OPKO Health, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US68375N1037
USD
1.35
0.02 (1.5%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

1.28 M

Shareholding (Mar 2025)

FII

4.25%

Held by 101 FIIs

DII

83.67%

Held by 37 DIIs

Promoter

1.01%

How big is OPKO Health, Inc.?

22-Jun-2025

As of Jun 18, OPKO Health, Inc. has a market capitalization of 1,061.48 million and reported net sales of 689.37 million with a net profit of -39.02 million over the latest four quarters. Shareholder's funds are 1,365.45 million, and total assets amount to 2,200.21 million.

As of Jun 18, OPKO Health, Inc. has a market capitalization of 1,061.48 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the sum of net sales for the latest four quarters is 689.37 million, while the sum of net profit for the same period is -39.02 million.<BR><BR>As of Dec 24, the shareholder's funds are reported at 1,365.45 million, and total assets amount to 2,200.21 million.

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What does OPKO Health, Inc. do?

22-Jun-2025

OPKO Health, Inc. is a micro-cap healthcare company in the Pharmaceuticals & Biotechnology sector, reporting net sales of $150 million and a net loss of $68 million as of March 2025. The company has a market cap of approximately $1.06 billion and does not pay dividends.

Overview:<BR>OPKO Health, Inc. is a healthcare company operating in the Pharmaceuticals & Biotechnology industry, categorized as a micro-cap company.<BR><BR>Financial Snapshot:<BR>- Net Sales: 150 Million (Quarterly Results - Mar 2025)<BR>- Net Profit: -68 Million (Quarterly Results - Mar 2025)<BR>- Market cap: USD 1,061.48 Million (Micro Cap)<BR><BR>Key Metrics:<BR>- P/E: NA (Loss Making)<BR>- Industry P/E: NA<BR>- Dividend Yield: 0.00%<BR>- Debt Equity: 0.01<BR>- Return on Equity: -3.42%<BR>- Price to Book: 0.81<BR><BR>Contact Details:<BR>- Address: 4400 Biscayne Blvd, MIAMI FL: 33137<BR>- Tel: ['1 305 5754181', '1 310 6917100']<BR>- Website: http://www.opko.com

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Should I buy, sell or hold OPKO Health, Inc.?

22-Jun-2025

Who are in the management team of OPKO Health, Inc.?

22-Jun-2025

As of March 2022, the management team of OPKO Health, Inc. includes Dr. Phillip Frost (Chairman and CEO), Dr. Jane Hsiao (Vice Chairman and CTO), Dr. Jon Cohen (Executive Chairman of BioReference Laboratories), and Mr. Steven Rubin (Executive VP - Administration), along with several Independent Directors. This team offers a diverse range of expertise to the company.

As of March 2022, the management team of OPKO Health, Inc. includes:<BR><BR>- Dr. Phillip Frost, who serves as the Chairman of the Board and Chief Executive Officer.<BR>- Dr. Jane Hsiao, who is the Vice Chairman of the Board and Chief Technical Officer.<BR>- Dr. Jon Cohen, who is the Director and Executive Chairman of BioReference Laboratories.<BR>- Mr. Steven Rubin, who holds the position of Executive Vice President - Administration and Director.<BR>- Dr. Robert Fishel, Dr. Anthony Japour, Dr. Richard Krasno, Dr. Richard Lerner, and Dr. Roger Medel, all of whom are Independent Directors. <BR><BR>This team brings a diverse range of expertise to the company.

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Is OPKO Health, Inc. overvalued or undervalued?

20-Sep-2025

As of February 24, 2022, OPKO Health, Inc. is considered a risky investment due to its overvaluation indicated by a Price to Book Value of 0.85, a negative EV to EBITDA ratio of -6.52, and poor stock performance with a 1-year return of -6.79% compared to the S&P 500's 17.14%.

