Ultragenyx Pharmaceutical, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US90400D1081
USD
36.54
3.07 (9.17%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.24 M

Shareholding (Mar 2025)

FII

17.41%

Held by 165 FIIs

DII

38.43%

Held by 53 DIIs

Promoter

1.61%

How big is Ultragenyx Pharmaceutical, Inc.?

22-Jun-2025

As of Jun 18, Ultragenyx Pharmaceutical, Inc. has a market capitalization of $3.47 billion, with net sales of $590.69 million and a net profit of -$549.58 million over the last four quarters. The company has shareholder's funds of $255.30 million and total assets of $1.50 billion as of Dec 24.

Market Cap: As of Jun 18, Ultragenyx Pharmaceutical, Inc. has a market capitalization of 3,465.91 million, categorizing it as a Small Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Ultragenyx reported net sales of 590.69 million and a net profit of -549.58 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company has shareholder's funds amounting to 255.30 million and total assets of 1,503.46 million.

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What does Ultragenyx Pharmaceutical, Inc. do?

22-Jun-2025

Ultragenyx Pharmaceutical, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for genetic diseases. As of March 2025, it reported net sales of $139 million and a net loss of $151 million, with a market cap of approximately $3.47 billion.

Overview:<BR>Ultragenyx Pharmaceutical, Inc. is a clinical-stage biopharmaceutical company focused on the identification, acquisition, development, and commercialization of products for the treatment of genetic diseases, operating within the Pharmaceuticals & Biotechnology industry and classified as a small-cap company.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 139 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -151 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 3,465.91 Million (Small Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: 2.49 <BR>Return on Equity: -377.52% <BR>Price to Book: 24.03<BR><BR>Contact Details:<BR>Address: 60 Leveroni Ct, NOVATO CA: 94949-5746 <BR>Tel: 1 415 4838800 <BR>Fax: 1 415 4838810 <BR>Website: https://www.ultragenyx.com/

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Should I buy, sell or hold Ultragenyx Pharmaceutical, Inc.?

22-Jun-2025

Who are in the management team of Ultragenyx Pharmaceutical, Inc.?

22-Jun-2025

As of March 2022, the management team of Ultragenyx Pharmaceutical, Inc. includes Mr. Daniel Welch as Independent Chairman and Dr. Emil Kakkis as President and CEO, along with several Independent Directors on the Board.

As of March 2022, the management team of Ultragenyx Pharmaceutical, Inc. includes the following individuals:<BR><BR>- Mr. Daniel Welch, who serves as the Independent Chairman of the Board.<BR>- Dr. Emil Kakkis, who is the President, Chief Executive Officer, and a Director.<BR><BR>Additionally, the Board of Directors includes several Independent Directors: Mr. William Aliski, Dr. Deborah Dunsire, Dr. Lars Ekman, Mr. Matthew Fust, and Mr. Michael Narachi.

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Is Ultragenyx Pharmaceutical, Inc. overvalued or undervalued?

20-Sep-2025

As of February 20, 2018, Ultragenyx Pharmaceutical, Inc. is considered risky and overvalued due to its high Price to Book Value of 24.36, negative EV to EBITDA of -8.10, and poor ROE of -377.52%, alongside significant underperformance against the S&P 500 with a YTD return of -30.81%.

As of 20 February 2018, the valuation grade for Ultragenyx Pharmaceutical, Inc. moved from does not qualify to risky, indicating increased concerns regarding its financial health. The company appears to be overvalued, given its high Price to Book Value of 24.36 and negative EV to EBITDA of -8.10, alongside a troubling ROE of -377.52%. In comparison to its peers, Madrigal Pharmaceuticals has a significantly worse P/E ratio of -35.88, while Corcept Therapeutics is categorized as very expensive with a P/E of 60.03, highlighting the relative valuation challenges Ultragenyx faces.<BR><BR>The company's stock has underperformed against the S&P 500 across multiple periods, with a staggering YTD return of -30.81% compared to the index's 12.22%. This trend of underperformance reinforces the notion that Ultragenyx is currently overvalued in the market.

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Is Ultragenyx Pharmaceutical, Inc. technically bullish or bearish?

30-Sep-2025

As of September 26, 2025, Ultragenyx Pharmaceutical, Inc. shows a mildly bearish trend with mixed indicators, underperforming the S&P 500 with a year-to-date return of -30.88% compared to 12.96%.

As of 26 September 2025, the technical trend for Ultragenyx Pharmaceutical, Inc. has changed from bearish to mildly bearish. The current stance is mildly bearish, driven by a combination of indicators. The weekly MACD is mildly bullish, while the monthly MACD remains bearish. The weekly RSI indicates bullish momentum, but the monthly RSI shows no signal. Moving averages on a daily basis are mildly bearish, and both the KST and Dow Theory indicate bearish trends on a monthly basis. <BR><BR>In terms of returns, the stock has underperformed compared to the S&P 500 across multiple periods, with a year-to-date return of -30.88% versus the S&P 500's 12.96%, and a one-year return of -47.34% compared to 15.64% for the index.

