ProQR Therapeutics NV

  • Market Cap: Micro Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: NL0010872495
USD
2.12
0.17 (8.72%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.27 M

Shareholding (Mar 2025)

FII

9.50%

Held by 19 FIIs

DII

85.99%

Held by 8 DIIs

Promoter

1.50%

How big is ProQR Therapeutics NV?

22-Jun-2025

As of Jun 18, ProQR Therapeutics NV has a market capitalization of 205.86 million, with net sales of 20.36 million and a net profit of -32.35 million over the latest four quarters. The company reported shareholder's funds of 91.70 million and total assets of 173.92 million as of Dec 24.

Market Cap: As of Jun 18, ProQR Therapeutics NV has a market capitalization of 205.86 million, classified as a Micro Cap.<BR><BR>Recent Quarterly Performance: For the latest four quarters, ProQR Therapeutics NV reported net sales of 20.36 million and a net profit of -32.35 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 91.70 million and total assets of 173.92 million.

Read More

What does ProQR Therapeutics NV do?

22-Jun-2025

ProQR Therapeutics N.V. is a pre-clinical biopharmaceutical company focused on developing RNA-based therapies for severe genetic disorders. As of March 2025, it has a market cap of $205.86 million, with net sales of $5 million and a net loss of $11 million.

Overview: <BR>ProQR Therapeutics N.V. is a pre-clinical stage biopharmaceutical company engaged in the discovery and development of RNA-based therapeutics for severe genetic disorders, operating within the Pharmaceuticals & Biotechnology industry and classified as a micro-cap company.<BR><BR>Financial Snapshot: <BR>Most recent Net Sales: 5 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -11 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 205.86 Million (Micro Cap)<BR><BR>Key Metrics: <BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.62 <BR>Return on Equity: -38.80% <BR>Price to Book: 2.41<BR><BR>Contact Details: <BR>Address: Zernikedreef 9, LEIDEN None: 2333 CK <BR>Tel: 31 854 894932 <BR>Website: https://www.proqr.com/

Read More

Who are in the management team of ProQR Therapeutics NV?

22-Jun-2025

As of March 2022, the management team of ProQR Therapeutics NV includes Mr. Dinko Valerio (Chairman) and five independent members: Mr. Bart Filius, Ms. Theresa Heggie, Ms. Alison Lawton, M. Antoine Papiernik, and Dr. James Shannon, who oversee the company's strategic direction and governance.

As of March 2022, the management team of ProQR Therapeutics NV includes the following members of the Board of Directors:<BR><BR>- Mr. Dinko Valerio, Independent Chairman of the Supervisory Board<BR>- Mr. Bart Filius, Independent Member of the Supervisory Board<BR>- Ms. Theresa Heggie, Independent Member of the Supervisory Board<BR>- Ms. Alison Lawton, Independent Member of the Supervisory Board<BR>- M. Antoine Papiernik, Independent Member of the Supervisory Board<BR>- Dr. James Shannon, Independent Member of the Supervisory Board<BR><BR>This team is responsible for overseeing the company's strategic direction and governance.

Read More

Should I buy, sell or hold ProQR Therapeutics NV?

22-Jun-2025

Is ProQR Therapeutics NV overvalued or undervalued?

20-Sep-2025

As of November 4, 2021, ProQR Therapeutics NV is considered risky and overvalued, with key financial metrics indicating challenges in profitability, despite a strong 3-year return of 192% that has been overshadowed by a year-to-date decline of 17.36%.

As of 4 November 2021, the valuation grade for ProQR Therapeutics NV moved from does not qualify to risky. The company is currently overvalued based on its financial metrics. Key ratios include a Price to Book Value of 2.44, an EV to EBIT of -1.92, and an EV to Sales ratio of 3.42, which indicate significant challenges in profitability and valuation relative to its sales.<BR><BR>In comparison to its peers, ProQR Therapeutics NV has a P/E ratio of -5.81, while Esperion Therapeutics, Inc. has a P/E of -4.99, and Ocugen, Inc. stands at -5.65, all reflecting a risky valuation environment in the biotechnology sector. Despite a strong 3-year return of 192.0%, which outperformed the S&P 500's 70.41% return, the year-to-date performance of -17.36% suggests ongoing struggles that reinforce the notion of overvaluation.

Read More

Is ProQR Therapeutics NV technically bullish or bearish?

20-Sep-2025

As of September 11, 2025, ProQR Therapeutics NV shows a mildly bullish trend with mixed technical indicators, including a bullish weekly MACD and mildly bearish monthly KST, while year-to-date performance is -17.36%, underperforming the S&P 500, but it has outperformed the index over the past year with a 21.67% return.

As of 11 September 2025, the technical trend for ProQR Therapeutics NV has changed from bullish to mildly bullish. The weekly MACD is bullish, while the monthly MACD is mildly bullish, indicating some positive momentum. The Bollinger Bands also reflect a mildly bullish stance on both weekly and monthly time frames. However, the KST shows a bullish weekly signal but is mildly bearish monthly, and Dow Theory indicates a mildly bearish stance on both time frames. The daily moving averages are mildly bullish, suggesting short-term support.<BR><BR>In terms of performance, ProQR has a year-to-date return of -17.36%, underperforming the S&P 500's 12.22%, but it has outperformed the index over the past year with a return of 21.67% compared to the S&P 500's 17.14%. Overall, the current technical stance is mildly bullish, but with mixed signals from various indicators.

