Rhythm Pharmaceuticals, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US76243J1051
USD
105.70
4.31 (4.25%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

575.89 k

Shareholding (Mar 2025)

FII

12.74%

Held by 108 FIIs

DII

41.52%

Held by 44 DIIs

Promoter

8.63%

How big is Rhythm Pharmaceuticals, Inc.?

22-Jun-2025

As of Jun 18, Rhythm Pharmaceuticals, Inc. has a market capitalization of $3.94 billion, with net sales of $136.86 million and a net profit of -$168.69 million over the last four quarters. Shareholder's funds are $21.73 million, and total assets amount to $393.47 million.

As of Jun 18, Rhythm Pharmaceuticals, Inc. has a market capitalization of 3,942.62 million, categorizing it as a Small Cap company.<BR><BR>As of Jun 18, the sum of Net Sales for the latest four quarters is 136.86 million, while the sum of Net Profit for the same period is -168.69 million.<BR><BR>As of Dec 24, the reporting period shows Shareholder's Funds at 21.73 million and Total Assets at 393.47 million.

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What does Rhythm Pharmaceuticals, Inc. do?

22-Jun-2025

Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company that develops peptide therapeutics for rare genetic metabolic disorders. As of March 2025, it reported net sales of $33 million and a net loss of $49 million, with a market cap of approximately $3.94 billion.

Overview: <BR>Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing peptide therapeutics for rare genetic deficiencies that lead to life-threatening metabolic disorders, operating within the Pharmaceuticals & Biotechnology industry and classified as a small-cap company.<BR><BR>Financial Snapshot: <BR>Most recent Net Sales: 33 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -49 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 3,942.62 Million (Small Cap)<BR><BR>Key Metrics: <BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -3.20 <BR>Return on Equity: -926.82% <BR>Price to Book: 208.09<BR><BR>Contact Details: <BR>Address: 222 Berkeley St Fl 12, BOSTON MA: 02116-3733 <BR>Tel: ['1 857 2644280', '1 212 3621200'] <BR>Fax: 1 857 2644299 <BR>Website: http://www.rhythmtx.com

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Should I buy, sell or hold Rhythm Pharmaceuticals, Inc.?

22-Jun-2025

Who are in the management team of Rhythm Pharmaceuticals, Inc.?

22-Jun-2025

As of March 2022, Rhythm Pharmaceuticals' management team is led by Dr. David Meeker as Chairman, President, and CEO, alongside a diverse Board of Directors that includes Dr. Camille Bedrosian, Mrs. Lynn Tetrault, Mr. Stuart Arbuckle, Mr. Todd Foley, and Ms. Jennifer Good.

As of March 2022, the management team of Rhythm Pharmaceuticals, Inc. includes Dr. David Meeker, who serves as the Chairman of the Board, President, and Chief Executive Officer. Other members of the Board of Directors are Dr. Camille Bedrosian, Mrs. Lynn Tetrault, Mr. Stuart Arbuckle, Mr. Todd Foley, and Ms. Jennifer Good, all of whom hold various director positions. <BR><BR>In summary, the key management personnel are Dr. David Meeker, along with a diverse board consisting of both independent and non-independent directors.

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Is Rhythm Pharmaceuticals, Inc. overvalued or undervalued?

20-Sep-2025

As of November 2, 2021, Rhythm Pharmaceuticals, Inc. is considered risky and overvalued due to significant negative financial metrics, including a Price to Book Value of 228.70 and a P/E ratio of -36.41, despite a strong year-to-date return of 76.03%.

As of 2 November 2021, the valuation grade for Rhythm Pharmaceuticals, Inc. moved from does not qualify to risky, indicating a heightened level of uncertainty regarding its financial stability. The company appears to be overvalued given its significant negative financial metrics, including a Price to Book Value of 228.70, an EV to EBIT of -24.75, and an EV to EBITDA of -24.97. These ratios suggest that the company is struggling to generate positive earnings relative to its valuation.<BR><BR>In comparison to its peers, Rhythm Pharmaceuticals, Inc. has a P/E ratio of -36.41, which is significantly worse than Merus NV at -13.18 and CymaBay Therapeutics, Inc. at -35.38, highlighting its relative overvaluation in the market. Despite its strong year-to-date return of 76.03% compared to the S&P 500's 12.22%, this performance does not mitigate the concerns raised by its negative financial ratios, reinforcing the conclusion that the company is overvalued.

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Is Rhythm Pharmaceuticals, Inc. technically bullish or bearish?

28-Oct-2025

As of October 24, 2025, Rhythm Pharmaceuticals, Inc. is in a bullish trend with strong momentum indicators, despite some bearish signals in RSI and KST, and has significantly outperformed the S&P 500 with a year-to-date return of 97.34%.

As of 24 October 2025, the technical trend for Rhythm Pharmaceuticals, Inc. has changed from mildly bullish to bullish. The weekly and monthly MACD indicators are bullish, while the Bollinger Bands also indicate bullishness across both time frames. The daily moving averages confirm a bullish stance. However, the weekly and monthly RSI readings are bearish, suggesting some weakness in momentum. The KST is mildly bearish on both weekly and monthly charts, and Dow Theory shows no trend weekly but is bullish monthly. Overall, the stock is currently bullish, driven by strong momentum indicators despite some bearish signals in RSI and KST.<BR><BR>In terms of performance, the stock has significantly outperformed the S&P 500 across all periods, with a year-to-date return of 97.34% compared to the S&P 500's 15.47%, and a one-year return of 122.23% versus 16.90%.

