Compare Alnylam Pharmaceuticals, Inc. with Similar Stocks
Stock DNA
Pharmaceuticals & Biotechnology
USD 48,282 Million (Large Cap)
NA (Loss Making)
NA
0.00%
-0.75
124.75%
206.43
Revenue and Profits:
Net Sales:
1,249 Million
(Quarterly Results - Sep 2025)
Net Profit:
251 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-25.5%
0%
-25.5%
6 Months
-23.35%
0%
-23.35%
1 Year
17.94%
0%
17.94%
2 Years
90.59%
0%
90.59%
3 Years
46.41%
0%
46.41%
4 Years
125.66%
0%
125.66%
5 Years
98.75%
0%
98.75%
Alnylam Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
48.13%
EBIT Growth (5y)
12.54%
EBIT to Interest (avg)
-3.79
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.21
Sales to Capital Employed (avg)
0.87
Tax Ratio
24.11%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
339.80
EV to EBIT
-338.77
EV to EBITDA
-676.03
EV to Capital Employed
-1589.07
EV to Sales
16.65
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-42.12%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bearish
Mildly Bearish
RSI
Bullish
No Signal
Bollinger Bands
Bearish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Bearish
Bullish
Dow Theory
Mildly Bearish
Mildly Bearish
OBV
No Trend
No Trend
Shareholding Snapshot : Sep 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 123 Schemes (60.13%)
Foreign Institutions
Held by 367 Foreign Institutions (19.71%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Sep'25 - QoQ
Sep'25
Jun'25
Change(%)
Net Sales
1,249.00
773.70
61.43%
Operating Profit (PBDIT) excl Other Income
381.80
-2.30
16,700.00%
Interest
44.40
40.20
10.45%
Exceptional Items
-103.80
-15.30
-578.43%
Consolidate Net Profit
251.10
-66.30
478.73%
Operating Profit Margin (Excl OI)
294.60%
-20.90%
31.55%
USD in Million.
Net Sales
QoQ Growth in quarter ended Sep 2025 is 61.43% vs 30.21% in Jun 2025
Consolidated Net Profit
QoQ Growth in quarter ended Sep 2025 is 478.73% vs -15.30% in Jun 2025
Annual Results Snapshot (Consolidated) - Dec'24
Dec'24
Dec'23
Change(%)
Net Sales
2,248.20
1,828.30
22.97%
Operating Profit (PBDIT) excl Other Income
-120.20
-228.10
47.30%
Interest
141.90
121.20
17.08%
Exceptional Items
-170.80
-91.00
-87.69%
Consolidate Net Profit
-278.20
-440.20
36.80%
Operating Profit Margin (Excl OI)
-78.70%
-154.30%
7.56%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2024 is 22.97% vs 76.24% in Dec 2023
Consolidated Net Profit
YoY Growth in year ended Dec 2024 is 36.80% vs 61.09% in Dec 2023
About Alnylam Pharmaceuticals, Inc. 
Alnylam Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is engaged in the discovery, development and commercialization of ribonucleic acid (RNA) interference (RNAi) therapeutics. The Company is focused on the use of its N-acetylgalactosamine (GalNAc)-conjugate platform for delivery of small interfering RNAs (siRNAs). Its pipeline of investigational RNAi therapeutics focuses on three Strategic Therapeutic Areas (STArs): Genetic Medicines, with multiple product candidates for the treatment of rare diseases; Cardio-Metabolic Diseases, with product candidates directed toward genetically validated, liver-expressed disease targets for unmet needs in cardiovascular and metabolic diseases, and Hepatic Infectious Diseases, with product candidates designed to address the global health challenges of hepatic infectious diseases, beginning with hepatitis B and hepatitis D viral infections.
Company Coordinates 
Company Details
675 W Kendall St , CAMBRIDGE MA : 02142-1168
Registrar Details






