Krystal Biotech, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US5011471027
USD
221.96
6.9 (3.21%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

406.34 k

Shareholding (Mar 2025)

FII

12.15%

Held by 139 FIIs

DII

28.07%

Held by 61 DIIs

Promoter

3.94%

How big is Krystal Biotech, Inc.?

22-Jun-2025

As of Jun 18, Krystal Biotech, Inc. has a market capitalization of $3.76 billion, with net sales of $333.44 million and a net profit of $123.96 million over the latest four quarters.

Market Cap: As of Jun 18, Krystal Biotech, Inc. has a market capitalization of 3,757.41 million, classifying it as a Small Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Krystal Biotech, Inc. reported net sales of 333.44 million and a net profit of 123.96 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 946.38 million and total assets of 1,055.84 million.

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What does Krystal Biotech, Inc. do?

22-Jun-2025

Krystal Biotech, Inc. is a gene therapy company focused on developing treatments for dermatological diseases, with a market cap of approximately $3.76 billion. As of March 2025, it reported net sales of $88 million and a net profit of $36 million.

Overview: <BR>Krystal Biotech, Inc. is a gene therapy company engaged in developing and commercializing novel treatments for patients suffering from dermatological diseases, operating within the Pharmaceuticals & Biotechnology industry and classified as a small-cap company.<BR><BR>Financial Snapshot: <BR>Most recent Net Sales: 88 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: 36 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 3,757.41 Million (Small Cap)<BR><BR>Key Metrics: <BR>P/E: 27.00 <BR>Dividend Yield: 0.00% <BR>Debt Equity: -0.63 <BR>Return on Equity: 14.98% <BR>Price to Book: 3.82<BR><BR>Contact Details: <BR>Address: 2100 Wharton St Ste 701, PITTSBURGH PA: 15203-1973 <BR>Tel: 1 412 5865830 <BR>Website: https://www.krystalbio.com/

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Should I buy, sell or hold Krystal Biotech, Inc.?

22-Jun-2025

Who are in the management team of Krystal Biotech, Inc.?

22-Jun-2025

As of March 2022, the management team of Krystal Biotech, Inc. includes Chairman and CEO Mr. Krish Krishnan, COO Mrs. Suma Krishnan, Lead Independent Director Mr. R. Douglas Norby, and Directors Dr. Jing Marantz, Dr. Christopher Mason, Mr. Julian Gangolli, and Mr. Kirti Ganorkar. They oversee the company's strategic direction and operations.

As of March 2022, the management team of Krystal Biotech, Inc. includes:<BR><BR>- Mr. Krish Krishnan, who serves as the Chairman of the Board, President, and Chief Executive Officer.<BR>- Mrs. Suma Krishnan, the Founder, Chief Operating Officer, and Director.<BR>- Mr. R. Douglas Norby, who is the Lead Independent Director.<BR>- Dr. Jing Marantz, serving as a Director.<BR>- Dr. Christopher Mason, also a Director.<BR>- Mr. Julian Gangolli, who is an Independent Director.<BR>- Mr. Kirti Ganorkar, another Independent Director. <BR><BR>This team is responsible for guiding the company's strategic direction and operations.

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Is Krystal Biotech, Inc. technically bullish or bearish?

30-Sep-2025

As of September 26, 2025, Krystal Biotech, Inc. shows a mildly bullish technical trend, with mixed signals across time frames, outperforming the S&P 500 in the short term but underperforming over the past year.

As of 26 September 2025, the technical trend for Krystal Biotech, Inc. has changed from sideways to mildly bullish. The weekly MACD is mildly bullish, while the monthly MACD is mildly bearish, indicating mixed signals across time frames. The RSI shows a bullish stance on the monthly chart but no signal on the weekly. Bollinger Bands are bullish weekly but sideways monthly, and the KST is bullish weekly while mildly bearish monthly. The Dow Theory indicates a mildly bullish trend on the monthly basis with no trend weekly. The On-Balance Volume is mildly bullish for both weekly and monthly periods.<BR><BR>In terms of performance, Krystal Biotech has outperformed the S&P 500 over the past week and month, with returns of 2.60% and 14.26% respectively, compared to -0.31% and 2.75% for the index. However, it has underperformed over the past year with a return of -5.94% against the S&P 500's 15.64%. Overall, the current technical stance is mildly bullish, driven by the weekly MACD, KST, and OBV indicators.

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Is Krystal Biotech, Inc. overvalued or undervalued?

11-Nov-2025

As of November 7, 2025, Krystal Biotech, Inc. is fairly valued with a P/E ratio of 27, an EV to EBITDA ratio of 23.83, and a PEG ratio of 0.25, showing strong growth potential, while outperforming peers like Halozyme Therapeutics and Elanco Animal Health, and achieving a year-to-date return of 27.36% compared to the S&P 500's 14.40%.

As of 7 November 2025, the valuation grade for Krystal Biotech, Inc. moved from expensive to fair. This suggests that the stock is currently fairly valued. Key valuation ratios include a P/E ratio of 27, an EV to EBITDA ratio of 23.83, and a PEG ratio of 0.25, indicating a strong growth potential relative to its price.<BR><BR>In comparison to its peers, Krystal Biotech's P/E ratio is higher than that of Halozyme Therapeutics, Inc., which has a P/E of 15.92, and significantly above Elanco Animal Health, Inc. at 19.25. Despite this, the company has demonstrated robust performance with a year-to-date return of 27.36%, significantly outpacing the S&P 500's return of 14.40% over the same period, reinforcing the notion that the stock is positioned well in the market.

