Iovance Biotherapeutics, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US4622601007
USD
2.20
0.07 (3.04%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.6 M

Shareholding (Mar 2025)

FII

15.61%

Held by 149 FIIs

DII

45.2%

Held by 57 DIIs

Promoter

11.37%

How big is Iovance Biotherapeutics, Inc.?

22-Jun-2025

As of Jun 18, Iovance Biotherapeutics, Inc. has a market capitalization of 674.55 million, with net sales of 212.67 million and a net profit of -375.36 million over the latest four quarters. The company reported shareholder's funds of 710.40 million and total assets of 910.43 million as of Dec 24.

Market Cap: As of Jun 18, Iovance Biotherapeutics, Inc. has a market capitalization of 674.55 million, categorizing it as a Small Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Iovance Biotherapeutics, Inc. reported net sales of 212.67 million and a net profit of -375.36 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 710.40 million and total assets of 910.43 million.

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What does Iovance Biotherapeutics, Inc. do?

22-Jun-2025

Iovance Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing cell therapies for cancer immunotherapy. As of March 2025, it has a market cap of $674.55 million, with net sales of $49 million and a net loss of $116 million.

Overview:<BR>Iovance Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing cell therapies as novel cancer immunotherapy products, operating within the Pharmaceuticals & Biotechnology industry and categorized as a small-cap company.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 49 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -116 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 674.55 Million (Small Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -0.46 <BR>Return on Equity: -48.88% <BR>Price to Book: 0.88<BR><BR>Contact Details:<BR>Address: 999 Skyway Rd Ste 150, SAN CARLOS CA: 94070-2724 <BR>Tel: ['1 650 2607120', '1 212 8383777'] <BR>Fax: 1 302 7301370 <BR>Website: http://www.iovance.com/

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Should I buy, sell or hold Iovance Biotherapeutics, Inc.?

22-Jun-2025

Who are in the management team of Iovance Biotherapeutics, Inc.?

22-Jun-2025

As of March 2022, the management team of Iovance Biotherapeutics, Inc. includes Dr. Iain Dukes (Chairman), Dr. Maria Fardis (CEO), Dr. Athena Countouriotis, Mr. Ryan Maynard, Gen. (Retd.) Merrill McPeak, Mr. Wayne Rothbaum, and Dr. Michael Weiser as independent directors. They oversee the company's strategic direction and operations.

As of March 2022, the management team of Iovance Biotherapeutics, Inc. includes the following individuals:<BR><BR>- Dr. Iain Dukes, Chairman of the Board<BR>- Dr. Maria Fardis, President, Chief Executive Officer and Director<BR>- Dr. Athena Countouriotis, Director<BR>- Mr. Ryan Maynard, Independent Director<BR>- Gen. (Retd.) Merrill McPeak, Independent Director<BR>- Mr. Wayne Rothbaum, Independent Director<BR>- Dr. Michael Weiser, Independent Director<BR><BR>This team is responsible for guiding the strategic direction and operations of the company.

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Is Iovance Biotherapeutics, Inc. overvalued or undervalued?

20-Sep-2025

As of February 28, 2024, Iovance Biotherapeutics, Inc. is considered risky due to overvaluation indicated by a Price to Book Value of 0.89, an EV to Sales ratio of 1.57, a troubling ROCE of -95.61%, and a year-to-date stock performance of -70.27%, significantly underperforming the S&P 500's 12.22% return.

As of 28 February 2024, the valuation grade for Iovance Biotherapeutics, Inc. has moved from does not qualify to risky, indicating a significant deterioration in its valuation outlook. The company appears to be overvalued given its financial metrics, particularly with a Price to Book Value of 0.89 and an EV to Sales ratio of 1.57, which suggest that the market is pricing the stock higher than its book value and sales generation capabilities would justify. Additionally, the ROCE stands at a concerning -95.61%, reflecting severe inefficiencies in capital utilization.<BR><BR>In comparison to its peers, Iovance's valuation metrics are notably unfavorable; for instance, Rhythm Pharmaceuticals, Inc. has a PE ratio of -36.41, while Merus NV shows a PE of -13.18, both indicating greater losses than Iovance. The company's stock has underperformed significantly against the S&P 500, with a year-to-date return of -70.27% compared to the index's positive 12.22%, reinforcing the notion that the stock is not only overvalued but also struggling in the current market environment.

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Is Iovance Biotherapeutics, Inc. technically bullish or bearish?

07-Oct-2025

As of October 3, 2025, Iovance Biotherapeutics, Inc. shows a mildly bearish trend with mixed technical indicators, underperforming the S&P 500 significantly with a year-to-date return of -70.14%.

