Compare Alnylam Pharmaceuticals, Inc. with Similar Stocks
Dashboard
1
With a growth in Net Sales of 36.7%, the company declared Very Positive results in Dec 25
- OPERATING CASH FLOW(Y) Highest at USD 524.09 MM
- NET PROFIT(HY) Higher at USD 405.83 MM
- ROCE(HY) Highest at 73.28%
2
With ROE of 45.14%, it has a expensive valuation with a 53.59 Price to Book Value
3
Reducing Promoter Confidence
Stock DNA
Pharmaceuticals & Biotechnology
USD 42,295 Million (Mid Cap)
119.00
NA
0.00%
-0.21
45.14%
53.59
Revenue and Profits:
Net Sales:
1,097 Million
(Quarterly Results - Dec 2025)
Net Profit:
186 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-17.97%
0%
-17.97%
6 Months
-26.89%
0%
-26.89%
1 Year
16.99%
0%
16.99%
2 Years
116.15%
0%
116.15%
3 Years
73.02%
0%
73.02%
4 Years
100.66%
0%
100.66%
5 Years
143.05%
0%
143.05%
Alnylam Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
49.77%
EBIT Growth (5y)
21.11%
EBIT to Interest (avg)
-3.79
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.21
Sales to Capital Employed (avg)
0.91
Tax Ratio
24.11%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
119
Industry P/E
Price to Book Value
53.59
EV to EBIT
84.00
EV to EBITDA
75.61
EV to Capital Employed
67.47
EV to Sales
11.34
PEG Ratio
0.28
Dividend Yield
NA
ROCE (Latest)
80.33%
ROE (Latest)
45.14%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bearish
Mildly Bearish
RSI
No Signal
No Signal
Bollinger Bands
Bearish
Bearish
Moving Averages
Bearish (Daily)
KST
Bearish
Bullish
Dow Theory
Mildly Bearish
No Trend
OBV
No Trend
Mildly Bearish
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 131 Schemes (60.89%)
Foreign Institutions
Held by 409 Foreign Institutions (21.14%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - QoQ
Dec'25
Sep'25
Change(%)
Net Sales
1,097.00
1,249.00
-12.17%
Operating Profit (PBDIT) excl Other Income
145.20
381.80
-61.97%
Interest
129.30
44.40
191.22%
Exceptional Items
135.50
-103.80
230.54%
Consolidate Net Profit
186.40
251.10
-25.77%
Operating Profit Margin (Excl OI)
120.10%
294.60%
-17.45%
USD in Million.
Net Sales
QoQ Growth in quarter ended Dec 2025 is -12.17% vs 61.43% in Sep 2025
Consolidated Net Profit
QoQ Growth in quarter ended Dec 2025 is -25.77% vs 478.73% in Sep 2025
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
3,713.90
2,248.20
65.19%
Operating Profit (PBDIT) excl Other Income
557.20
-120.20
563.56%
Interest
252.60
141.90
78.01%
Exceptional Items
-42.50
-170.80
75.12%
Consolidate Net Profit
313.70
-278.20
212.76%
Operating Profit Margin (Excl OI)
135.10%
-78.70%
21.38%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 65.19% vs 22.97% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 212.76% vs 36.80% in Dec 2024
About Alnylam Pharmaceuticals, Inc. 
Alnylam Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is engaged in the discovery, development and commercialization of ribonucleic acid (RNA) interference (RNAi) therapeutics. The Company is focused on the use of its N-acetylgalactosamine (GalNAc)-conjugate platform for delivery of small interfering RNAs (siRNAs). Its pipeline of investigational RNAi therapeutics focuses on three Strategic Therapeutic Areas (STArs): Genetic Medicines, with multiple product candidates for the treatment of rare diseases; Cardio-Metabolic Diseases, with product candidates directed toward genetically validated, liver-expressed disease targets for unmet needs in cardiovascular and metabolic diseases, and Hepatic Infectious Diseases, with product candidates designed to address the global health challenges of hepatic infectious diseases, beginning with hepatitis B and hepatitis D viral infections.
Company Coordinates 
Company Details
675 W Kendall St , CAMBRIDGE MA : 02142-1168
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