Compare Krystal Biotech, Inc. with Similar Stocks
Dashboard
1
Poor Management Efficiency with a low ROE of 4.74%
- The company has been able to generate a Return on Equity (avg) of 4.74% signifying low profitability per unit of shareholders funds
2
The company has declared Positive results for the last 7 consecutive quarters
3
With ROE of 15.20%, it has a very expensive valuation with a 5.45 Price to Book Value
4
High Institutional Holdings at 100%
5
Company is among the highest 1% of companies rated by MarketsMojo across all 4,000 stocks
6
Consistent Returns over the last 3 years
Stock DNA
Pharmaceuticals & Biotechnology
USD 7,653 Million (Small Cap)
36.00
NA
0.00%
-0.68
16.80%
6.28
Revenue and Profits:
Net Sales:
107 Million
(Quarterly Results - Dec 2025)
Net Profit:
51 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
29.51%
0%
29.51%
6 Months
82.47%
0%
82.47%
1 Year
46.17%
0%
46.17%
2 Years
146.65%
0%
146.65%
3 Years
250.96%
0%
250.96%
4 Years
375.56%
0%
375.56%
5 Years
258.66%
0%
258.66%
Krystal Biotech, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
229.79%
EBIT Growth (5y)
47.08%
EBIT to Interest (avg)
-32.99
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.63
Sales to Capital Employed (avg)
0.23
Tax Ratio
10.19%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
7.24%
ROE (avg)
4.74%
Valuation key factors
Factor
Value
P/E Ratio
36
Industry P/E
Price to Book Value
5.45
EV to EBIT
32.88
EV to EBITDA
31.58
EV to Capital Employed
13.85
EV to Sales
13.90
PEG Ratio
1.79
Dividend Yield
NA
ROCE (Latest)
42.13%
ROE (Latest)
15.20%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Mildly Bullish
Moving Averages
Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
No Trend
Bullish
OBV
No Trend
Bullish
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 85 Schemes (55.03%)
Foreign Institutions
Held by 157 Foreign Institutions (10.85%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - YoY
Dec'25
Dec'24
Change(%)
Net Sales
107.10
91.10
17.56%
Operating Profit (PBDIT) excl Other Income
46.00
43.00
6.98%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
51.40
45.50
12.97%
Operating Profit Margin (Excl OI)
413.30%
454.00%
-4.07%
USD in Million.
Net Sales
YoY Growth in quarter ended Dec 2025 is 17.56% vs 116.39% in Dec 2024
Consolidated Net Profit
YoY Growth in quarter ended Dec 2025 is 12.97% vs 422.99% in Dec 2024
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
389.10
290.50
33.94%
Operating Profit (PBDIT) excl Other Income
167.80
109.90
52.68%
Interest
0.00
0.00
Exceptional Items
0.00
-37.50
100.00%
Consolidate Net Profit
204.80
89.20
129.60%
Operating Profit Margin (Excl OI)
414.50%
355.20%
5.93%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 33.94% vs 472.98% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 129.60% vs 718.35% in Dec 2024
About Krystal Biotech, Inc. 
Krystal Biotech, Inc.
Pharmaceuticals & Biotechnology
Krystal Biotech, Inc. is a gene therapy company. The Company is engaged in developing and commercializing novel treatments for patients suffering from dermatological diseases. The Company has developed a Skin TARgeted Delivery platform, or STAR-D platform, that consists of a patent pending engineered viral vector based on herpes simplex virus 1, or HSV-1, and skin-optimized gene transfer technology, to develop off-the-shelf treatments for dermatological diseases. The Company’s products include KB103 and KB104.The Company's KB103 is in preclinical development to treat dystrophic epidermolysis bullosa, or DEB, a rare and severe genetic disease. The Company's KB104 is to treat Netherton Syndrome, a severe form of ichthyosis, which is a family of genetic skin disorders associated with thickened scaly skin and characterized by chronic skin inflammation, itchiness and dehydration.
Company Coordinates 
Company Details
2100 Wharton St Ste 701 , PITTSBURGH PA : 15203-1973
Registrar Details






