quarters. The company reported shareholder's funds of 70.71 million and total assets of 179.84 million as of Dec 24.

Market Cap: As of Jun 18, Adverum Biotechnologies, Inc. has a market capitalization of 48.47 million, categorizing it as a Micro Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Adverum Biotechnologies, Inc. reported net sales of 1.00 million and a net profit of -133.56 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 70.71 million and total assets of 179.84 million.

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What does Adverum Biotechnologies, Inc. do?

22-Jun-2025

Adverum Biotechnologies, Inc. is a clinical-stage gene therapy company focused on treating serious ocular and rare diseases. It has a market cap of $48.47 million and reported a net profit loss of $47 million as of March 2025.

Overview:<BR>Adverum Biotechnologies, Inc. is a clinical-stage gene therapy company targeting unmet medical needs for serious ocular and rare diseases within the Pharmaceuticals & Biotechnology industry.<BR><BR>Financial Snapshot:<BR>Most recent Net Profit: -47 Million (Quarterly Results - Mar 2025)<BR>Market cap: USD 48.47 Million (Micro Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making)<BR>Industry P/E: NA<BR>Dividend Yield: 0.00%<BR>Debt Equity: -2.87<BR>Return on Equity: -505.49%<BR>Price to Book: 1.83<BR><BR>Contact Details:<BR>Address: 800 Saginaw Drive, REDWOOD CITY CA: 94063<BR>Tel: 1 650 2726269<BR>Fax: 1 650 3298151<BR>Website: https://adverum.com/

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Who are in the management team of Adverum Biotechnologies, Inc.?

22-Jun-2025

As of March 2022, the management team of Adverum Biotechnologies, Inc. includes Patrick Machado (Independent Chairman), Dr. Laurent Fischer (CEO), and several independent directors: Dr. Mehdi Gasmi, Dr. Eric Carter, Ms. Rekha Hemrajani, Dr. Mark Lupher, and Mr. James Scopa. This team provides governance and strategic direction for the company.

As of March 2022, the management team of Adverum Biotechnologies, Inc. includes the following individuals:<BR><BR>- Mr. Patrick Machado, Independent Chairman of the Board<BR>- Dr. Laurent Fischer, Chief Executive Officer and Director<BR>- Dr. Mehdi Gasmi, Director<BR>- Dr. Eric Carter, Independent Director<BR>- Ms. Rekha Hemrajani, Independent Director<BR>- Dr. Mark Lupher, Independent Director<BR>- Mr. James Scopa, Independent Director<BR><BR>This team comprises a mix of executive leadership and independent directors, contributing to the governance and strategic direction of the company.

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Should I buy, sell or hold Adverum Biotechnologies, Inc.?

22-Jun-2025

Is Adverum Biotechnologies, Inc. overvalued or undervalued?

20-Sep-2025

As of November 4, 2024, Adverum Biotechnologies, Inc. is considered a risky investment due to its overvaluation indicated by a high Price to Book Value of 2.24, low EV to EBIT of 0.11, negative EV to Sales ratio of -16.73, and significant stock declines of -36.83% year-to-date and -97.62% over five years, contrasting sharply with the S&P 500's performance.

As of 4 November 2024, the valuation grade for Adverum Biotechnologies, Inc. has moved from does not qualify to risky, indicating a deterioration in its investment appeal. The company appears to be overvalued, given its high Price to Book Value of 2.24, an extremely low EV to EBIT of 0.11, and a negative EV to Sales ratio of -16.73. Compared to peers, Adverum's EV to EBITDA ratio of 0.11 is significantly lower than XOMA Corp.'s -22.9484 and Alimera Sciences, Inc.'s 27.2619, highlighting its relative underperformance.<BR><BR>In terms of stock performance, Adverum has faced substantial declines, with a year-to-date return of -36.83%, compared to a positive 12.22% for the S&P 500, and a staggering -97.62% over the past five years against a 96.61% gain for the index. This stark contrast reinforces the notion that Adverum is currently overvalued in the market.

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Is Adverum Biotechnologies, Inc. technically bullish or bearish?

20-Sep-2025

As of September 5, 2025, Adverum Biotechnologies, Inc. is in a mildly bearish trend, with daily moving averages and weekly indicators supporting this outlook, despite some mildly bullish signals from the MACD; the stock has significantly underperformed the S&P 500, with a year-to-date return of -36.83% compared to the index's 12.22%.

