Madrigal Pharmaceuticals, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US5588681057
USD
432.78
-0.42 (-0.1%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

254.46 k

Shareholding (Dec 2025)

FII

11.52%

Held by 168 FIIs

DII

51.43%

Held by 37 DIIs

Promoter

3.78%

How big is Madrigal Pharmaceuticals, Inc.?

22-Jun-2025

As of Jun 18, Madrigal Pharmaceuticals, Inc. has a market capitalization of $6.21 billion, with net sales of $317.38 million and a net profit of -$391.59 million over the latest four quarters. Shareholder's funds are $754.38 million, and total assets amount to $1.04 billion.

As of Jun 18, Madrigal Pharmaceuticals, Inc. has a market capitalization of 6,208.04 million, categorizing it as a Small Cap company.<BR><BR>As of Jun 18, the company reported net sales of 317.38 million for the latest four quarters. During the same period, it recorded a net profit of -391.59 million.<BR><BR>As of Dec 24, the reporting period shows shareholder's funds of 754.38 million and total assets amounting to 1,042.25 million.

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What does Madrigal Pharmaceuticals, Inc. do?

22-Jun-2025

Madrigal Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for cardiovascular-metabolic diseases and nonalcoholic steatohepatitis (NASH). As of March 2025, it reported net sales of $137 million and a net loss of $73 million, with a market cap of approximately $6.21 billion.

Overview: <BR>Madrigal Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing therapeutic candidates for cardiovascular-metabolic diseases and nonalcoholic steatohepatitis (NASH) within the Pharmaceuticals & Biotechnology industry.<BR><BR>Financial Snapshot: <BR>Net Sales: 137 Million (Quarterly Results - Mar 2025) <BR>Net Profit: -73 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 6,208.04 Million (Small Cap) <BR><BR>Key Metrics: <BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.03 <BR>Return on Equity: -55.10% <BR>Price to Book: 8.74 <BR><BR>Contact Details: <BR>Address: 200 Barr Harbor Dr Ste 400, CONSHOHOCKEN PA: 19428-2978 <BR>Tel: 1 404 3809263 <BR>Fax: 1 302 6555049 <BR>Website: http://www.madrigalpharma.com

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Should I buy, sell or hold Madrigal Pharmaceuticals, Inc.?

22-Jun-2025

Who are in the management team of Madrigal Pharmaceuticals, Inc.?

22-Jun-2025

As of March 2022, the management team of Madrigal Pharmaceuticals, Inc. includes Dr. Paul Friedman (CEO), Dr. Rebecca Taub (President of R&D and CMO), and several independent directors: Dr. Frederick Craves, Mr. Kenneth Bate, Mr. James Daly, Mr. Keith Gollust, and Dr. Richard Levy. They oversee the company's strategic direction and operations.

As of March 2022, the management team of Madrigal Pharmaceuticals, Inc. includes the following individuals:<BR><BR>- Dr. Paul Friedman: Chairman of the Board and Chief Executive Officer<BR>- Dr. Rebecca Taub: President of Research and Development, Chief Medical Officer, and Director<BR>- Dr. Frederick Craves: Lead Independent Director<BR>- Mr. Kenneth Bate: Independent Director<BR>- Mr. James Daly: Independent Director<BR>- Mr. Keith Gollust: Independent Director<BR>- Dr. Richard Levy: Independent Director<BR><BR>This team is responsible for overseeing the strategic direction and operations of the company.

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Is Madrigal Pharmaceuticals, Inc. overvalued or undervalued?

20-Sep-2025

As of August 7, 2024, Madrigal Pharmaceuticals, Inc. is considered risky and overvalued due to significant negative financial metrics, including a Price to Book Value of 8.69, an EV to Sales ratio of 17.17, and a troubling ROE of -55.10%, despite outperforming the S&P 500 with a 535.91% return over three years.

As of 7 August 2024, the valuation grade for Madrigal Pharmaceuticals, Inc. has moved from does not qualify to risky, indicating increased concerns regarding its financial health. The company appears to be overvalued given its significant negative metrics, including a Price to Book Value of 8.69 and an EV to Sales ratio of 17.17, which suggest that investors are paying a premium despite the lack of profitability. Additionally, the company's ROE stands at a troubling -55.10%, further underscoring its financial challenges.<BR><BR>In comparison to its peers, Madrigal's valuation ratios are starkly unfavorable; for instance, Corcept Therapeutics, Inc. has a P/E ratio of 60.03, while ACADIA Pharmaceuticals, Inc. presents a more attractive P/E of 19.28. The recent stock performance shows that Madrigal has outperformed the S&P 500 over multiple periods, with a remarkable 535.91% return over three years compared to the S&P 500's 70.41%. However, the overall financial metrics suggest that the stock is overvalued in light of its current operational struggles.

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Is Madrigal Pharmaceuticals, Inc. technically bullish or bearish?

28-Oct-2025

As of October 24, 2025, Madrigal Pharmaceuticals, Inc. shows a mildly bullish technical trend, supported by bullish weekly MACD and Bollinger Bands, despite mixed signals from other indicators, and has significantly outperformed the S&P 500 over the past year and three years.

