Taysha Gene Therapies, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US8776191061
USD
5.06
1 (24.63%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

5.62 M

Shareholding (Mar 2025)

FII

8.49%

Held by 55 FIIs

DII

62.76%

Held by 41 DIIs

Promoter

8.96%

How big is Taysha Gene Therapies, Inc.?

22-Jun-2025

As of Jun 18, Taysha Gene Therapies, Inc. has a market capitalization of 666.90 million and reported net sales of 7.22 million, with a net loss of 86.77 million over the latest four quarters.

As of Jun 18, Taysha Gene Therapies, Inc. has a market capitalization of 666.90 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the company reported net sales of 7.22 million for the latest four quarters, while the net profit for the same period was a loss of 86.77 million.<BR><BR>As of Dec 24, the reporting period shows shareholder's funds of 71.53 million and total assets amounting to 276.41 million.

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What does Taysha Gene Therapies, Inc. do?

22-Jun-2025

Taysha Gene Therapies, Inc. develops adeno-associated virus-based gene therapies for monogenic diseases of the central nervous system. As of March 2025, it has a market cap of $666.90 million, with net sales of $2 million and a net loss of $22 million.

Overview:<BR>Taysha Gene Therapies, Inc. is a gene therapy company focused on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system, operating in the Pharmaceuticals & Biotechnology industry with a micro-cap market capitalization.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 2 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -22 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 666.90 Million (Micro Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.31 <BR>Return on Equity: -149.22% <BR>Price to Book: 12.11<BR><BR>Contact Details:<BR>Address: 2280 Inwood Road, DALLAS TX: 75235 <BR>Tel: 1 214 6120000 <BR>Website: https://tayshagtx.com/

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Should I buy, sell or hold Taysha Gene Therapies, Inc.?

22-Jun-2025

Is Taysha Gene Therapies, Inc. overvalued or undervalued?

25-Jun-2025

As of March 28, 2023, Taysha Gene Therapies, Inc. is rated as "risky" and overvalued, with a Price to Book Value of 13.49, an EV to EBITDA of -8.12, a negative ROE of -149.22%, and a 1-year stock return of -15.88%, significantly underperforming the S&P 500's 10.26% return.

As of 28 March 2023, Taysha Gene Therapies, Inc. has moved from a grade of "does not qualify" to "risky." The company is currently considered overvalued. Key ratios include a Price to Book Value of 13.49, an EV to EBITDA of -8.12, and a negative ROE of -149.22%. <BR><BR>In comparison to its peers, Taysha's EV to EBITDA ratio is significantly worse than Poseida Therapeutics, Inc. at -13.33 and Verastem, Inc. at -1.91, both of which are also categorized as risky. The company's recent stock performance has been underwhelming, with a 1-year return of -15.88%, contrasting sharply with the S&P 500's 10.26% return in the same period, further indicating a challenging valuation landscape.

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Is Taysha Gene Therapies, Inc. technically bullish or bearish?

07-Oct-2025

As of October 3, 2025, Taysha Gene Therapies, Inc. shows a bullish technical trend with strong momentum indicators, despite a 78.31% decline over the past five years, while outperforming the S&P 500 year-to-date with a return of 155.49%.

As of 3 October 2025, the technical trend for Taysha Gene Therapies, Inc. has changed from mildly bullish to bullish. The weekly MACD is bullish, and the daily moving averages also indicate a bullish stance. Additionally, the Bollinger Bands show a bullish signal on the monthly timeframe. The KST is bullish on both weekly and monthly periods, while the monthly Dow Theory is mildly bullish. <BR><BR>Despite the current bullish indicators, the stock has experienced a significant decline over the past five years, down 78.31%, contrasting sharply with the S&P 500's 100.56% gain during the same period. However, in the shorter term, Taysha has outperformed the S&P 500 with a year-to-date return of 155.49% compared to the S&P's 14.18%. Overall, the current technical stance is bullish with strong momentum indicators.

