Alnylam Pharmaceuticals, Inc.

  • Market Cap: Large Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US02043Q1076
USD
357.98
53.98 (17.76%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

434.11 k

Shareholding (Sep 2025)

FII

19.71%

Held by 367 FIIs

DII

16.11%

Held by 75 DIIs

Promoter

4.04%

How big is Alnylam Pharmaceuticals, Inc.?

22-Jun-2025

As of Jun 18, Alnylam Pharmaceuticals, Inc. has a market capitalization of $40.25 billion, with recent net sales of $2.35 billion and a net profit of -$269.70 million.

Market Cap: As of Jun 18, Alnylam Pharmaceuticals, Inc. has a market capitalization of 40,252.20 million, categorizing it as a Mid Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Alnylam Pharmaceuticals, Inc. reported net sales of 2,348.11 million and a net profit of -269.70 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 67.09 million and total assets of 4,301.82 million.

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What does Alnylam Pharmaceuticals, Inc. do?

22-Jun-2025

Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing RNA interference therapeutics, with recent net sales of $594 million and a market cap of approximately $40.25 billion. The company is currently operating at a loss, with a net profit of -$57 million.

Overview: <BR>Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company engaged in the discovery, development, and commercialization of ribonucleic acid (RNA) interference (RNAi) therapeutics, operating within the Pharmaceuticals & Biotechnology industry and classified as a mid-cap company.<BR><BR>Financial Snapshot: <BR>Most recent Net Sales: 594 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -57 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 40,252.20 Million (Mid Cap)<BR><BR>Key Metrics: <BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.21 <BR>Return on Equity: -42.12% <BR>Price to Book: 348.70<BR><BR>Contact Details: <BR>Address: 675 W Kendall St, CAMBRIDGE MA: 02142-1168 <BR>Tel: 1 617 5518200 <BR>Fax: 1 617 5518101 <BR>Website: https://www.alnylam.com/

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Who are in the management team of Alnylam Pharmaceuticals, Inc.?

22-Jun-2025

As of March 2022, the management team of Alnylam Pharmaceuticals, Inc. includes CEO Dr. John Maraganore and Independent Chairman Mr. Michael Bonney, along with several independent directors such as Dr. Margaret Hamburg and Dr. Steven Paul. This team provides governance and strategic direction for the company.

As of March 2022, the management team of Alnylam Pharmaceuticals, Inc. includes the following individuals:<BR><BR>- Mr. Michael Bonney, Independent Chairman of the Board<BR>- Dr. John Maraganore, Chief Executive Officer and Director<BR>- Mr. Olivier Brandicourt, Director<BR>- Dr. Dennis Ausiello, Independent Director<BR>- Ms. Marsha Fanucci, Independent Director<BR>- Dr. Margaret Hamburg, Independent Director<BR>- Dr. Steven Paul, Independent Director<BR><BR>This team comprises a mix of executive leadership and independent directors, contributing to the governance and strategic direction of the company.

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Should I buy, sell or hold Alnylam Pharmaceuticals, Inc.?

22-Jun-2025

Is Alnylam Pharmaceuticals, Inc. technically bullish or bearish?

05-Nov-2025

As of October 31, 2025, Alnylam Pharmaceuticals has a mildly bullish technical trend, supported by monthly indicators and daily moving averages, despite some bearish signals in the weekly timeframe, and it has significantly outperformed the S&P 500 year-to-date and over the past three years.

As of 31 October 2025, the technical trend for Alnylam Pharmaceuticals, Inc. has changed from bullish to mildly bullish. The weekly MACD and KST indicators are mildly bearish, while the monthly MACD and KST are bullish. The Bollinger Bands show a mildly bullish stance on both weekly and monthly time frames, and daily moving averages are also mildly bullish. However, Dow Theory indicates a mildly bearish trend on both weekly and monthly bases. <BR><BR>In terms of performance, Alnylam has significantly outperformed the S&P 500 year-to-date with a return of 79.96% compared to 16.30%, and over the past three years, it has returned 96.31% versus the S&P 500's 76.66%. Overall, the current technical stance is mildly bullish, supported by the monthly indicators and daily moving averages, despite some bearish signals in the weekly timeframe.