As of 24 October 2025, the technical trend for Madrigal Pharmaceuticals, Inc. has changed from bullish to mildly bullish. The weekly MACD remains bullish, while the monthly MACD is also bullish. The Bollinger Bands indicate a mildly bullish stance on both weekly and monthly time frames. However, the KST shows a bullish weekly signal but a mildly bearish monthly signal, and Dow Theory presents a mildly bearish weekly view alongside a bullish monthly perspective. The daily moving averages are mildly bullish. <BR><BR>In terms of performance, Madrigal has outperformed the S&P 500 significantly over the past year with a return of 107.65% compared to the S&P 500's 16.90%, and over three years with a return of 504.39% against the S&P 500's 78.85%. Overall, the current technical stance is mildly bullish, supported by the weekly MACD and Bollinger Bands, despite mixed signals from other indicators.

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iScoreScore
Click here to find our call on this stock
Strong Sell
Sell
Hold
Buy
Strong Buy

Dashboard

1

Positive results in Dec 25

  • OPERATING CASH FLOW(Y) Highest at USD -189.55 MM
  • NET PROFIT(HY) Higher at USD -169.99 MM
  • INVENTORY TURNOVER RATIO(HY) Highest at 1.06 times
2

Risky -

3

Reducing Promoter Confidence

4

Market Beating Performance

stock-summaryMojo Parameters

Mojo Parameters

Stock DNA

stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 9,979 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-1.07

stock-summary
Return on Equity

-47.37%

stock-summary
Price to Book

16.56

Revenue and Profits:
Net Sales:
321 Million
(Quarterly Results - Dec 2025)
Net Profit:
-59 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-21.66%
0%
-21.66%
6 Months
0.62%
0%
0.62%
1 Year
31.48%
0%
31.48%
2 Years
69.5%
0%
69.5%
3 Years
79.1%
0%
79.1%
4 Years
335.96%
0%
335.96%
5 Years
273.47%
0%
273.47%

Madrigal Pharmaceuticals, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions

News

Icon
No Recent News for the Company

Announcements stock-summary

Icon
No announcement available

Corporate Actions stock-summary

Icon
No corporate action available
stock-summaryKey Factors

Quality key factors stock-summary

Factor
Value
Sales Growth (5y)
294.82%
EBIT Growth (5y)
-11.34%
EBIT to Interest (avg)
-116.13
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.03
Sales to Capital Employed (avg)
0.44
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0

Valuation key factors

Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
14.09
EV to EBIT
-29.45
EV to EBITDA
-29.58
EV to Capital Employed
681.96
EV to Sales
17.70
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-2315.67%
ROE (Latest)
-40.50%

Technicals key factors

Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
Bullish
No Signal
Bollinger Bands
Mildly Bearish
Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
No Trend
Mildly Bearish
OBV
No Trend
No Trend
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Dec 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 86 Schemes (33.27%)

Foreign Institutions

Held by 168 Foreign Institutions (11.52%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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          "field": "Consolidate Net Profit",
          "val1": "-58.60",
          "val2": "-59.40",
          "chgp": "1.35%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
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Quarterly Results Snapshot (Consolidated) - Dec'25 - YoYstock-summary

Dec'25
Dec'24
Change(%)
Net Sales
321.10
103.30
210.84%
Operating Profit (PBDIT) excl Other Income
-59.20
-66.60
11.11%
Interest
8.30
3.50
137.14%
Exceptional Items
0.00
0.00
Consolidate Net Profit
-58.60
-59.40
1.35%
Operating Profit Margin (Excl OI)
-185.60%
-648.40%
46.28%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in quarter ended Dec 2025 is 210.84% vs 0.00% in Dec 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in quarter ended Dec 2025 is 1.35% vs 47.06% in Dec 2024

Annual Results Snapshot (Consolidated) - Dec'25stock-summary

Dec'25
Dec'24
Change(%)
Net Sales
958.40
180.10
432.15%
Operating Profit (PBDIT) excl Other Income
-298.60
-496.80
39.90%
Interest
22.30
14.70
51.70%
Exceptional Items
-2.80
0.00
Consolidate Net Profit
-288.30
-465.90
38.12%
Operating Profit Margin (Excl OI)
-313.10%
-2,763.90%
245.08%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2025 is 432.15% vs 0.00% in Dec 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2025 is 38.12% vs -24.71% in Dec 2024

stock-summaryCompany CV
About Madrigal Pharmaceuticals, Inc. stock-summary
stock-summary
Madrigal Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Madrigal Pharmaceuticals, Inc., formerly Synta Pharmaceuticals Corp., is a clinical-stage biopharmaceutical company. The Company focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular-metabolic diseases and nonalcoholic steatohepatitis (NASH). The Company's lead product, MGL-3196, is a Phase II-ready once-daily, oral, liver-directed selective thyroid hormone receptor-b (THR-b) agonist for the treatment of NASH, and heterozygous and homozygous familial hypercholesterolemia (FH). Its product pipeline also includes MGL-3745, which is used in the treatment of NASH and FH. MGL-3196 has completed Phase I single and multiple dose trials in healthy volunteers. MGL-3196 is being developed for dyslipidemia/hypercholesterolemia to lower low-density lipoproteins cholesterol, triglyceride levels and lipoprotein(a). MGL-3196 also reduces triglycerides in the plasma and liver by increasing fat metabolism and shows an anti-diabetic action.
Company Coordinates stock-summary
Company Details
200 Barr Harbor Dr Ste 400 , CONSHOHOCKEN PA : 19428-2978
Registrar Details