Agios Pharmaceuticals, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US00847X1046
USD
27.42
0.44 (1.63%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.23 M

Shareholding (Mar 2025)

FII

28.39%

Held by 110 FIIs

DII

26.74%

Held by 50 DIIs

Promoter

2.71%

How big is Agios Pharmaceuticals, Inc.?

22-Jun-2025

As of Jun 18, Agios Pharmaceuticals, Inc. has a market capitalization of $2.56 billion, with net sales of $37.04 million and a net profit of $665.98 million over the latest four quarters.

Market Cap: As of Jun 18, Agios Pharmaceuticals, Inc. has a market capitalization of 2,557.19 million, categorizing it as a Small Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Agios Pharmaceuticals, Inc. reported net sales of 37.04 million and a net profit of 665.98 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 1,540.96 million and total assets of 1,663.20 million.

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What does Agios Pharmaceuticals, Inc. do?

22-Jun-2025

Agios Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for cancer and rare genetic metabolic disorders. As of March 2025, it reported net sales of $9 million and a net loss of $89 million, with a market cap of $2.56 billion.

Overview:<BR>Agios Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for cancer and rare genetic metabolic disorders within the Pharmaceuticals & Biotechnology industry.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 9 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -89 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 2,557.19 Million (Small Cap)<BR><BR>Key Metrics:<BR>P/E: 4.00 <BR>Dividend Yield: 0.00% <BR>Debt Equity: -0.60 <BR>Return on Equity: 45.41% <BR>Price to Book: 1.74<BR><BR>Contact Details:<BR>Address: 88 Sidney St, CAMBRIDGE MA: 02139-4137 <BR>Tel: ['1 617 6498600', '1 617 844-6630'] <BR>Fax: 1 302 6555049 <BR>Website: http://www.agios.com/

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Who are in the management team of Agios Pharmaceuticals, Inc.?

22-Jun-2025

As of March 2022, the management team of Agios Pharmaceuticals, Inc. includes Dr. David Schenkein (Executive Chairman), Dr. Jacqualyn Fouse (CEO), Dr. David Scadden, and independent directors Paul Clancy, Ian Clark, Kaye Foster, and Maykin Ho. They are responsible for the company's strategic direction and operations.

As of March 2022, the management team of Agios Pharmaceuticals, Inc. includes the following individuals:<BR><BR>- Dr. David Schenkein, who serves as the Executive Chairman of the Board.<BR>- Dr. Jacqualyn Fouse, who is the Chief Executive Officer and a Director.<BR>- Dr. David Scadden, who is a Director.<BR>- Mr. Paul Clancy, who is an Independent Director.<BR>- Mr. Ian Clark, who is also an Independent Director.<BR>- Ms. Kaye Foster, who serves as an Independent Director.<BR>- Dr. Maykin Ho, who is another Independent Director.<BR><BR>This team plays a crucial role in guiding the company's strategic direction and operations.

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Should I buy, sell or hold Agios Pharmaceuticals, Inc.?

22-Jun-2025

Is Agios Pharmaceuticals, Inc. technically bullish or bearish?

07-Oct-2025

As of October 3, 2025, Agios Pharmaceuticals shows a bullish technical trend with strong momentum indicators, outperforming the S&P 500 in the short term, though it has underperformed over the long term.

As of 3 October 2025, the technical trend for Agios Pharmaceuticals, Inc. has changed from mildly bullish to bullish. The weekly and monthly MACD indicators are both bullish, and the monthly RSI is also bullish, indicating strong momentum. Bollinger Bands are bullish on both weekly and monthly time frames, further supporting the bullish stance. Daily moving averages are bullish as well. However, the KST shows a mildly bearish signal on both weekly and monthly time frames, and Dow Theory indicates a mildly bullish trend on a monthly basis. <BR><BR>In terms of performance, Agios has outperformed the S&P 500 over the past week and month, with returns of 4.13% and 13.55% respectively, compared to 1.09% and 4.15% for the index. However, over the longer term, the stock has underperformed the S&P 500 on a 1-year, 3-year, 5-year, and 10-year basis. Overall, the current technical stance is bullish, with strong indicators supporting this view.

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Is Agios Pharmaceuticals, Inc. overvalued or undervalued?

21-Oct-2025

As of October 17, 2025, Agios Pharmaceuticals, Inc. is considered attractive due to its undervalued status, reflected in a low P/E ratio of 4, a PEG ratio of 0.01, and strong year-to-date returns of 28.82%, outperforming the S&P 500.

As of 17 October 2025, the valuation grade for Agios Pharmaceuticals, Inc. has changed from very attractive to attractive, indicating a shift in market perception. The company appears to be undervalued, with a P/E ratio of 4, a PEG ratio of 0.01, and an EV to EBITDA ratio of -3.81, which suggests that the stock may be trading at a significant discount relative to its earnings potential. <BR><BR>In comparison to its peers, Agios has a lower P/E ratio than PTC Therapeutics, Inc. at 5.85 and Crinetics Pharmaceuticals, Inc. at -8.95, indicating that it is relatively cheaper in terms of earnings. The company's return performance shows a 1-week return of 4.24% compared to the S&P 500's 1.70%, and a year-to-date return of 28.82% against the S&P 500's 13.30%, which reinforces the notion that the stock may be undervalued.

