Compare BioCryst Pharmaceuticals, Inc. with Similar Stocks
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With a Negative Book Value, the company has a Weak Long Term Fundamental Strength
- Poor long term growth as Operating profit has grown by an annual rate 21.26% of over the last 5 years
- Company's ability to service its debt is weak with a poor EBIT to Interest (avg) ratio of -2.45
2
With a growth in Net Sales of 209.09%, the company declared Outstanding results in Sep 25
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Risky -
4
Rising Promoter Confidence
Stock DNA
Pharmaceuticals & Biotechnology
USD 2,332 Million (Small Cap)
NA (Loss Making)
NA
0.00%
-1.18
0.71%
-6.01
Revenue and Profits:
Net Sales:
407 Million
(Quarterly Results - Dec 2025)
Net Profit:
246 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
22.08%
0%
22.08%
6 Months
20.98%
0%
20.98%
1 Year
16.77%
0%
16.77%
2 Years
87.62%
0%
87.62%
3 Years
10.59%
0%
10.59%
4 Years
-43.65%
0%
-43.65%
5 Years
-10.73%
0%
-10.73%
BioCryst Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
62.14%
EBIT Growth (5y)
21.26%
EBIT to Interest (avg)
-2.45
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.16
Sales to Capital Employed (avg)
1.20
Tax Ratio
4.47%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
9.23%
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
-6.01
EV to EBIT
36.69
EV to EBITDA
36.07
EV to Capital Employed
38.99
EV to Sales
4.65
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
106.28%
ROE (Latest)
Negative BV
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Bullish
RSI
Bearish
No Signal
Bollinger Bands
Mildly Bullish
Bullish
Moving Averages
Mildly Bearish (Daily)
KST
Bullish
Mildly Bearish
Dow Theory
No Trend
Mildly Bullish
OBV
No Trend
Mildly Bullish
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 65 Schemes (29.15%)
Foreign Institutions
Held by 129 Foreign Institutions (12.75%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - YoY
Dec'25
Dec'24
Change(%)
Net Sales
406.60
131.50
209.20%
Operating Profit (PBDIT) excl Other Income
260.80
-4.20
6,309.52%
Interest
14.10
24.40
-42.21%
Exceptional Items
-10.40
0.00
Consolidate Net Profit
245.80
-26.80
1,017.16%
Operating Profit Margin (Excl OI)
640.50%
-34.30%
67.48%
USD in Million.
Net Sales
YoY Growth in quarter ended Dec 2025 is 209.20% vs 40.79% in Dec 2024
Consolidated Net Profit
YoY Growth in quarter ended Dec 2025 is 1,017.16% vs 56.56% in Dec 2024
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
874.80
450.70
94.10%
Operating Profit (PBDIT) excl Other Income
342.40
-1.30
26,438.46%
Interest
78.90
98.50
-19.90%
Exceptional Items
-17.30
0.00
Consolidate Net Profit
263.90
-88.90
396.85%
Operating Profit Margin (Excl OI)
389.80%
-5.60%
39.54%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 94.10% vs 36.00% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 396.85% vs 60.75% in Dec 2024
About BioCryst Pharmaceuticals, Inc. 
BioCryst Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
BioCryst Pharmaceuticals, Inc. is a biotechnology company. The Company designs, optimizes and develops small molecule drugs that block enzymes involved in the pathogenesis of diseases. The Company focuses on the treatment of rare diseases. It uses X-ray crystallography, computer modeling of molecular structures and chemistry techniques to focus on the three-dimensional molecular structure and active site characteristics of the enzymes that control cellular biology. The Company's drug candidates include RAPIVAB, RAPIACTA, ALPIVAB, PERAMIFLU, Avoralstat, BCX7353, other second generation hereditary angioedema (HAE) compounds, Galidesivir and Forodesine. Its product RAPIVAB contains peramivir. ALPIVAB is an intravenous neuraminidase inhibitor. Galidesivir is a broad-spectrum antiviral (BSAV) research program developed for the treatment of hemorrhagic fever viruses. Forodesine is a Purine Nucleoside Phosphorylase (PNP) inhibitor in development by Mundipharma as a treatment for cancer.
Company Coordinates 
Company Details
4505 Emperor Blvd Ste 200 , DURHAM NC : 27703-8457
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