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iScoreScore
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Strong Sell
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Strong Buy

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Dashboard
1

The company has declared Positive results for the last 7 consecutive quarters

  • OPERATING CASH FLOW(Y) Highest at USD 195.4 MM
  • NET PROFIT(HY) At USD 74.07 MM has Grown at 80.08%
  • ROCE(HY) Highest at 15.61%
2

High Institutional Holdings at 100%

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 4,203 Million (Small Cap)

stock-summary
P/E

27.00

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.65

stock-summary
Return on Equity

15.20%

stock-summary
Price to Book

4.04

Revenue and Profits:
Net Sales:
96 Million
(Quarterly Results - Jun 2025)
Net Profit:
38 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
47.78%
0%
47.78%
6 Months
69.55%
0%
69.55%
1 Year
19.35%
0%
19.35%
2 Years
108.88%
0%
108.88%
3 Years
186.4%
0%
186.4%
4 Years
225.88%
0%
225.88%
5 Years
313.72%
0%
313.72%

Krystal Biotech, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
224.57%
EBIT Growth (5y)
52.40%
EBIT to Interest (avg)
-32.99
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.63
Sales to Capital Employed (avg)
0.21
Tax Ratio
10.19%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
7.24%
ROE (avg)
4.74%
Valuation key factors
Factor
Value
P/E Ratio
27
Industry P/E
Price to Book Value
4.02
EV to EBIT
25.02
EV to EBITDA
23.83
EV to Capital Employed
9.05
EV to Sales
10.02
PEG Ratio
0.25
Dividend Yield
NA
ROCE (Latest)
36.18%
ROE (Latest)
14.98%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Bullish
Moving Averages
Bullish (Daily)
KST
Bullish
Mildly Bearish
Dow Theory
Bullish
Bullish
OBV
Bullish
Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 89 Schemes (55.76%)

Foreign Institutions

Held by 139 Foreign Institutions (12.15%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - YoY",
    "rhs": [
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        "prefix": "Net Sales ",
        "suffix": "YoY Growth in quarter ended Jun 2025 is 36.56% vs 0.00% in Jun 2024",
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        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in quarter ended Jun 2025 is 145.51% vs 146.99% in Jun 2024",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Jun'24",
        "Change(%)"
      ],
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          "field": "Net Sales",
          "val1": "96.00",
          "val2": "70.30",
          "chgp": "36.56%",
          "chgp_class": "positive"
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        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "40.90",
          "val2": "23.10",
          "chgp": "77.06%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
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          "chgp": "100.00%",
          "chgp_class": "positive"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "38.30",
          "val2": "15.60",
          "chgp": "145.51%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "409.30%",
          "val2": "299.70%",
          "chgp": "10.96%",
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        "prefix": "Consolidated Net Profit ",
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        "dir": 1
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        "Dec'24",
        "Dec'23",
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          "val2": "50.70",
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          "field": "Operating Profit (PBDIT) excl Other Income",
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          "field": "Interest",
          "val1": "0.00",
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          "field": "Exceptional Items",
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          "val2": "-12.50",
          "chgp": "-200.00%",
          "chgp_class": "negative"
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          "field": "Consolidate Net Profit",
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          "val2": "10.90",
          "chgp": "718.35%",
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          "field": "Operating Profit Margin (Excl OI)",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - YoYstock-summary
Jun'25
Jun'24
Change(%)
Net Sales
96.00
70.30
36.56%
Operating Profit (PBDIT) excl Other Income
40.90
23.10
77.06%
Interest
0.00
0.00
Exceptional Items
0.00
-12.50
100.00%
Consolidate Net Profit
38.30
15.60
145.51%
Operating Profit Margin (Excl OI)
409.30%
299.70%
10.96%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in quarter ended Jun 2025 is 36.56% vs 0.00% in Jun 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in quarter ended Jun 2025 is 145.51% vs 146.99% in Jun 2024

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
290.50
50.70
472.98%
Operating Profit (PBDIT) excl Other Income
109.90
-92.20
219.20%
Interest
0.00
0.00
Exceptional Items
-37.50
-12.50
-200.00%
Consolidate Net Profit
89.20
10.90
718.35%
Operating Profit Margin (Excl OI)
355.20%
-1,917.70%
227.29%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 472.98% vs 0.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 718.35% vs 107.79% in Dec 2023

stock-summaryCompany CV
About Krystal Biotech, Inc. stock-summary
stock-summary
Krystal Biotech, Inc.
Pharmaceuticals & Biotechnology
Krystal Biotech, Inc. is a gene therapy company. The Company is engaged in developing and commercializing novel treatments for patients suffering from dermatological diseases. The Company has developed a Skin TARgeted Delivery platform, or STAR-D platform, that consists of a patent pending engineered viral vector based on herpes simplex virus 1, or HSV-1, and skin-optimized gene transfer technology, to develop off-the-shelf treatments for dermatological diseases. The Company’s products include KB103 and KB104.The Company's KB103 is in preclinical development to treat dystrophic epidermolysis bullosa, or DEB, a rare and severe genetic disease. The Company's KB104 is to treat Netherton Syndrome, a severe form of ichthyosis, which is a family of genetic skin disorders associated with thickened scaly skin and characterized by chronic skin inflammation, itchiness and dehydration.
Company Coordinates stock-summary
Company Details
2100 Wharton St Ste 701 , PITTSBURGH PA : 15203-1973
stock-summary
Tel: 1 412 5865830
stock-summary
Registrar Details