Compare Madrigal Pharmaceuticals, Inc. with Similar Stocks
Stock DNA
Pharmaceuticals & Biotechnology
USD 10,113 Million (Small Cap)
NA (Loss Making)
NA
0.00%
-1.07
-47.37%
16.78
Revenue and Profits:
Net Sales:
321 Million
(Quarterly Results - Dec 2025)
Net Profit:
-59 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
6.65%
0%
6.65%
6 Months
21.56%
0%
21.56%
1 Year
60.16%
0%
60.16%
2 Years
150.37%
0%
150.37%
3 Years
67.51%
0%
67.51%
4 Years
577.85%
0%
577.85%
5 Years
295.97%
0%
295.97%
Madrigal Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
294.82%
EBIT Growth (5y)
-11.34%
EBIT to Interest (avg)
-116.13
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.03
Sales to Capital Employed (avg)
0.44
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
16.78
EV to EBIT
-31.54
EV to EBITDA
-31.70
EV to Capital Employed
-210.05
EV to Sales
9.88
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-47.37%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bullish
Mildly Bullish
Moving Averages
Bullish (Daily)
KST
Bearish
Bullish
Dow Theory
No Trend
No Trend
OBV
Mildly Bullish
No Trend
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 86 Schemes (33.27%)
Foreign Institutions
Held by 168 Foreign Institutions (11.52%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - YoY
Dec'25
Dec'24
Change(%)
Net Sales
321.10
103.30
210.84%
Operating Profit (PBDIT) excl Other Income
-59.20
-66.60
11.11%
Interest
8.30
3.50
137.14%
Exceptional Items
0.00
0.00
Consolidate Net Profit
-58.60
-59.40
1.35%
Operating Profit Margin (Excl OI)
-185.60%
-648.40%
46.28%
USD in Million.
Net Sales
YoY Growth in quarter ended Dec 2025 is 210.84% vs 0.00% in Dec 2024
Consolidated Net Profit
YoY Growth in quarter ended Dec 2025 is 1.35% vs 47.06% in Dec 2024
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
958.40
180.10
432.15%
Operating Profit (PBDIT) excl Other Income
-298.60
-496.80
39.90%
Interest
22.30
14.70
51.70%
Exceptional Items
-2.80
0.00
Consolidate Net Profit
-288.30
-465.90
38.12%
Operating Profit Margin (Excl OI)
-313.10%
-2,763.90%
245.08%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 432.15% vs 0.00% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 38.12% vs -24.71% in Dec 2024
About Madrigal Pharmaceuticals, Inc. 
Madrigal Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Madrigal Pharmaceuticals, Inc., formerly Synta Pharmaceuticals Corp., is a clinical-stage biopharmaceutical company. The Company focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular-metabolic diseases and nonalcoholic steatohepatitis (NASH). The Company's lead product, MGL-3196, is a Phase II-ready once-daily, oral, liver-directed selective thyroid hormone receptor-b (THR-b) agonist for the treatment of NASH, and heterozygous and homozygous familial hypercholesterolemia (FH). Its product pipeline also includes MGL-3745, which is used in the treatment of NASH and FH. MGL-3196 has completed Phase I single and multiple dose trials in healthy volunteers. MGL-3196 is being developed for dyslipidemia/hypercholesterolemia to lower low-density lipoproteins cholesterol, triglyceride levels and lipoprotein(a). MGL-3196 also reduces triglycerides in the plasma and liver by increasing fat metabolism and shows an anti-diabetic action.
Company Coordinates 
Company Details
200 Barr Harbor Dr Ste 400 , CONSHOHOCKEN PA : 19428-2978
Registrar Details