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Dashboard

1

With a growth in Net Sales of 30.21%, the company declared Outstanding results in Jun 25

  • NET PROFIT(HY) Higher at USD -49.61 MM
  • INVENTORY TURNOVER RATIO(HY) Highest at 5.17 times
  • CASH AND EQV(HY) Highest at USD 5,489.81 MM
2

Market Beating Performance

stock-summaryMojo Parameters

Mojo Parameters

Stock DNA

stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 48,282 Million (Large Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.75

stock-summary
Return on Equity

124.75%

stock-summary
Price to Book

206.43

Revenue and Profits:
Net Sales:
1,249 Million
(Quarterly Results - Sep 2025)
Net Profit:
251 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
53.59%
0%
53.59%
6 Months
40.99%
0%
40.99%
1 Year
133.26%
0%
133.26%
2 Years
87.59%
0%
87.59%
3 Years
170.97%
0%
170.97%
4 Years
119.27%
0%
119.27%
5 Years
175.98%
0%
175.98%

Alnylam Pharmaceuticals, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions

News

Announcements stock-summary

Icon
No announcement available

Corporate Actions stock-summary

Icon
No corporate action available
stock-summaryKey Factors

Quality key factors stock-summary

Factor
Value
Sales Growth (5y)
48.13%
EBIT Growth (5y)
12.54%
EBIT to Interest (avg)
-3.79
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.21
Sales to Capital Employed (avg)
0.87
Tax Ratio
24.11%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0

Valuation key factors

Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
339.80
EV to EBIT
-338.77
EV to EBITDA
-676.03
EV to Capital Employed
-1589.07
EV to Sales
16.65
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-42.12%

Technicals key factors

Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
Bullish
No Signal
Bollinger Bands
Bearish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Bearish
Bullish
Dow Theory
Mildly Bearish
Mildly Bearish
OBV
No Trend
Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Sep 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 123 Schemes (60.13%)

Foreign Institutions

Held by 367 Foreign Institutions (19.71%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Sep'25 - QoQ",
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        "prefix": "Consolidated Net Profit ",
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          "val2": "-2.30",
          "chgp": "16,700.00%",
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          "field": "Interest",
          "val1": "44.40",
          "val2": "40.20",
          "chgp": "10.45%",
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          "val2": "-15.30",
          "chgp": "-578.43%",
          "chgp_class": "negative"
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          "field": "Consolidate Net Profit",
          "val1": "251.10",
          "val2": "-66.30",
          "chgp": "478.73%",
          "chgp_class": "positive"
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        {
          "field": "Operating Profit Margin (Excl OI)",
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          "val2": "-20.90%",
          "chgp": "31.55%",
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        "Dec'24",
        "Dec'23",
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          "chgp": "17.08%",
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          "val1": "-170.80",
          "val2": "-91.00",
          "chgp": "-87.69%",
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          "chgp": "36.80%",
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          "field": "Operating Profit Margin (Excl OI)",
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Quarterly Results Snapshot (Consolidated) - Sep'25 - QoQstock-summary

Sep'25
Jun'25
Change(%)
Net Sales
1,249.00
773.70
61.43%
Operating Profit (PBDIT) excl Other Income
381.80
-2.30
16,700.00%
Interest
44.40
40.20
10.45%
Exceptional Items
-103.80
-15.30
-578.43%
Consolidate Net Profit
251.10
-66.30
478.73%
Operating Profit Margin (Excl OI)
294.60%
-20.90%
31.55%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Sep 2025 is 61.43% vs 30.21% in Jun 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Sep 2025 is 478.73% vs -15.30% in Jun 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary

Dec'24
Dec'23
Change(%)
Net Sales
2,248.20
1,828.30
22.97%
Operating Profit (PBDIT) excl Other Income
-120.20
-228.10
47.30%
Interest
141.90
121.20
17.08%
Exceptional Items
-170.80
-91.00
-87.69%
Consolidate Net Profit
-278.20
-440.20
36.80%
Operating Profit Margin (Excl OI)
-78.70%
-154.30%
7.56%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 22.97% vs 76.24% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 36.80% vs 61.09% in Dec 2023

stock-summaryCompany CV
About Alnylam Pharmaceuticals, Inc. stock-summary
stock-summary
Alnylam Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is engaged in the discovery, development and commercialization of ribonucleic acid (RNA) interference (RNAi) therapeutics. The Company is focused on the use of its N-acetylgalactosamine (GalNAc)-conjugate platform for delivery of small interfering RNAs (siRNAs). Its pipeline of investigational RNAi therapeutics focuses on three Strategic Therapeutic Areas (STArs): Genetic Medicines, with multiple product candidates for the treatment of rare diseases; Cardio-Metabolic Diseases, with product candidates directed toward genetically validated, liver-expressed disease targets for unmet needs in cardiovascular and metabolic diseases, and Hepatic Infectious Diseases, with product candidates designed to address the global health challenges of hepatic infectious diseases, beginning with hepatitis B and hepatitis D viral infections.
Company Coordinates stock-summary
Company Details
675 W Kendall St , CAMBRIDGE MA : 02142-1168
stock-summary
Tel: 1 617 5518200
stock-summary
Registrar Details