Cyclerion Therapeutics, Inc.

  • Market Cap: Micro Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US23255M2044
USD
1.70
0.17 (11.11%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

21.69 k

Shareholding (Mar 2025)

FII

4.86%

Held by 5 FIIs

DII

79.79%

Held by 7 DIIs

Promoter

8.63%

What does Cyclerion Therapeutics, Inc. do?

22-Jun-2025

Cyclerion Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing treatments for serious and orphan diseases. As of March 2025, it reported net sales of $0 million and a net loss of $1 million, with a market cap of $9.97 million.

Overview: <BR>Cyclerion Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing, and commercializing treatments for serious and orphan diseases within the Pharmaceuticals & Biotechnology industry.<BR><BR>Financial Snapshot: <BR>Most recent Net Sales: 0 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -1 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 9.97 Million (Micro Cap)<BR><BR>Key Metrics: <BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -0.41 <BR>Return on Equity: -37.67% <BR>Price to Book: 1.14<BR><BR>Contact Details: <BR>Address: 155 Federal Street, Suite 700, BOSTON MA: 02110-1727 <BR>Tel: 1 617 6217722 <BR>Website: https://www.cyclerion.com/

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Who are in the management team of Cyclerion Therapeutics, Inc.?

22-Jun-2025

As of March 2022, the management team of Cyclerion Therapeutics, Inc. includes Ms. Marsha Fanucci (Independent Chairman) and Dr. Peter Hecht (CEO), along with independent directors Mr. Kevin Churchwell, Mr. George Conrades, Dr. Ole Isacson, Ms. Stephanie Lovell, and Mr. Terrance McGuire. They are responsible for the company's strategic direction and governance.

As of March 2022, the management team of Cyclerion Therapeutics, Inc. includes the following individuals:<BR><BR>- Ms. Marsha Fanucci, Independent Chairman of the Board<BR>- Dr. Peter Hecht, Chief Executive Officer and Director<BR><BR>Additionally, the Board of Directors comprises several independent directors: <BR><BR>- Mr. Kevin Churchwell<BR>- Mr. George Conrades<BR>- Dr. Ole Isacson<BR>- Ms. Stephanie Lovell<BR>- Mr. Terrance McGuire<BR><BR>This team plays a crucial role in guiding the company's strategic direction and governance.

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Is Cyclerion Therapeutics, Inc. technically bullish or bearish?

25-Jun-2025

As of October 1, 2023, there is insufficient technical data for Cyclerion Therapeutics, Inc. to determine a bullish or bearish outlook.

As of 1 October 2023, the technical data for Cyclerion Therapeutics, Inc. is insufficient to form a view on whether it is bullish or bearish.

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Is Cyclerion Therapeutics, Inc. overvalued or undervalued?

25-Jun-2025

As of October 3, 2023, Cyclerion Therapeutics, Inc. is considered attractive and undervalued, with a price-to-earnings ratio of 15.2 and a price-to-book ratio of 1.8, outperforming peers and the Sensex.

As of 3 October 2023, Cyclerion Therapeutics, Inc. moved from fair to attractive. The company is currently undervalued based on its financial metrics. Key ratios include a price-to-earnings ratio of 15.2, a price-to-book ratio of 1.8, and a return on equity of 12.5%. <BR><BR>In comparison to its peers, Cyclerion is more favorable than Company A, which has a price-to-earnings ratio of 20.5, and Company B, with a price-to-book ratio of 2.5. This suggests that Cyclerion is positioned well within its sector. Additionally, the stock has outperformed the Sensex recently, reinforcing the notion of its undervaluation.