As of 24 February 2022, the valuation grade for OPKO Health, Inc. has moved from attractive to risky, indicating a deterioration in its investment appeal. The company appears to be overvalued based on its current financial metrics, particularly with a Price to Book Value of 0.85 and an EV to Sales ratio of 1.64. Additionally, the EV to EBITDA ratio stands at -6.52, reflecting significant operational challenges.<BR><BR>In comparison to its peers, OPKO Health, Inc. has a notably negative EV to EBITDA ratio of -7.2480, while Hims & Hers Health, Inc. is considered expensive with a P/E ratio of 54.7633, and RadNet, Inc. shows a risky valuation with a P/E of 123.7949. The company's recent stock performance has been lackluster, with a 1-year return of -6.79% compared to the S&P 500's 17.14%, further reinforcing the notion that OPKO Health, Inc. is overvalued in the current market environment.

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Is OPKO Health, Inc. technically bullish or bearish?

07-Oct-2025

As of October 3, 2025, OPKO Health, Inc. shows a mildly bullish trend supported by positive MACD and Bollinger Bands, although daily moving averages are mildly bearish, and while it has outperformed the S&P 500 recently, it has underperformed over the longer term.

As of 3 October 2025, the technical trend for OPKO Health, Inc. has changed from sideways to mildly bullish. The weekly MACD is bullish, and the monthly MACD is mildly bullish, supporting the positive outlook. Bollinger Bands are bullish on both weekly and monthly time frames. The Dow Theory also indicates a mildly bullish stance on both weekly and monthly charts. However, the daily moving averages are mildly bearish, which adds some caution to the overall bullish sentiment.<BR><BR>In terms of returns, OPKO Health has outperformed the S&P 500 over the past week and month, with returns of 7.48% and 17.04% respectively, compared to the S&P 500's 1.09% and 4.15%. However, the longer-term performance shows significant underperformance over the 3-year and 5-year periods. Overall, the current technical stance is mildly bullish, driven by the positive indicators despite some mixed signals in the moving averages.

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iScoreScore
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Strong Sell
Sell
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Strong Buy

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Dashboard
1

Poor Management Efficiency with a low ROCE of 1.42%

  • The company has been able to generate a Return on Capital Employed (avg) of 1.42% signifying low profitability per unit of total capital (equity and debt)
2

Poor long term growth as Net Sales has grown by an annual rate of -7.22% over the last 5 years

3

Risky -

4

Consistent Underperformance against the benchmark over the last 3 years

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 1,169 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

0.06

stock-summary
Return on Equity

-14.14%

stock-summary
Price to Book

0.90

Revenue and Profits:
Net Sales:
157 Million
(Quarterly Results - Jun 2025)
Net Profit:
-148 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-2.17%
0%
-2.17%
6 Months
-2.17%
0%
-2.17%
1 Year
-14.56%
0%
-14.56%
2 Years
-11.76%
0%
-11.76%
3 Years
-8.16%
0%
-8.16%
4 Years
-65.03%
0%
-65.03%
5 Years
-70.78%
0%
-70.78%

OPKO Health, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
-7.22%
EBIT Growth (5y)
-200.15%
EBIT to Interest (avg)
-6.73
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
0.01
Sales to Capital Employed (avg)
0.45
Tax Ratio
100.00%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
38.64%
ROCE (avg)
1.42%
ROE (avg)
1.40%
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
0.85
EV to EBIT
-4.20
EV to EBITDA
-6.52
EV to Capital Employed
0.85
EV to Sales
1.64
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-20.34%
ROE (Latest)
-3.42%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bearish
Bearish
Moving Averages
Bearish (Daily)
KST
Mildly Bearish
Mildly Bearish
Dow Theory
Mildly Bearish
Mildly Bullish
OBV
Mildly Bearish
Mildly Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 41 Schemes (11.07%)