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iScoreScore
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Strong Sell
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Dashboard
1

Risky - Negative EBITDA

  • The stock is trading risky as compared to its average historical valuations
  • Over the past year, while the stock has generated a return of -28.85%, its profits have risen by 11.9%
2

Consistent Underperformance against the benchmark over the last 3 years

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 3,037 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

2.39

stock-summary
Return on Equity

-351.58%

stock-summary
Price to Book

20.07

Revenue and Profits:
Net Sales:
166 Million
(Quarterly Results - Jun 2025)
Net Profit:
-115 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
15.82%
0%
15.82%
6 Months
0.38%
0%
0.38%
1 Year
-21.71%
0%
-21.71%
2 Years
-9.01%
0%
-9.01%
3 Years
-9.04%
0%
-9.04%
4 Years
-51.93%
0%
-51.93%
5 Years
-70.57%
0%
-70.57%

Ultragenyx Pharmaceutical, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
30.79%
EBIT Growth (5y)
-6.22%
EBIT to Interest (avg)
-10.77
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
2.49
Sales to Capital Employed (avg)
0.44
Tax Ratio
0.45%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
24.36
EV to EBIT
-7.54
EV to EBITDA
-8.10
EV to Capital Employed
7.70
EV to Sales
6.56
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-102.05%
ROE (Latest)
-377.52%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bullish
Bearish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bullish
Bearish
Moving Averages
Mildly Bearish (Daily)
KST
Bullish
Bearish
Dow Theory
Mildly Bearish
Mildly Bullish
OBV
Mildly Bullish
Mildly Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 81 Schemes (42.52%)

Foreign Institutions

Held by 165 Foreign Institutions (17.41%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
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        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 19.53% vs -15.52% in Mar 2025",
        "dir": 1
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      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 23.89% vs -13.27% in Mar 2025",
        "dir": 1
      }
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    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
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      "body": [
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          "field": "Net Sales",
          "val1": "166.50",
          "val2": "139.30",
          "chgp": "19.53%",
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        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-99.30",
          "val2": "-133.90",
          "chgp": "25.84%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "14.00",
          "val2": "14.30",
          "chgp": "-2.10%",
          "chgp_class": "positive"
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          "val2": "-0.20",
          "chgp": "100.00%",
          "chgp_class": "positive"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-115.00",
          "val2": "-151.10",
          "chgp": "23.89%",
          "chgp_class": "positive"
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        {
          "field": "Operating Profit Margin (Excl OI)",
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          "val2": "-1,026.20%",
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        "Dec'24",
        "Dec'23",
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          "val2": "434.20",
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          "field": "Interest",
          "val1": "63.00",
          "val2": "66.00",
          "chgp": "-4.55%",
          "chgp_class": "positive"
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          "field": "Exceptional Items",
          "val1": "-1.10",
          "val2": "0.40",
          "chgp": "-375.00%",
          "chgp_class": "negative"
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          "field": "Consolidate Net Profit",
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          "chgp": "6.17%",
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          "val2": "-1,310.80%",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
166.50
139.30
19.53%
Operating Profit (PBDIT) excl Other Income
-99.30
-133.90
25.84%
Interest
14.00
14.30
-2.10%
Exceptional Items
-0.00
-0.20
100.00%
Consolidate Net Profit
-115.00
-151.10
23.89%
Operating Profit Margin (Excl OI)
-648.00%
-1,026.20%
37.82%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 19.53% vs -15.52% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is 23.89% vs -13.27% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
560.20
434.20
29.02%
Operating Profit (PBDIT) excl Other Income
-500.40
-543.20
7.88%
Interest
63.00
66.00
-4.55%
Exceptional Items
-1.10
0.40
-375.00%
Consolidate Net Profit
-569.20
-606.60
6.17%
Operating Profit Margin (Excl OI)
-956.70%
-1,310.80%
35.41%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 29.02% vs 19.52% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 6.17% vs 14.25% in Dec 2023

stock-summaryCompany CV
About Ultragenyx Pharmaceutical, Inc. stock-summary
stock-summary
Ultragenyx Pharmaceutical, Inc.
Pharmaceuticals & Biotechnology
Ultragenyx Pharmaceutical Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the identification, acquisition, development, and commercialization of products for the treatment of genetic diseases. Its clinical-stage pipeline consists of two product categories: biologics (including a monoclonal antibody and an enzyme replacement therapy), and small-molecule substrate replacement therapies. Its product candidates under biologics category include KRN23 (UX023) and recombinant human beta-glucuronidase (rhGUS) (UX003). Its product candidates under small-molecule category include UX007 and aceneuramic acid extended-release (Ace-ER) (UX001). It is also developing recombinant human protective protein cathepsin-A (rhPPCA). KRN23 is a fully human monoclonal antibody. rhGUS is an intravenous (IV) enzyme replacement therapy. UX007 is a substrate replacement therapy. It is developing Ace-ER for the treatment of GNE myopathy. rhPPCA is in preclinical development.
Company Coordinates stock-summary
Company Details
60 Leveroni Ct , NOVATO CA : 94949-5746
stock-summary
Tel: 1 415 4838800
stock-summary
Registrar Details