AC Immune SA

  • Market Cap: Micro Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: CH0329023102
USD
2.88
0.11 (3.97%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

137.93 k

Shareholding (Mar 2025)

FII

2.25%

Held by 29 FIIs

DII

96.38%

Held by 4 DIIs

Promoter

0.00%

How big is AC Immune SA?

22-Jun-2025

As of Jun 18, AC Immune SA has a market capitalization of 201.92 million and reported net sales of 32.57 million with a net profit of -57.98 million over the latest four quarters. Shareholder's funds are 123.88 million, and total assets amount to 254.80 million.

As of Jun 18, AC Immune SA has a market capitalization of 201.92 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the sum of net sales for the latest four quarters is 32.57 million, while the sum of net profit for the same period is -57.98 million.<BR><BR>As of Dec 24, the shareholder's funds are reported at 123.88 million, and total assets amount to 254.80 million.

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What does AC Immune SA do?

22-Jun-2025

AC Immune SA is a Switzerland-based biopharmaceutical company focused on precision medicine for neurodegenerative diseases. As of March 2025, it reported net sales of $1 million and a net loss of $21 million, with a market cap of $201.92 million.

Overview:<BR>AC Immune SA is a Switzerland-based clinical-stage biopharmaceutical company focused on precision medicine for neurodegenerative diseases within the Pharmaceuticals & Biotechnology industry.<BR><BR>Financial Snapshot:<BR>- Most recent Net Sales: 1 Million (Quarterly Results - Mar 2025)<BR>- Most recent Net Profit: -21 Million (Quarterly Results - Mar 2025)<BR>- Market cap: USD 201.92 Million (Micro Cap)<BR><BR>Key Metrics:<BR>- P/E: NA (Loss Making)<BR>- Industry P/E: NA<BR>- Dividend Yield: 0.00%<BR>- Debt Equity: -1.53<BR>- Return on Equity: -54.12%<BR>- Price to Book: 1.88<BR><BR>Contact Details:<BR>- Address: EPFL Innovation Park, Building B, LAUSANNE None: 1015<BR>- Tel: ['41 21 3459121', '41 21 3459121']<BR>- Fax: 41 21 3459120<BR>- Website: https://www.acimmune.com/

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Who are in the management team of AC Immune SA?

22-Jun-2025

As of March 2022, the management team of AC Immune SA includes Dr. Douglas Williams (Non-Executive Independent Chairman), Prof. Dr. Andrea Pfeifer (CEO and Co-Founder), Mr. Martin Velasco (Non-Executive Independent Vice Chairman), and several Non-Executive Independent Directors: Dr. Peter Bollmann, Mr. Thomas Graney, and Dr. Werner Lanthaler. This team oversees the company's strategic direction and governance.

As of March 2022, the management team of AC Immune SA includes the following individuals:<BR><BR>- Dr. Douglas Williams, who serves as the Non-Executive Independent Chairman of the Board.<BR>- Prof. Dr. Andrea Pfeifer, who is the Chief Executive Officer, Co-Founder, and Director.<BR>- Mr. Martin Velasco, who holds the position of Non-Executive Independent Vice Chairman of the Board.<BR>- Dr. Peter Bollmann, who is a Non-Executive Independent Director.<BR>- Mr. Thomas Graney, also a Non-Executive Independent Director.<BR>- Dr. Werner Lanthaler, who serves as a Non-Executive Independent Director. <BR><BR>This team is responsible for guiding the company's strategic direction and governance.

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Should I buy, sell or hold AC Immune SA?

22-Jun-2025

Is AC Immune SA overvalued or undervalued?

20-Sep-2025

As of March 14, 2024, AC Immune SA is considered risky and overvalued due to negative earnings and significant losses, reflected in its financial ratios, and has underperformed the market with a return of -30.58% over the past year.

As of 14 March 2024, the valuation grade for AC Immune SA has moved from does not qualify to risky, indicating a shift in perception towards the company's financial health. The company appears to be overvalued, given its negative earnings and significant losses reflected in key ratios. The price-to-book value stands at 2.00, while the EV to EBITDA and EV to EBIT ratios are both negative at -0.93 and -0.89, respectively, highlighting the challenges in generating positive cash flows.<BR><BR>In comparison with peers, AC Immune SA's P/E ratio is not applicable due to its loss-making status, while Lexicon Pharmaceuticals has a P/E of -3.53 and Vanda Pharmaceuticals has a P/E of -4.02, indicating that AC Immune is not alone in facing valuation challenges within this sector. Over the past year, AC Immune SA has underperformed significantly, with a return of -30.58% compared to the S&P 500's 17.14%, reinforcing the notion that the stock may be overvalued relative to its peers and the broader market.

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Is AC Immune SA technically bullish or bearish?

20-Sep-2025

As of June 4, 2025, AC Immune SA shows a mildly bearish trend with mixed signals across time frames, having outperformed the S&P 500 in the short term but significantly underperformed over the past year.

As of 4 June 2025, the technical trend for AC Immune SA has changed from bearish to mildly bearish. The current stance is mildly bearish, driven by daily moving averages indicating a bearish sentiment, while the weekly MACD and Bollinger Bands show bullish signals. However, the monthly MACD and KST are bearish, suggesting mixed signals across different time frames. The Dow Theory indicates a mildly bullish stance on both weekly and monthly charts, while the On-Balance Volume (OBV) also reflects a mildly bullish trend.<BR><BR>In terms of performance, AC Immune has outperformed the S&P 500 over the past week and month, with returns of 5.88% and 17.21% respectively, but it has significantly underperformed over longer periods, including a -30.58% return over the past year compared to the S&P 500's 17.14%.

