Taysha Gene Therapies, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US8776191061
USD
4.54
0.14 (3.18%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.74 M

Shareholding (Dec 2025)

FII

12.51%

Held by 84 FIIs

DII

59.9%

Held by 49 DIIs

Promoter

9.24%

How big is Taysha Gene Therapies, Inc.?

22-Jun-2025

As of Jun 18, Taysha Gene Therapies, Inc. has a market capitalization of 666.90 million and reported net sales of 7.22 million, with a net loss of 86.77 million over the latest four quarters.

As of Jun 18, Taysha Gene Therapies, Inc. has a market capitalization of 666.90 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the company reported net sales of 7.22 million for the latest four quarters, while the net profit for the same period was a loss of 86.77 million.<BR><BR>As of Dec 24, the reporting period shows shareholder's funds of 71.53 million and total assets amounting to 276.41 million.

View full answer

What does Taysha Gene Therapies, Inc. do?

22-Jun-2025

Taysha Gene Therapies, Inc. develops adeno-associated virus-based gene therapies for monogenic diseases of the central nervous system. As of March 2025, it has a market cap of $666.90 million, with net sales of $2 million and a net loss of $22 million.

Overview:<BR>Taysha Gene Therapies, Inc. is a gene therapy company focused on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system, operating in the Pharmaceuticals & Biotechnology industry with a micro-cap market capitalization.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 2 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -22 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 666.90 Million (Micro Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.31 <BR>Return on Equity: -149.22% <BR>Price to Book: 12.11<BR><BR>Contact Details:<BR>Address: 2280 Inwood Road, DALLAS TX: 75235 <BR>Tel: 1 214 6120000 <BR>Website: https://tayshagtx.com/

View full answer

Should I buy, sell or hold Taysha Gene Therapies, Inc.?

22-Jun-2025

Is Taysha Gene Therapies, Inc. overvalued or undervalued?

25-Jun-2025

As of March 28, 2023, Taysha Gene Therapies, Inc. is rated as "risky" and overvalued, with a Price to Book Value of 13.49, an EV to EBITDA of -8.12, a negative ROE of -149.22%, and a 1-year stock return of -15.88%, significantly underperforming the S&P 500's 10.26% return.

As of 28 March 2023, Taysha Gene Therapies, Inc. has moved from a grade of "does not qualify" to "risky." The company is currently considered overvalued. Key ratios include a Price to Book Value of 13.49, an EV to EBITDA of -8.12, and a negative ROE of -149.22%. <BR><BR>In comparison to its peers, Taysha's EV to EBITDA ratio is significantly worse than Poseida Therapeutics, Inc. at -13.33 and Verastem, Inc. at -1.91, both of which are also categorized as risky. The company's recent stock performance has been underwhelming, with a 1-year return of -15.88%, contrasting sharply with the S&P 500's 10.26% return in the same period, further indicating a challenging valuation landscape.

View full answer

Is Taysha Gene Therapies, Inc. technically bullish or bearish?

07-Oct-2025

As of October 3, 2025, Taysha Gene Therapies, Inc. shows a bullish technical trend with strong momentum indicators, despite a 78.31% decline over the past five years, while outperforming the S&P 500 year-to-date with a return of 155.49%.

As of 3 October 2025, the technical trend for Taysha Gene Therapies, Inc. has changed from mildly bullish to bullish. The weekly MACD is bullish, and the daily moving averages also indicate a bullish stance. Additionally, the Bollinger Bands show a bullish signal on the monthly timeframe. The KST is bullish on both weekly and monthly periods, while the monthly Dow Theory is mildly bullish. <BR><BR>Despite the current bullish indicators, the stock has experienced a significant decline over the past five years, down 78.31%, contrasting sharply with the S&P 500's 100.56% gain during the same period. However, in the shorter term, Taysha has outperformed the S&P 500 with a year-to-date return of 155.49% compared to the S&P's 14.18%. Overall, the current technical stance is bullish with strong momentum indicators.

View full answer
iScoreScore
Click here to find our call on this stock
Strong Sell
Sell
Hold
Buy
Strong Buy

Dashboard

1

The company has declared negative results for the last 4 consecutive quarters

  • NET SALES(HY) At USD 1.99 MM has Grown at -31.52%
  • OPERATING CASH FLOW(Y) Lowest at USD -84.66 MM
  • RAW MATERIAL COST(Y) Grown by 101.22% (YoY)
2

Risky -

3

Reducing Promoter Confidence

stock-summaryMojo Parameters

Mojo Parameters

Stock DNA

stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 1,241 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-1.12

stock-summary
Return on Equity

-43.14%

stock-summary
Price to Book

5.67

Revenue and Profits:
Net Sales:
5 Million
(Quarterly Results - Dec 2025)
Net Profit:
-28 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-20.49%
0%
-20.49%
6 Months
55.48%
0%
55.48%
1 Year
176.83%
0%
176.83%
2 Years
39.69%
0%
39.69%
3 Years
548.66%
0%
548.66%
4 Years
-26.77%
0%
-26.77%
5 Years
-79.8%
0%
-79.8%

