Compare Agios Pharmaceuticals, Inc. with Similar Stocks
Dashboard
1
Poor Management Efficiency with a low ROE of 9.08%
- The company has been able to generate a Return on Equity (avg) of 9.08% signifying low profitability per unit of shareholders funds
2
Poor long term growth as Net Sales has grown by an annual rate of -26.13% and Operating profit at -7.55% over the last 5 years
3
The company has declared negative results in Mar'2025 after 2 consecutive positive quarters
4
Risky -
5
Below par performance in long term as well as near term
Stock DNA
Pharmaceuticals & Biotechnology
USD 1,584 Million (Small Cap)
4.00
NA
0.00%
-0.73
-31.24%
1.23
Revenue and Profits:
Net Sales:
12 Million
(Quarterly Results - Jun 2025)
Net Profit:
-112 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-33.58%
0%
-33.58%
6 Months
-26.52%
0%
-26.52%
1 Year
-21.88%
0%
-21.88%
2 Years
15.07%
0%
15.07%
3 Years
-12.02%
0%
-12.02%
4 Years
-7.55%
0%
-7.55%
5 Years
-47.38%
0%
-47.38%
Agios Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
-26.13%
EBIT Growth (5y)
-7.55%
EBIT to Interest (avg)
-324.10
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.60
Sales to Capital Employed (avg)
0.03
Tax Ratio
6.23%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
9.08%
Valuation key factors
Factor
Value
P/E Ratio
4
Industry P/E
Price to Book Value
1.73
EV to EBIT
-3.76
EV to EBITDA
-3.81
EV to Capital Employed
2.80
EV to Sales
44.67
PEG Ratio
0.01
Dividend Yield
NA
ROCE (Latest)
-74.58%
ROE (Latest)
45.41%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bearish
Bearish
RSI
No Signal
Bullish
Bollinger Bands
Mildly Bearish
Mildly Bearish
Moving Averages
Mildly Bearish (Daily)
KST
Bearish
Bearish
Dow Theory
Mildly Bullish
No Trend
OBV
No Trend
No Trend
Shareholding Snapshot : Sep 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 58 Schemes (36.24%)
Foreign Institutions
Held by 110 Foreign Institutions (26.0%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ
Jun'25
Mar'25
Change(%)
Net Sales
12.50
8.70
43.68%
Operating Profit (PBDIT) excl Other Income
-125.80
-105.40
-19.35%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-112.00
-89.30
-25.42%
Operating Profit Margin (Excl OI)
-10,201.20%
-12,219.70%
201.85%
USD in Million.
Net Sales
QoQ Growth in quarter ended Jun 2025 is 43.68% vs -18.69% in Mar 2025
Consolidated Net Profit
QoQ Growth in quarter ended Jun 2025 is -25.42% vs 7.46% in Mar 2025
Annual Results Snapshot (Consolidated) - Dec'24
Dec'24
Dec'23
Change(%)
Net Sales
36.50
26.80
36.19%
Operating Profit (PBDIT) excl Other Income
-420.10
-384.90
-9.15%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
673.70
-352.10
291.34%
Operating Profit Margin (Excl OI)
-11,664.70%
-14,595.20%
293.05%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2024 is 36.19% vs 88.73% in Dec 2023
Consolidated Net Profit
YoY Growth in year ended Dec 2024 is 291.34% vs -51.90% in Dec 2023
About Agios Pharmaceuticals, Inc. 
Agios Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Agios Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company's therapeutic areas of focus are cancer and rare genetic metabolic disorders, which are a group of over 600 rare genetic diseases caused by mutations, or defects, of single metabolic genes. The Company's cancer product candidates are enasidenib and ivosidenib (AG-120), which target mutated isocitrate dehydrogenase 2 (IDH2) and isocitrate dehydrogenase 1 (IDH1), respectively, and AG-881, which targets both mutated IDH1 and mutated IDH2. These mutations are found in a range of hematological malignancies and solid tumors. The lead product candidate in its rare genetic metabolic disorder (RGD), programs, AG-348, targets pyruvate kinase-R for the treatment of pyruvate kinase deficiency. Pyruvate kinase deficiency is a rare disorder that often results in severe hemolytic anemia due to inherited mutations in the pyruvate kinase enzyme within red blood cells.
Company Coordinates 
Company Details
88 Sidney St , CAMBRIDGE MA : 02139-4137
Registrar Details