Foreign Institutions

Held by 101 Foreign Institutions (4.25%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 4.53% vs -18.30% in Mar 2025",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -119.53% vs -582.86% in Mar 2025",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "156.80",
          "val2": "150.00",
          "chgp": "4.53%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-37.00",
          "val2": "-43.70",
          "chgp": "15.33%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "70.30",
          "val2": "15.50",
          "chgp": "353.55%",
          "chgp_class": "negative"
        },
        {
          "field": "Exceptional Items",
          "val1": "0.30",
          "val2": "-2.00",
          "chgp": "115.00%",
          "chgp_class": "positive"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-148.40",
          "val2": "-67.60",
          "chgp": "-119.53%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-382.50%",
          "val2": "-447.90%",
          "chgp": "6.54%",
          "chgp_class": "positive"
        }
      ]
    }
  },
  {
    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'24",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in year ended Dec 2024 is -17.42% vs -14.01% in Dec 2023",
        "dir": -1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is 71.84% vs 42.48% in Dec 2023",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "713.10",
          "val2": "863.50",
          "chgp": "-17.42%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-175.40",
          "val2": "-52.80",
          "chgp": "-232.20%",
          "chgp_class": "negative"
        },
        {
          "field": "Interest",
          "val1": "47.50",
          "val2": "13.50",
          "chgp": "251.85%",
          "chgp_class": "negative"
        },
        {
          "field": "Exceptional Items",
          "val1": "-6.30",
          "val2": "-0.30",
          "chgp": "-2,000.00%",
          "chgp_class": "negative"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-53.20",
          "val2": "-188.90",
          "chgp": "71.84%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-383.60%",
          "val2": "-183.00%",
          "chgp": "-20.06%",
          "chgp_class": "negative"
        }
      ]
    }
  }
]
Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
156.80
150.00
4.53%
Operating Profit (PBDIT) excl Other Income
-37.00
-43.70
15.33%
Interest
70.30
15.50
353.55%
Exceptional Items
0.30
-2.00
115.00%
Consolidate Net Profit
-148.40
-67.60
-119.53%
Operating Profit Margin (Excl OI)
-382.50%
-447.90%
6.54%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 4.53% vs -18.30% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -119.53% vs -582.86% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
713.10
863.50
-17.42%
Operating Profit (PBDIT) excl Other Income
-175.40
-52.80
-232.20%
Interest
47.50
13.50
251.85%
Exceptional Items
-6.30
-0.30
-2,000.00%
Consolidate Net Profit
-53.20
-188.90
71.84%
Operating Profit Margin (Excl OI)
-383.60%
-183.00%
-20.06%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is -17.42% vs -14.01% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 71.84% vs 42.48% in Dec 2023

stock-summaryCompany CV
About OPKO Health, Inc. stock-summary
stock-summary
OPKO Health, Inc.
Pharmaceuticals & Biotechnology
OPKO Health, Inc. is a healthcare company. Its segments include Pharmaceutical, Diagnostics and Corporate. Pharmaceutical consists of the pharmaceutical operations in Chile, Mexico, Ireland, Israel and Spain and its pharmaceutical research and development operations. Diagnostics consists of the clinical laboratory operations in Bio-Reference Laboratories (Bio-Reference) and its point-of-care operations. Through Bio-Reference, it operates laboratory divisions, such as Bio-Reference, GenPath (Oncology), GenPath (Women's Health), GeneDx and Laboratorio Bueno Salud. As of December 31, 2016, it had one commercial stage pharmaceutical product and several pharmaceutical compounds and technologies in various stages of research and development for a range of indications and conditions, including Renal Products, Biologics, hGH-CTP, Factor VII, Oxyntomodulin, active pharmaceutical ingredients, Oligonucleotide Therapeutics, NK-1 Program, Asthma and chronic obstructive pulmonary disease.
Company Coordinates stock-summary
Company Details
4400 Biscayne Blvd , MIAMI FL : 33137
stock-summary
Tel: 1 305 57541811 310 6917100
stock-summary
Registrar Details