Taysha Gene Therapies, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions

News

Icon
No Recent News for the Company

Announcements stock-summary

Icon
No announcement available

Corporate Actions stock-summary

Icon
No corporate action available
stock-summaryKey Factors

Quality key factors stock-summary

Factor
Value
Sales Growth (5y)
64.43%
EBIT Growth (5y)
6.37%
EBIT to Interest (avg)
-63.95
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.31
Sales to Capital Employed (avg)
0.24
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0

Valuation key factors

Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
5.67
EV to EBIT
-9.75
EV to EBITDA
-9.86
EV to Capital Employed
-38.51
EV to Sales
157.85
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-43.14%

Technicals key factors

Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bearish
Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
No Trend
Mildly Bearish
OBV
No Trend
Mildly Bearish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Dec 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 36 Schemes (18.35%)

Foreign Institutions

Held by 84 Foreign Institutions (12.51%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Dec'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Dec 2025 is 0.00% vs -100.00% in Sep 2025",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Dec 2025 is 14.68% vs -21.56% in Sep 2025",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Dec'25",
        "Sep'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "5.50",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-28.00",
          "val2": "-33.70",
          "chgp": "16.91%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Exceptional Items",
          "val1": "-2.40",
          "val2": "-1.80",
          "chgp": "-33.33%",
          "chgp_class": "negative"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-27.90",
          "val2": "-32.70",
          "chgp": "14.68%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-5,159.50%",
          "val2": "0.00%",
          "chgp": "-515.95%",
          "chgp_class": "negative"
        }
      ]
    }
  },
  {
    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'25",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in year ended Dec 2025 is 18.07% vs -46.45% in Dec 2024",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2025 is -22.06% vs 19.98% in Dec 2024",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Dec'25",
        "Dec'24",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "9.80",
          "val2": "8.30",
          "chgp": "18.07%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-109.40",
          "val2": "-85.40",
          "chgp": "-28.10%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "0.10",
          "val2": "0.10",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Exceptional Items",
          "val1": "-7.40",
          "val2": "-9.40",
          "chgp": "21.28%",
          "chgp_class": "positive"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-109.00",
          "val2": "-89.30",
          "chgp": "-22.06%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-11,306.50%",
          "val2": "-10,394.90%",
          "chgp": "-91.16%",
          "chgp_class": "negative"
        }
      ]
    }
  }
]

Quarterly Results Snapshot (Consolidated) - Dec'25 - QoQstock-summary

Dec'25
Sep'25
Change(%)
Net Sales
5.50
0.00
Operating Profit (PBDIT) excl Other Income
-28.00
-33.70
16.91%
Interest
0.00
0.00
Exceptional Items
-2.40
-1.80
-33.33%
Consolidate Net Profit
-27.90
-32.70
14.68%
Operating Profit Margin (Excl OI)
-5,159.50%
0.00%
-515.95%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Dec 2025 is 0.00% vs -100.00% in Sep 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Dec 2025 is 14.68% vs -21.56% in Sep 2025

Annual Results Snapshot (Consolidated) - Dec'25stock-summary

Dec'25
Dec'24
Change(%)
Net Sales
9.80
8.30
18.07%
Operating Profit (PBDIT) excl Other Income
-109.40
-85.40
-28.10%
Interest
0.10
0.10
Exceptional Items
-7.40
-9.40
21.28%
Consolidate Net Profit
-109.00
-89.30
-22.06%
Operating Profit Margin (Excl OI)
-11,306.50%
-10,394.90%
-91.16%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2025 is 18.07% vs -46.45% in Dec 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2025 is -22.06% vs 19.98% in Dec 2024

stock-summaryCompany CV
About Taysha Gene Therapies, Inc. stock-summary
stock-summary
Taysha Gene Therapies, Inc.
Pharmaceuticals & Biotechnology
Taysha Gene Therapies, Inc. is a gene therapy company focused on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. Its product candidates include: TSHA-101, which is being developed for the treatment of GM2 gangliosidosis; TSHA-118, which is a AAV9 viral vector that expresses human codon-optimized Ceroid Lipofuscinosis Neuronal 1 complementary deoxyribonucleic acid under control of the chicken b-actin hybrid promoter; TSHA-102, which is being developed for the treatment of Rett syndrome; TSHA-103, which is being developed for the treatment of Solute Carrier Family 6 Member 1 (SLC6A1) haploinsufficiency disorder, and TSHA-104, which is being developed for the treatment for Surfeit locus 1.
Company Coordinates stock-summary
Company Details
2280 Inwood Road , DALLAS TX : 75235
stock-summary
Tel: 1 214 6120000
stock-summary
Registrar Details