Read More
iScoreScore
Click here to find our call on this stock
Strong Sell
Sell
Hold
Buy
Strong Buy

MarketsMojo — Loved in India, Now Global

The power of Mojo is now in 29 countries. Explore global equities with the same cutting-edge features you love.

Dashboard
1

  • OPERATING CASH FLOW(Y) Lowest at USD -46.66 MM
  • ROCE(HY) Lowest at -75.99%
  • NET SALES(Q) At USD 4.33 MM has Fallen at -14.94%
2

Risky - Negative EBITDA

3

Below par performance in long term as well as near term

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 254 Million (Micro Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-1.72

stock-summary
Return on Equity

-55.54%

stock-summary
Price to Book

3.23

Revenue and Profits:
Net Sales:
4 Million
(Quarterly Results - Jun 2025)
Net Profit:
-14 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-12.76%
0%
-12.76%
6 Months
19.1%
0%
19.1%
1 Year
-42.23%
0%
-42.23%
2 Years
22.54%
0%
22.54%
3 Years
57.04%
0%
57.04%
4 Years
-67.88%
0%
-67.88%
5 Years
-44.65%
0%
-44.65%

ProQR Therapeutics NV for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
80.01%
EBIT Growth (5y)
5.53%
EBIT to Interest (avg)
-28.73
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.62
Sales to Capital Employed (avg)
0.22
Tax Ratio
0.66%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
46.10%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
2.44
EV to EBIT
-1.92
EV to EBITDA
-2.09
EV to Capital Employed
-1.31
EV to Sales
3.42
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-38.80%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bearish
Bearish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Mildly Bearish
Dow Theory
Mildly Bearish
Mildly Bullish
OBV
Mildly Bullish
Mildly Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Foreign Institutions

Domestic Funds

Held in 7 Schemes (3.01%)

Foreign Institutions

Held by 19 Foreign Institutions (9.5%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -10.42% vs 4.35% in Mar 2025",
        "dir": -1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -30.19% vs -7.07% in Mar 2025",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "4.30",
          "val2": "4.80",
          "chgp": "-10.42%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-13.30",
          "val2": "-10.90",
          "chgp": "-22.02%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Exceptional Items",
          "val1": "-0.10",
          "val2": "0.30",
          "chgp": "-133.33%",
          "chgp_class": "negative"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-13.80",
          "val2": "-10.60",
          "chgp": "-30.19%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-3,250.50%",
          "val2": "-2,442.60%",
          "chgp": "-80.79%",
          "chgp_class": "negative"
        }
      ]
    }
  },
  {
    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'24",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in year ended Dec 2024 is 191.43% vs 84.21% in Dec 2023",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is 0.00% vs 55.56% in Dec 2023",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "20.40",
          "val2": "7.00",
          "chgp": "191.43%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-30.70",
          "val2": "-35.00",
          "chgp": "12.29%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "1.10",
          "val2": "1.30",
          "chgp": "-15.38%",
          "chgp_class": "positive"
        },
        {
          "field": "Exceptional Items",
          "val1": "0.40",
          "val2": "3.00",
          "chgp": "-86.67%",
          "chgp_class": "negative"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-30.00",
          "val2": "-30.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-1,645.70%",
          "val2": "-5,353.10%",
          "chgp": "370.74%",
          "chgp_class": "positive"
        }
      ]
    }
  }
]
Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
4.30
4.80
-10.42%
Operating Profit (PBDIT) excl Other Income
-13.30
-10.90
-22.02%
Interest
0.00
0.00
Exceptional Items
-0.10
0.30
-133.33%
Consolidate Net Profit
-13.80
-10.60
-30.19%
Operating Profit Margin (Excl OI)
-3,250.50%
-2,442.60%
-80.79%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is -10.42% vs 4.35% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -30.19% vs -7.07% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
20.40
7.00
191.43%
Operating Profit (PBDIT) excl Other Income
-30.70
-35.00
12.29%
Interest
1.10
1.30
-15.38%
Exceptional Items
0.40
3.00
-86.67%
Consolidate Net Profit
-30.00
-30.00
Operating Profit Margin (Excl OI)
-1,645.70%
-5,353.10%
370.74%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 191.43% vs 84.21% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 0.00% vs 55.56% in Dec 2023

stock-summaryCompany CV
About ProQR Therapeutics NV stock-summary
stock-summary
ProQR Therapeutics NV
Pharmaceuticals & Biotechnology
ProQR Therapeutics N.V. (ProQR), formerly ProQR Therapeutics B.V., is a pre-clinical stage biopharmaceutical company based in the Netherlands. The Company is engaged in the discovery and development of ribonucleic Acid (RNA)-based therapeutics for the treatment of severe genetic disorders. It designs its therapeutic candidates to specifically target and repair the defective messenger RNA, or Messenger Ribonucleic Acid (mRNA), that is transcribed from a mutated gene in order to restore the expression and function of normal, or wild-type protein. Its product candidates include QR-010, an RNA-based oligonucleotide for the treatment of cystic fibrosis (CF), QR-110, an oligonucleotide and for the treatment of Leber’s congenital amaurosis (LCA).
Company Coordinates stock-summary
Company Details
Zernikedreef 9 , LEIDEN None : 2333 CK
stock-summary
Tel: 31 854 894932
stock-summary
Registrar Details