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iScoreScore
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Strong Sell
Sell
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Strong Buy

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1

With a Operating Losses, the company has a Weak Long Term Fundamental Strength

  • Poor long term growth as Operating profit has grown by an annual rate -6.38% of over the last 5 years
  • Company's ability to service its debt is weak with a poor EBIT to Interest (avg) ratio of -74.40
2

Positive results in Jun 25

3

Risky - Negative EBITDA

4

Reducing Promoter Confidence

5

Consistent Returns over the last 3 years

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 6,627 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

2.96

stock-summary
Return on Equity

1,528.51%

stock-summary
Price to Book

-556.49

Revenue and Profits:
Net Sales:
49 Million
(Quarterly Results - Jun 2025)
Net Profit:
-47 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
3.94%
0%
3.94%
6 Months
60.96%
0%
60.96%
1 Year
75.93%
0%
75.93%
2 Years
212.81%
0%
212.81%
3 Years
273.23%
0%
273.23%
4 Years
1097.06%
0%
1097.06%
5 Years
264.73%
0%
264.73%

Rhythm Pharmaceuticals, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
175.00%
EBIT Growth (5y)
-6.38%
EBIT to Interest (avg)
-74.40
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-3.20
Sales to Capital Employed (avg)
0.37
Tax Ratio
0.07%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
228.70
EV to EBIT
-24.75
EV to EBITDA
-24.97
EV to Capital Employed
-102.58
EV to Sales
31.22
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-926.82%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
Bearish
Bollinger Bands
Bullish
Mildly Bullish
Moving Averages
Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
Mildly Bullish
Bullish
OBV
Mildly Bearish
No Trend
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 68 Schemes (37.11%)

Foreign Institutions

Held by 108 Foreign Institutions (12.74%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - YoY",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in quarter ended Jun 2025 is 66.67% vs 51.56% in Jun 2024",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in quarter ended Jun 2025 is -44.27% vs 30.84% in Jun 2024",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Jun'24",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "48.50",
          "val2": "29.10",
          "chgp": "66.67%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-44.90",
          "val2": "-40.10",
          "chgp": "-11.97%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "5.80",
          "val2": "4.60",
          "chgp": "26.09%",
          "chgp_class": "negative"
        },
        {
          "field": "Exceptional Items",
          "val1": "-0.30",
          "val2": "7.60",
          "chgp": "-103.95%",
          "chgp_class": "negative"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-46.60",
          "val2": "-32.30",
          "chgp": "-44.27%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-933.90%",
          "val2": "-1,392.00%",
          "chgp": "45.81%",
          "chgp_class": "positive"
        }
      ]
    }
  },
  {
    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'24",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in year ended Dec 2024 is 68.09% vs 227.97% in Dec 2023",
        "dir": -1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is -41.09% vs -1.99% in Dec 2023",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "130.10",
          "val2": "77.40",
          "chgp": "68.09%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-263.90",
          "val2": "-182.60",
          "chgp": "-44.52%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "20.60",
          "val2": "13.90",
          "chgp": "48.20%",
          "chgp_class": "negative"
        },
        {
          "field": "Exceptional Items",
          "val1": "7.50",
          "val2": "0.20",
          "chgp": "3,650.00%",
          "chgp_class": "positive"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-260.60",
          "val2": "-184.70",
          "chgp": "-41.09%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-2,040.40%",
          "val2": "-2,381.00%",
          "chgp": "34.06%",
          "chgp_class": "positive"
        }
      ]
    }
  }
]
Quarterly Results Snapshot (Consolidated) - Jun'25 - YoYstock-summary
Jun'25
Jun'24
Change(%)
Net Sales
48.50
29.10
66.67%
Operating Profit (PBDIT) excl Other Income
-44.90
-40.10
-11.97%
Interest
5.80
4.60
26.09%
Exceptional Items
-0.30
7.60
-103.95%
Consolidate Net Profit
-46.60
-32.30
-44.27%
Operating Profit Margin (Excl OI)
-933.90%
-1,392.00%
45.81%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in quarter ended Jun 2025 is 66.67% vs 51.56% in Jun 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in quarter ended Jun 2025 is -44.27% vs 30.84% in Jun 2024

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
130.10
77.40
68.09%
Operating Profit (PBDIT) excl Other Income
-263.90
-182.60
-44.52%
Interest
20.60
13.90
48.20%
Exceptional Items
7.50
0.20
3,650.00%
Consolidate Net Profit
-260.60
-184.70
-41.09%
Operating Profit Margin (Excl OI)
-2,040.40%
-2,381.00%
34.06%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 68.09% vs 227.97% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is -41.09% vs -1.99% in Dec 2023

stock-summaryCompany CV
About Rhythm Pharmaceuticals, Inc. stock-summary
stock-summary
Rhythm Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Rhythm Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on the development and commercialization of peptide therapeutics for the treatment of rare genetic deficiencies that result in life-threatening metabolic disorders. The Company’s lead peptide product candidate is setmelanotide, a potent, first-in-class melanocortin-4 receptor, or MC4R, agonist for the treatment of rare genetic disorders of obesity. Setmelanotide serves as replacement therapy for the treatment of melanocortin-4, or MC4, pathway deficiencies. MC4 pathway deficiencies result in the disruption of satiety signals and energy homeostasis in the body, which, in turn, leads to intense feelings of hunger and to obesity. The Company also focused on obesity related to six single gene-related, or monogenic, MC4 pathway deficiencies pro-opiomelanocortin, or POMC, leptin receptor, or LepR, Bardet-Biedl syndrome, Alstrom syndrome, POMC heterozygous, and POMC epigenetic disorders.
Company Coordinates stock-summary
Company Details
222 Berkeley St Fl 12 , BOSTON MA : 02116-3733
stock-summary
Tel: 1 857 26442801 212 3621200
stock-summary
Registrar Details