As of 5 September 2025, the technical trend for Adverum Biotechnologies, Inc. has changed from sideways to mildly bearish. The current stance is bearish, driven by daily moving averages indicating a mildly bearish position, while weekly indicators such as the Dow Theory and OBV also reflect a mildly bearish outlook. Although the MACD shows mildly bullish signals on both weekly and monthly time frames, the overall sentiment is tempered by the bearish monthly Bollinger Bands and KST. <BR><BR>In terms of performance, the stock has underperformed significantly compared to the S&P 500 across multiple periods, with a year-to-date return of -36.83% versus the S&P 500's 12.22%, and a one-year return of -57.80% compared to 17.14% for the index.

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Unrated Stock - No Analysis Available
stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 74 Million (Micro Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

1.83

stock-summary
Return on Equity

812.48%

stock-summary
Price to Book

-3.67

Revenue and Profits:
Net Sales:
(Quarterly Results - Jun 2025)
Net Profit:
-49 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
28.31%
0%
28.31%
6 Months
66.14%
0%
66.14%
1 Year
-34.12%
0%
-34.12%
2 Years
-49.61%
0%
-49.61%
3 Years
531.82%
0%
531.82%
4 Years
-76.31%
0%
-76.31%
5 Years
-97.08%
0%
-97.08%

Adverum Biotechnologies, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
11.84%
EBIT Growth (5y)
-41.51%
EBIT to Interest (avg)
-137.88
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-2.87
Sales to Capital Employed (avg)
0.01
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
2.24
EV to EBIT
0.11
EV to EBITDA
0.11
EV to Capital Employed
0.34
EV to Sales
-16.73
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
310.81%
ROE (Latest)
-505.49%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bullish
Bearish
Moving Averages
Mildly Bullish (Daily)
KST
Bullish
Bearish
Dow Theory
Mildly Bearish
No Trend
OBV
Bearish
Bearish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Strategic Entities

Domestic Funds

Held in 17 Schemes (17.54%)

Foreign Institutions

Held by 30 Foreign Institutions (9.66%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
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      }
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        "Mar'25",
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          "field": "Operating Profit (PBDIT) excl Other Income",
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          "val2": "-47.50",
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        {
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          "chgp": "",
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          "chgp": "",
          "chgp_class": "neutral"
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        {
          "field": "Consolidate Net Profit",
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          "val2": "-47.00",
          "chgp": "-4.68%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
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        "Dec'24",
        "Dec'23",
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          "field": "Consolidate Net Profit",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
0.00
0.00
Operating Profit (PBDIT) excl Other Income
-49.30
-47.50
-3.79%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-49.20
-47.00
-4.68%
Operating Profit Margin (Excl OI)
0.00%
0.00%
NA
USD in Million.
Net Sales

QoQ Growth in quarter ended Jun 2025 is 0.00% vs 0.00% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -4.68% vs -14.91% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
1.00
3.60
-72.22%
Operating Profit (PBDIT) excl Other Income
-149.50
-123.40
-21.15%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-130.90
-122.10
-7.21%
Operating Profit Margin (Excl OI)
-153,159.00%
-35,845.00%
-11,731.40%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is -72.22% vs 0.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is -7.21% vs 20.97% in Dec 2023

stock-summaryCompany CV
About Adverum Biotechnologies, Inc. stock-summary
stock-summary
Adverum Biotechnologies, Inc.
Pharmaceuticals & Biotechnology
Adverum Biotechnologies, Inc. is a clinical-stage gene therapy company targeting unmet medical needs for serious ocular and rare diseases. The Company is evaluating its gene therapy candidate, ADVM-022, as a one-time, intravitreal injection for the treatment of its lead indication, wet age-related macular degeneration. It has collaboration agreement with Regeneron Pharmaceuticals, Inc. to research, develop, and commercialize gene therapy products (AVA-311) for ophthalmic diseases. The Company develops gene therapy product candidates designed to provide durable efficacy by inducing sustained expression of a therapeutic protein. Its capabilities include clinical development, vector discovery, and in-house manufacturing, specifically in process development, assay development and current Good Manufacturing Practices (cGMP) quality control.
Company Coordinates stock-summary
Company Details
800 Saginaw Drive , REDWOOD CITY CA : 94063
stock-summary
Tel: 1 650 2726269
stock-summary
Registrar Details