CRISPR Therapeutics AG

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: CH0334081137
USD
58.18
6.6 (12.8%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

900.02 k

Shareholding (Mar 2025)

FII

22.03%

Held by 161 FIIs

DII

48.2%

Held by 34 DIIs

Promoter

3.85%

How big is CRISPR Therapeutics AG?

22-Jun-2025

As of Jun 18, CRISPR Therapeutics AG has a market capitalization of 3,737.84 million, with net sales of 37.67 million and a net profit of -385.66 million over the latest four quarters. The company reported shareholder's funds of 1,932.08 million and total assets of 2,242.03 million as of Dec 24.

Market Cap: <BR>As of Jun 18, CRISPR Therapeutics AG has a market capitalization of 3,737.84 million, categorizing it as a Mid Cap company.<BR><BR>Recent Quarterly Performance: <BR>For the latest four quarters, CRISPR Therapeutics AG reported net sales of 37.67 million and a net profit of -385.66 million.<BR><BR>Balance Sheet Snapshot: <BR>As of Dec 24, the company reported shareholder's funds of 1,932.08 million and total assets of 2,242.03 million.

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What does CRISPR Therapeutics AG do?

22-Jun-2025

CRISPR Therapeutics AG is a Switzerland-based gene-editing company focused on developing gene-based medicines for serious diseases. As of March 2025, it reported net sales of $1 million and a net loss of $136 million, with a market cap of approximately $3.74 billion.

Overview:<BR>CRISPR Therapeutics AG is a Switzerland-based gene-editing company in the Pharmaceuticals & Biotechnology industry, focused on developing transformative gene-based medicines for serious diseases.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 1 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -136 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 3,737.84 Million (Mid Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.01 <BR>Return on Equity: -21.08% <BR>Price to Book: 2.04<BR><BR>Contact Details:<BR>Address: Baarerstrasse 14, ZUG ZUG: 6300 <BR>Tel: ['41 41 5613277'] <BR>Website: http://www.crisprtx.com/about-us/contact

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Should I buy, sell or hold CRISPR Therapeutics AG?

22-Jun-2025

Who are in the management team of CRISPR Therapeutics AG?

22-Jun-2025

As of March 2022, the management team of CRISPR Therapeutics AG includes Dr. Rodger Novak (Chairman, President, Co-Founder) and Dr. Samarth Kulkarni (CEO, Director), along with independent directors Dr. Ali Behbahani, Dr. Bradley Bolzon, Dr. Simeon George, Mr. John Greene, and Dr. Katherine High.

As of March 2022, the management team of CRISPR Therapeutics AG includes the following individuals:<BR><BR>- Dr. Rodger Novak, who serves as the Chairman of the Board, President, and Co-Founder.<BR>- Dr. Samarth Kulkarni, who is the Chief Executive Officer and a Director.<BR><BR>Additionally, the Board of Directors includes several independent directors: Dr. Ali Behbahani, Dr. Bradley Bolzon, Dr. Simeon George, Mr. John Greene, and Dr. Katherine High.

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Is CRISPR Therapeutics AG overvalued or undervalued?

20-Sep-2025

As of August 8, 2022, CRISPR Therapeutics AG is considered overvalued with a risky valuation grade, highlighted by a negative P/E ratio of -13.27 and a negative ROE of -21.08%, despite a strong year-to-date stock return of 59.91%.

As of 8 August 2022, the valuation grade for CRISPR Therapeutics AG moved from fair to risky, indicating a shift towards a more negative outlook. The company is currently considered overvalued given its financial metrics, particularly with a Price to Book Value of 1.98 and a negative EV to EBIT of -3.76. Additionally, the Return on Equity (ROE) stands at -21.08%, further highlighting the challenges the company faces in generating returns for its shareholders.<BR><BR>In comparison to its peers, CRISPR Therapeutics AG's P/E ratio is notably negative at -13.27, while Illumina, Inc. and BioMarin Pharmaceutical, Inc. have fair valuations with P/E ratios of 19.09 and 15.17, respectively. This stark contrast underscores the difficulties CRISPR is experiencing relative to its industry. Despite a strong year-to-date stock return of 59.91%, which outperformed the S&P 500's 12.22%, the longer-term outlook remains concerning, as reflected in the negative returns over the 3-year and 5-year periods.

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Is CRISPR Therapeutics AG technically bullish or bearish?

05-Nov-2025

As of October 31, 2025, CRISPR Therapeutics AG shows a bullish technical trend, supported by positive MACD indicators and a strong year-to-date return of 43.32%, despite recent underperformance compared to the S&P 500 and mixed signals from other indicators.

