Compare Rhythm Pharmaceuticals, Inc. with Similar Stocks
Stock DNA
Pharmaceuticals & Biotechnology
USD 6,659 Million (Small Cap)
NA (Loss Making)
NA
0.00%
-1.07
-128.63%
44.75
Revenue and Profits:
Net Sales:
51 Million
(Quarterly Results - Sep 2025)
Net Profit:
-53 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-5.3%
0%
-5.3%
6 Months
-6.7%
0%
-6.7%
1 Year
71.84%
0%
71.84%
2 Years
113.35%
0%
113.35%
3 Years
278.73%
0%
278.73%
4 Years
1051.14%
0%
1051.14%
5 Years
262.49%
0%
262.49%
Rhythm Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
181.04%
EBIT Growth (5y)
-8.88%
EBIT to Interest (avg)
-74.40
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-3.20
Sales to Capital Employed (avg)
0.40
Tax Ratio
0.07%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
-626.89
EV to EBIT
-41.87
EV to EBITDA
-42.24
EV to Capital Employed
-157.59
EV to Sales
47.54
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
Negative BV
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
Bearish
Bollinger Bands
Bearish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Mildly Bearish
Dow Theory
Mildly Bearish
Mildly Bearish
OBV
No Trend
Mildly Bearish
Shareholding Snapshot : Sep 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 68 Schemes (41.47%)
Foreign Institutions
Held by 114 Foreign Institutions (15.17%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Sep'25 - YoY
Sep'25
Sep'24
Change(%)
Net Sales
51.30
33.30
54.05%
Operating Profit (PBDIT) excl Other Income
-52.30
-43.50
-20.23%
Interest
4.70
5.20
-9.62%
Exceptional Items
-0.40
-0.50
20.00%
Consolidate Net Profit
-52.90
-43.60
-21.33%
Operating Profit Margin (Excl OI)
-1,026.40%
-1,319.80%
29.34%
USD in Million.
Net Sales
YoY Growth in quarter ended Sep 2025 is 54.05% vs 48.00% in Sep 2024
Consolidated Net Profit
YoY Growth in quarter ended Sep 2025 is -21.33% vs 1.36% in Sep 2024
Annual Results Snapshot (Consolidated) - Dec'24
Dec'24
Dec'23
Change(%)
Net Sales
130.10
77.40
68.09%
Operating Profit (PBDIT) excl Other Income
-263.90
-182.60
-44.52%
Interest
20.60
13.90
48.20%
Exceptional Items
7.50
0.20
3,650.00%
Consolidate Net Profit
-260.60
-184.70
-41.09%
Operating Profit Margin (Excl OI)
-2,040.40%
-2,381.00%
34.06%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2024 is 68.09% vs 227.97% in Dec 2023
Consolidated Net Profit
YoY Growth in year ended Dec 2024 is -41.09% vs -1.99% in Dec 2023
About Rhythm Pharmaceuticals, Inc. 
Rhythm Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of peptide therapeutics for the treatment of rare genetic deficiencies that result in life-threatening metabolic disorders. The Company’s lead peptide product candidate is setmelanotide, a potent, first-in-class melanocortin-4 receptor, or MC4R, agonist for the treatment of rare genetic disorders of obesity. Setmelanotide serves as replacement therapy for the treatment of melanocortin-4, or MC4, pathway deficiencies. MC4 pathway deficiencies result in the disruption of satiety signals and energy homeostasis in the body, which, in turn, leads to intense feelings of hunger and to obesity. The Company also focused on obesity related to six single gene-related, or monogenic, MC4 pathway deficiencies pro-opiomelanocortin, or POMC, leptin receptor, or LepR, Bardet-Biedl syndrome, Alstrom syndrome, POMC heterozygous, and POMC epigenetic disorders.
Company Coordinates 
Company Details
222 Berkeley St Fl 12 , BOSTON MA : 02116-3733
Registrar Details