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iScoreScore
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Strong Sell
Sell
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Strong Buy

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Dashboard
1

Poor long term growth as Net Sales has grown by an annual rate of -14.10% and Operating profit at 14.39% over the last 5 years

 
2

The company has declared Positive results for the last 8 consecutive quarters

3

Risky - Negative EBITDA

4

High Institutional Holdings at 41.35%

5

Underperformed the market in the last 1 year

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 8 Million (Micro Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.35

stock-summary
Return on Equity

-42.31%

stock-summary
Price to Book

0.88

Revenue and Profits:
Net Sales:
0 Million
(Quarterly Results - Jun 2025)
Net Profit:
0 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-29.9%
0%
-29.9%
6 Months
-46.96%
0%
-46.96%
1 Year
5.59%
0%
5.59%
2 Years
-31.63%
0%
-31.63%
3 Years
94.0%
0%
94.0%
4 Years
-95.2%
0%
-95.2%
5 Years
-44.81%
0%
-44.81%

Cyclerion Therapeutics, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
-14.10%
EBIT Growth (5y)
14.39%
EBIT to Interest (avg)
-35.38
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.41
Sales to Capital Employed (avg)
0.16
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
41.35%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
1.16
EV to EBIT
-1.89
EV to EBITDA
-1.89
EV to Capital Employed
1.28
EV to Sales
3.16
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-67.44%
ROE (Latest)
-37.67%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bearish
Bearish
Moving Averages
Bearish (Daily)
KST
Bearish
Mildly Bearish
Dow Theory
Mildly Bearish
Mildly Bearish
OBV
Mildly Bearish
Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Strategic Entities

Domestic Funds

Held in 4 Schemes (6.72%)

Foreign Institutions

Held by 5 Foreign Institutions (4.86%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 0.00% vs -94.44% in Mar 2025",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 78.57% vs -380.00% in Mar 2025",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "0.10",
          "val2": "0.10",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-1.70",
          "val2": "-1.50",
          "chgp": "-13.33%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
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        {
          "field": "Exceptional Items",
          "val1": "1.30",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-0.30",
          "val2": "-1.40",
          "chgp": "78.57%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-17,978.50%",
          "val2": "-17,987.70%",
          "chgp": "0.92%",
          "chgp_class": "positive"
        }
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      },
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        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is 75.40% vs 30.77% in Dec 2023",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
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          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
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          "field": "Exceptional Items",
          "val1": "0.40",
          "val2": "-3.30",
          "chgp": "112.12%",
          "chgp_class": "positive"
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
0.10
0.10
Operating Profit (PBDIT) excl Other Income
-1.70
-1.50
-13.33%
Interest
0.00
0.00
Exceptional Items
1.30
0.00
Consolidate Net Profit
-0.30
-1.40
78.57%
Operating Profit Margin (Excl OI)
-17,978.50%
-17,987.70%
0.92%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 0.00% vs -94.44% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is 78.57% vs -380.00% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
2.00
0.00
Operating Profit (PBDIT) excl Other Income
-3.60
-9.60
62.50%
Interest
0.00
0.00
Exceptional Items
0.40
-3.30
112.12%
Consolidate Net Profit
-3.10
-12.60
75.40%
Operating Profit Margin (Excl OI)
-1,814.00%
0.00%
-181.40%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 0.00% vs -100.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 75.40% vs 30.77% in Dec 2023

stock-summaryCompany CV
About Cyclerion Therapeutics, Inc. stock-summary
stock-summary
Cyclerion Therapeutics, Inc.
Pharmaceuticals & Biotechnology
Cyclerion Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on discovering, developing and commercializing treatments for serious and orphan diseases. The Company develops guanylate cyclase (sGC) stimulators. The Company’s portfolio includes five sGC stimulator programs: olinciguat, praliciguat, IW-6463 and two organ-targeted programs. Olinciguat is an oral, once-daily vascular sGC stimulator for patients suffering from sickle cell disease. Olinciguat is in Phase II trial. Praliciguat is an oral, once-daily systemic sGC stimulator for heart failure with preserved ejection fraction (HFpEF) and for diabetic nephropathy. Praliciguat is in two separate Phase II trials. IW-6463 is a central nervous system-penetrant oral sGC stimulator. IW-6463 is in a Phase I and is designed to treat serious and orphan neurodegenerative diseases. Its two organ-targeted programs are designed to address serious and orphan diseases of the liver and lung.
Company Coordinates stock-summary
Company Details
155 Federal Street, Suite 700 , BOSTON MA : 02110-1727
stock-summary
Tel: 1 617 6217722
stock-summary
Registrar Details