As of 31 October 2025, the technical trend for CRISPR Therapeutics AG has changed from mildly bullish to bullish. The weekly and monthly MACD indicators are both bullish, supporting a positive outlook. While the Bollinger Bands indicate a mildly bullish stance on both weekly and monthly time frames, the daily moving averages show a mildly bullish trend. However, the KST and Dow Theory present a mixed picture, with weekly signals being mildly bearish and monthly signals bullish. <BR><BR>The stock has underperformed the S&P 500 over the past week and month, with returns of -14.17% and -16.73% compared to the S&P 500's gains of 0.71% and 1.92%, respectively. Despite this recent underperformance, the year-to-date return of 43.32% significantly outpaces the S&P 500's 16.30%. Overall, the current technical stance is bullish, albeit with some caution due to mixed indicators.

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iScoreScore
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Dashboard
1

Poor Management Efficiency with a low ROE of 3.15%

  • The company has been able to generate a Return on Equity (avg) of 3.15% signifying low profitability per unit of shareholders funds
2

The company has declared Negative results for the last 4 consecutive quarters

3

Risky - Negative EBITDA

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 4,930 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-1.00

stock-summary
Return on Equity

-21.71%

stock-summary
Price to Book

2.88

Revenue and Profits:
Net Sales:
1 Million
(Quarterly Results - Jun 2025)
Net Profit:
-209 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
9.82%
0%
9.82%
6 Months
52.94%
0%
52.94%
1 Year
13.54%
0%
13.54%
2 Years
-15.25%
0%
-15.25%
3 Years
6.75%
0%
6.75%
4 Years
-16.99%
0%
-16.99%
5 Years
-58.58%
0%
-58.58%

CRISPR Therapeutics AG for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
-33.34%
EBIT Growth (5y)
-355.30%
EBIT to Interest (avg)
-271.84
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.01
Sales to Capital Employed (avg)
0.08
Tax Ratio
1.04%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
86.49%
ROCE (avg)
229.94%
ROE (avg)
3.15%
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
1.98
EV to EBIT
-3.76
EV to EBITDA
-3.91
EV to Capital Employed
-146.84
EV to Sales
47.28
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-21.08%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bearish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Mildly Bullish
Dow Theory
No Trend
Mildly Bearish
OBV
No Trend
Mildly Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 53 Schemes (25.91%)

Foreign Institutions

Held by 161 Foreign Institutions (22.03%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
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        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 0.00% vs -97.48% in Mar 2025",
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        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -53.31% vs -264.61% in Mar 2025",
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      "header": [
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        "Mar'25",
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          "val1": "0.90",
          "val2": "0.90",
          "chgp": "",
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          "field": "Operating Profit (PBDIT) excl Other Income",
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          "chgp": "10.58%",
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          "chgp_class": "neutral"
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          "field": "Consolidate Net Profit",
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          "val2": "-136.00",
          "chgp": "-53.31%",
          "chgp_class": "negative"
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          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-149,182.70%",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
0.90
0.90
Operating Profit (PBDIT) excl Other Income
-128.50
-143.70
10.58%
Interest
0.00
0.00
Exceptional Items
-96.30
0.00
Consolidate Net Profit
-208.50
-136.00
-53.31%
Operating Profit Margin (Excl OI)
-149,182.70%
-171,588.40%
2,240.57%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 0.00% vs -97.48% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -53.31% vs -264.61% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
37.30
371.20
-89.95%
Operating Profit (PBDIT) excl Other Income
-447.30
-202.70
-120.67%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-366.30
-153.60
-138.48%
Operating Profit Margin (Excl OI)
-12,503.80%
-599.50%
-1,190.43%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is -89.95% vs 30,833.33% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is -138.48% vs 76.38% in Dec 2023

stock-summaryCompany CV
About CRISPR Therapeutics AG stock-summary
stock-summary
CRISPR Therapeutics AG
Pharmaceuticals & Biotechnology
CRISPR Therapeutics AG is a Switzerland-based gene-editing company. It focuses on the development of transformative gene-based medicines for serious diseases. The Company develops its products using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 gene-editing platform, which allows for precise directed changes to genomic deoxyribonucleic acid (DNA). The Company has a portfolio of therapeutic programs in a range of disease areas, including hemoglobinopathies, oncology, regenerative medicine and rare diseases. Its lead product candidate is CTX001, an ex vivo CRISPR gene-edited therapy for treating patients suffering from transfusion-dependent beta thalassemia or severe sickle cell disease in which a patient’s hematopoietic stem cells are engineered to produce high levels of fetal hemoglobin in red blood cells. The Company has business operations in London and the United Kingdom, as well as research and development operations in the United States.
Company Coordinates stock-summary
Company Details
Baarerstrasse 14 , ZUG ZUG : 6300
Registrar Details