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iScoreScore
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Strong Sell
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Strong Buy

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Dashboard
1

Poor Management Efficiency with a low ROE of 9.08%

  • The company has been able to generate a Return on Equity (avg) of 9.08% signifying low profitability per unit of shareholders funds
2

Poor long term growth as Net Sales has grown by an annual rate of -26.13% and Operating profit at -7.55% over the last 5 years

 
3

The company has declared negative results in Mar'2025 after 2 consecutive positive quarters

4

Risky -

5

Below par performance in long term as well as near term

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 2,691 Million (Small Cap)

stock-summary
P/E

4.00

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.67

stock-summary
Return on Equity

47.47%

stock-summary
Price to Book

1.96

Revenue and Profits:
Net Sales:
12 Million
(Quarterly Results - Jun 2025)
Net Profit:
-112 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-32.48%
0%
-32.48%
6 Months
-17.83%
0%
-17.83%
1 Year
-53.43%
0%
-53.43%
2 Years
19.74%
0%
19.74%
3 Years
-13.01%
0%
-13.01%
4 Years
-19.87%
0%
-19.87%
5 Years
-39.4%
0%
-39.4%

Agios Pharmaceuticals, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
-26.13%
EBIT Growth (5y)
-7.55%
EBIT to Interest (avg)
-324.10
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.60
Sales to Capital Employed (avg)
0.03
Tax Ratio
6.23%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
9.08%
Valuation key factors
Factor
Value
P/E Ratio
4
Industry P/E
Price to Book Value
1.73
EV to EBIT
-3.76
EV to EBITDA
-3.81
EV to Capital Employed
2.80
EV to Sales
44.67
PEG Ratio
0.01
Dividend Yield
NA
ROCE (Latest)
-74.58%
ROE (Latest)
45.41%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bearish
Mildly Bearish
RSI
Bullish
Bullish
Bollinger Bands
Mildly Bearish
Bearish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Mildly Bearish
Dow Theory
No Trend
No Trend
OBV
No Trend
No Trend
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 60 Schemes (42.14%)

Foreign Institutions

Held by 110 Foreign Institutions (28.39%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 43.68% vs -18.69% in Mar 2025",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -25.42% vs 7.46% in Mar 2025",
        "dir": -1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "12.50",
          "val2": "8.70",
          "chgp": "43.68%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-125.80",
          "val2": "-105.40",
          "chgp": "-19.35%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
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          "field": "Exceptional Items",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-112.00",
          "val2": "-89.30",
          "chgp": "-25.42%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-10,201.20%",
          "val2": "-12,219.70%",
          "chgp": "201.85%",
          "chgp_class": "positive"
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    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'24",
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        "prefix": "Net Sales ",
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      },
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        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is 291.34% vs -51.90% in Dec 2023",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
        "Change(%)"
      ],
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          "field": "Net Sales",
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          "val2": "26.80",
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        {
          "field": "Operating Profit (PBDIT) excl Other Income",
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          "field": "Interest",
          "val1": "0.00",
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          "chgp": "",
          "chgp_class": "neutral"
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          "field": "Exceptional Items",
          "val1": "0.00",
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          "chgp": "",
          "chgp_class": "neutral"
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          "field": "Consolidate Net Profit",
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          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-11,664.70%",
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          "chgp_class": "positive"
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
12.50
8.70
43.68%
Operating Profit (PBDIT) excl Other Income
-125.80
-105.40
-19.35%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-112.00
-89.30
-25.42%
Operating Profit Margin (Excl OI)
-10,201.20%
-12,219.70%
201.85%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 43.68% vs -18.69% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -25.42% vs 7.46% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
36.50
26.80
36.19%
Operating Profit (PBDIT) excl Other Income
-420.10
-384.90
-9.15%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
673.70
-352.10
291.34%
Operating Profit Margin (Excl OI)
-11,664.70%
-14,595.20%
293.05%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 36.19% vs 88.73% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 291.34% vs -51.90% in Dec 2023

stock-summaryCompany CV
About Agios Pharmaceuticals, Inc. stock-summary
stock-summary
Agios Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Agios Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company. The Company's therapeutic areas of focus are cancer and rare genetic metabolic disorders, which are a group of over 600 rare genetic diseases caused by mutations, or defects, of single metabolic genes. The Company's cancer product candidates are enasidenib and ivosidenib (AG-120), which target mutated isocitrate dehydrogenase 2 (IDH2) and isocitrate dehydrogenase 1 (IDH1), respectively, and AG-881, which targets both mutated IDH1 and mutated IDH2. These mutations are found in a range of hematological malignancies and solid tumors. The lead product candidate in its rare genetic metabolic disorder (RGD), programs, AG-348, targets pyruvate kinase-R for the treatment of pyruvate kinase deficiency. Pyruvate kinase deficiency is a rare disorder that often results in severe hemolytic anemia due to inherited mutations in the pyruvate kinase enzyme within red blood cells.
Company Coordinates stock-summary
Company Details
88 Sidney St , CAMBRIDGE MA : 02139-4137
stock-summary
Tel: 1 617 64986001 617 844-6630
stock-summary
Registrar Details