Compare Krystal Biotech, Inc. with Similar Stocks
Dashboard
1
Poor Management Efficiency with a low ROE of 4.74%
- The company has been able to generate a Return on Equity (avg) of 4.74% signifying low profitability per unit of shareholders funds
2
With a growth in Net Sales of 17.52%, the company declared Very Positive results in Dec 25
3
With ROE of 16.80%, it has a very expensive valuation with a 6.00 Price to Book Value
4
High Institutional Holdings at 100%
5
Consistent Returns over the last 3 years
Stock DNA
Pharmaceuticals & Biotechnology
USD 7,313 Million (Small Cap)
36.00
NA
0.00%
-0.68
16.80%
6.00
Revenue and Profits:
Net Sales:
107 Million
(Quarterly Results - Dec 2025)
Net Profit:
51 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
1.46%
0%
1.46%
6 Months
57.38%
0%
57.38%
1 Year
31.12%
0%
31.12%
2 Years
52.4%
0%
52.4%
3 Years
227.32%
0%
227.32%
4 Years
287.64%
0%
287.64%
5 Years
268.48%
0%
268.48%
Krystal Biotech, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
229.79%
EBIT Growth (5y)
47.08%
EBIT to Interest (avg)
-32.99
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.63
Sales to Capital Employed (avg)
0.23
Tax Ratio
10.19%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
7.24%
ROE (avg)
4.74%
Valuation key factors
Factor
Value
P/E Ratio
36
Industry P/E
Price to Book Value
6.00
EV to EBIT
40.26
EV to EBITDA
38.69
EV to Capital Employed
16.48
EV to Sales
16.67
PEG Ratio
0.57
Dividend Yield
NA
ROCE (Latest)
40.94%
ROE (Latest)
16.80%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bearish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
Mildly Bearish
Bullish
OBV
Mildly Bearish
Mildly Bearish
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 85 Schemes (55.03%)
Foreign Institutions
Held by 157 Foreign Institutions (10.85%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - YoY
Dec'25
Dec'24
Change(%)
Net Sales
107.10
91.10
17.56%
Operating Profit (PBDIT) excl Other Income
46.00
43.00
6.98%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
51.40
45.50
12.97%
Operating Profit Margin (Excl OI)
413.30%
454.00%
-4.07%
USD in Million.
Net Sales
YoY Growth in quarter ended Dec 2025 is 17.56% vs 116.39% in Dec 2024
Consolidated Net Profit
YoY Growth in quarter ended Dec 2025 is 12.97% vs 422.99% in Dec 2024
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
389.10
290.50
33.94%
Operating Profit (PBDIT) excl Other Income
167.80
109.90
52.68%
Interest
0.00
0.00
Exceptional Items
0.00
-37.50
100.00%
Consolidate Net Profit
204.80
89.20
129.60%
Operating Profit Margin (Excl OI)
414.50%
355.20%
5.93%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 33.94% vs 472.98% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 129.60% vs 718.35% in Dec 2024
About Krystal Biotech, Inc. 
Krystal Biotech, Inc.
Pharmaceuticals & Biotechnology
Krystal Biotech, Inc. is a gene therapy company. The Company is engaged in developing and commercializing novel treatments for patients suffering from dermatological diseases. The Company has developed a Skin TARgeted Delivery platform, or STAR-D platform, that consists of a patent pending engineered viral vector based on herpes simplex virus 1, or HSV-1, and skin-optimized gene transfer technology, to develop off-the-shelf treatments for dermatological diseases. The Company’s products include KB103 and KB104.The Company's KB103 is in preclinical development to treat dystrophic epidermolysis bullosa, or DEB, a rare and severe genetic disease. The Company's KB104 is to treat Netherton Syndrome, a severe form of ichthyosis, which is a family of genetic skin disorders associated with thickened scaly skin and characterized by chronic skin inflammation, itchiness and dehydration.
Company Coordinates 
Company Details
2100 Wharton St Ste 701 , PITTSBURGH PA : 15203-1973
Registrar Details