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iScoreScore
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Strong Sell
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Dashboard
1

With a fall in Net Sales of -80.58%, the company declared Very Negative results in Jun 25

  • The company has declared negative results in Mar 25 after 2 consecutive negative quarters
  • NET SALES(9M) At USD 3.98 MM has Grown at -77.19%
  • INTEREST(HY) At USD 0.12 MM has Grown at 53.12%
  • ROCE(HY) Lowest at -50.57%
2

Risky - Negative EBITDA

3

Consistent Underperformance against the benchmark over the last 3 years

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 231 Million (Micro Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-1.69

stock-summary
Return on Equity

-62.27%

stock-summary
Price to Book

2.46

Revenue and Profits:
Net Sales:
2 Million
(Quarterly Results - Jun 2025)
Net Profit:
-26 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
27.43%
0%
27.43%
6 Months
74.55%
0%
74.55%
1 Year
-10.28%
0%
-10.28%
2 Years
-15.29%
0%
-15.29%
3 Years
12.06%
0%
12.06%
4 Years
-40.62%
0%
-40.62%
5 Years
-46.77%
0%
-46.77%

AC Immune SA for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
-7.42%
EBIT Growth (5y)
-181.27%
EBIT to Interest (avg)
-69.76
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.53
Sales to Capital Employed (avg)
0.16
Tax Ratio
0.01%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
29.34%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
2.00
EV to EBIT
-0.89
EV to EBITDA
-0.93
EV to Capital Employed
-0.91
EV to Sales
1.57
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-54.12%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bullish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Bullish
Bearish
Dow Theory
Mildly Bearish
No Trend
OBV
No Trend
Mildly Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Foreign Institutions

Domestic Funds

Held in 10 Schemes (1.37%)

Foreign Institutions

Held by 29 Foreign Institutions (2.25%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 45.45% vs -15.38% in Mar 2025",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -21.23% vs -17.78% in Mar 2025",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "1.60",
          "val2": "1.10",
          "chgp": "45.45%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-22.80",
          "val2": "-20.90",
          "chgp": "-9.09%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "0.10",
          "val2": "0.10",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Exceptional Items",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-25.70",
          "val2": "-21.20",
          "chgp": "-21.23%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-14,866.80%",
          "val2": "-19,564.60%",
          "chgp": "469.78%",
          "chgp_class": "positive"
        }
      ]
    }
  },
  {
    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'24",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in year ended Dec 2024 is 87.88% vs 302.44% in Dec 2023",
        "dir": -1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is 4.15% vs 18.62% in Dec 2023",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
        "Change(%)"
      ],
      "body": [
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          "field": "Net Sales",
          "val1": "31.00",
          "val2": "16.50",
          "chgp": "87.88%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-57.20",
          "val2": "-58.90",
          "chgp": "2.89%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "0.20",
          "val2": "0.20",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Exceptional Items",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-57.80",
          "val2": "-60.30",
          "chgp": "4.15%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-1,923.20%",
          "val2": "-3,723.40%",
          "chgp": "180.02%",
          "chgp_class": "positive"
        }
      ]
    }
  }
]
Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
1.60
1.10
45.45%
Operating Profit (PBDIT) excl Other Income
-22.80
-20.90
-9.09%
Interest
0.10
0.10
Exceptional Items
0.00
0.00
Consolidate Net Profit
-25.70
-21.20
-21.23%
Operating Profit Margin (Excl OI)
-14,866.80%
-19,564.60%
469.78%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 45.45% vs -15.38% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -21.23% vs -17.78% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
31.00
16.50
87.88%
Operating Profit (PBDIT) excl Other Income
-57.20
-58.90
2.89%
Interest
0.20
0.20
Exceptional Items
0.00
0.00
Consolidate Net Profit
-57.80
-60.30
4.15%
Operating Profit Margin (Excl OI)
-1,923.20%
-3,723.40%
180.02%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 87.88% vs 302.44% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 4.15% vs 18.62% in Dec 2023

stock-summaryCompany CV
About AC Immune SA stock-summary
stock-summary
AC Immune SA
Pharmaceuticals & Biotechnology
AC Immune SA is a Switzerland-based clinical-stage biopharmaceutical company. The Company focuses on precision medicine for neurodegenerative diseases. It designs, discovers and develops therapeutic, as well as diagnostic products for prevention, diagnosis and treatment of diseases caused by misfolding proteins. Its SupraAntigen and Morphomer technology platforms to create antibodies, small molecules and vaccines designed to address a broad range of neurodegenerative indications, such as Alzheimer's disease (AD). The Company's pipeline includes nine therapeutic product candidates with five in clinical trials, and three diagnostic candidates. Its lead product candidate is Crenezumab, a humanized and monoclonal anti-Abeta antibody for Alzheimer’s disease. It has collaborations with pharmaceutical companies, including Roche/Genentech, Eli Lilly, Biogen, Janssen Pharmaceuticals, Nestle Institute of Health Sciences, Life Molecular Imaging (formerly Piramal Imaging) and Essex Bio-Technology.
Company Coordinates stock-summary
Company Details
EPFL Innovation Park, Building B , LAUSANNE None : 1015
stock-summary
Tel: 41 21 345912141 21 3459121
stock-summary
Registrar Details