As of 3 October 2025, the technical trend for Iovance Biotherapeutics, Inc. has changed from bearish to mildly bearish. The current stance is mildly bearish, driven by a combination of indicators. The MACD shows a mildly bullish signal on the weekly timeframe but is bearish on the monthly. The RSI is bullish on the monthly but shows no signal on the weekly. Moving averages are bearish on the daily, while the KST indicates bullishness weekly but bearishness monthly. The Bollinger Bands are sideways weekly and mildly bearish monthly. <BR><BR>The stock has underperformed significantly compared to the S&P 500, with a year-to-date return of -70.14% versus the S&P's 14.18%, and a one-year return of -78.87% compared to the S&P's 17.82%.

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iScoreScore
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Strong Sell
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Strong Buy

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Dashboard
1

The company has declared Positive results for the last 4 consecutive quarters

  • OPERATING CASH FLOW(Y) Highest at USD -303.41 MM
  • NET PROFIT(HY) Higher at USD -227.82 MM
  • ROCE(HY) Highest at -53.16%
2

Risky - Negative EBITDA

3

Reducing Promoter Confidence

4

Below par performance in long term as well as near term

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 861 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.42

stock-summary
Return on Equity

-55.82%

stock-summary
Price to Book

1.23

Revenue and Profits:
Net Sales:
60 Million
(Quarterly Results - Jun 2025)
Net Profit:
-112 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-0.45%
0%
-0.45%
6 Months
20.88%
0%
20.88%
1 Year
-74.8%
0%
-74.8%
2 Years
-64.86%
0%
-64.86%
3 Years
-67.84%
0%
-67.84%
4 Years
-86.71%
0%
-86.71%
5 Years
-94.74%
0%
-94.74%

Iovance Biotherapeutics, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
199.88%
EBIT Growth (5y)
-18.25%
EBIT to Interest (avg)
-381.95
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.46
Sales to Capital Employed (avg)
0.11
Tax Ratio
0.86%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
94.26%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
0.89
EV to EBIT
-0.84
EV to EBITDA
-0.94
EV to Capital Employed
0.80
EV to Sales
1.57
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-95.61%
ROE (Latest)
-48.88%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bullish
Bearish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Mildly Bearish
Moving Averages
Mildly Bearish (Daily)
KST
Bearish
Bearish
Dow Theory
No Trend
Mildly Bearish
OBV
No Trend
Bearish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 73 Schemes (27.81%)

Foreign Institutions

Held by 149 Foreign Institutions (15.61%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - YoY",
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        "suffix": "YoY Growth in quarter ended Jun 2025 is 92.93% vs 15,450.00% in Jun 2024",
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        "prefix": "Consolidated Net Profit ",
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        "Jun'24",
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          "val2": "-91.10",
          "chgp": "-11.75%",
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          "chgp_class": "neutral"
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          "field": "Consolidate Net Profit",
          "val1": "-111.70",
          "val2": "-97.10",
          "chgp": "-15.04%",
          "chgp_class": "negative"
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          "field": "Operating Profit Margin (Excl OI)",
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          "val2": "-3,276.30%",
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        "Dec'24",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - YoYstock-summary
Jun'25
Jun'24
Change(%)
Net Sales
60.00
31.10
92.93%
Operating Profit (PBDIT) excl Other Income
-101.80
-91.10
-11.75%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-111.70
-97.10
-15.04%
Operating Profit Margin (Excl OI)
-1,897.80%
-3,276.30%
137.85%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in quarter ended Jun 2025 is 92.93% vs 15,450.00% in Jun 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in quarter ended Jun 2025 is -15.04% vs 8.83% in Jun 2024

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
164.10
1.20
13,575.00%
Operating Profit (PBDIT) excl Other Income
-351.70
-427.40
17.71%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-372.20
-444.00
16.17%
Operating Profit Margin (Excl OI)
-2,409.20%
-387,349.90%
38,494.07%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 13,575.00% vs 0.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 16.17% vs -12.15% in Dec 2023

stock-summaryCompany CV
About Iovance Biotherapeutics, Inc. stock-summary
stock-summary
Iovance Biotherapeutics, Inc.
Pharmaceuticals & Biotechnology
Iovance Biotherapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of cell therapies as novel cancer immunotherapy products designed to harness the power of a patient’s own immune system to eradicate cancer cells. The Company has developed a shorter manufacturing process for Tumor infiltrating lymphocyte (TIL) therapy known as Generation 2 (Gen 2), which yields a cryopreserved TIL product. Its lead product candidates include lifileucel for metastatic melanoma and LN-145 for metastatic cervical cancer. In addition to metastatic melanoma and metastatic cervical cancer, it is investigating TIL therapy and peripheral blood lymphocyte therapy for the treatment of squamous cell carcinoma of the head and neck, non-small cell lung cancer and chronic lymphocytic leukemia.
Company Coordinates stock-summary
Company Details
999 Skyway Rd Ste 150 , SAN CARLOS CA : 94070-2724
stock-summary
Tel: 1 650 26071201 212 8383777
stock-summary
Registrar Details