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Dashboard
1

The company has declared negative results for the last 4 consecutive quarters

  • OPERATING CASH FLOW(Y) Lowest at USD -82.11 MM
  • NET SALES(9M) At USD 6.31 MM has Grown at -22.36%
  • OPERATING PROFIT(Q) Lowest at USD -26.48 MM
2

Risky - Negative EBITDA

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 884 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-1.09

stock-summary
Return on Equity

-35.17%

stock-summary
Price to Book

3.55

Revenue and Profits:
Net Sales:
2 Million
(Quarterly Results - Jun 2025)
Net Profit:
-27 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
74.48%
0%
74.48%
6 Months
82.01%
0%
82.01%
1 Year
93.87%
0%
93.87%
2 Years
175.0%
0%
175.0%
3 Years
115.32%
0%
115.32%
4 Years
-59.36%
0%
-59.36%
5 Years
-75.06%
0%
-75.06%

Taysha Gene Therapies, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
73.68%
EBIT Growth (5y)
3.80%
EBIT to Interest (avg)
-63.95
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.31
Sales to Capital Employed (avg)
0.26
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
13.49
EV to EBIT
-8.01
EV to EBITDA
-8.12
EV to Capital Employed
-38.70
EV to Sales
92.80
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-149.22%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Mildly Bullish
Moving Averages
Bullish (Daily)
KST
Bullish
Bullish
Dow Theory
Mildly Bearish
No Trend
OBV
Mildly Bearish
No Trend
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 31 Schemes (19.79%)

Foreign Institutions

Held by 55 Foreign Institutions (8.49%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
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        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -13.04% vs 15.00% in Mar 2025",
        "dir": -1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -25.12% vs -14.36% in Mar 2025",
        "dir": -1
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    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
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          "val2": "2.30",
          "chgp": "-13.04%",
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        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-26.50",
          "val2": "-21.10",
          "chgp": "-25.59%",
          "chgp_class": "negative"
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        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
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          "chgp": "-21.43%",
          "chgp_class": "negative"
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        {
          "field": "Consolidate Net Profit",
          "val1": "-26.90",
          "val2": "-21.50",
          "chgp": "-25.12%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
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          "val2": "-9,305.40%",
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          "chgp": "75.71%",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
2.00
2.30
-13.04%
Operating Profit (PBDIT) excl Other Income
-26.50
-21.10
-25.59%
Interest
0.00
0.00
Exceptional Items
-1.70
-1.40
-21.43%
Consolidate Net Profit
-26.90
-21.50
-25.12%
Operating Profit Margin (Excl OI)
-13,470.80%
-9,305.40%
-416.54%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is -13.04% vs 15.00% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -25.12% vs -14.36% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
8.30
15.50
-46.45%
Operating Profit (PBDIT) excl Other Income
-85.40
-70.00
-22.00%
Interest
0.10
5.00
-98.00%
Exceptional Items
-9.40
-38.70
75.71%
Consolidate Net Profit
-89.30
-111.60
19.98%
Operating Profit Margin (Excl OI)
-10,394.90%
-4,619.40%
-577.55%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is -46.45% vs 520.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 19.98% vs 32.77% in Dec 2023

stock-summaryCompany CV
About Taysha Gene Therapies, Inc. stock-summary
stock-summary
Taysha Gene Therapies, Inc.
Pharmaceuticals & Biotechnology
Taysha Gene Therapies, Inc. is a gene therapy company focused on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. Its product candidates include: TSHA-101, which is being developed for the treatment of GM2 gangliosidosis; TSHA-118, which is a AAV9 viral vector that expresses human codon-optimized Ceroid Lipofuscinosis Neuronal 1 complementary deoxyribonucleic acid under control of the chicken b-actin hybrid promoter; TSHA-102, which is being developed for the treatment of Rett syndrome; TSHA-103, which is being developed for the treatment of Solute Carrier Family 6 Member 1 (SLC6A1) haploinsufficiency disorder, and TSHA-104, which is being developed for the treatment for Surfeit locus 1.
Company Coordinates stock-summary
Company Details
2280 Inwood Road , DALLAS TX : 75235
stock-summary
Tel: 1 214 6120000
stock-summary
Registrar Details