Praxis Precision Medicines, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US74006W2070
USD
189.97
10.85 (6.06%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

253.29 k

Shareholding (Mar 2025)

FII

13.12%

Held by 75 FIIs

DII

50.32%

Held by 26 DIIs

Promoter

13.22%

How big is Praxis Precision Medicines, Inc.?

22-Jun-2025

As of Jun 18, Praxis Precision Medicines, Inc. has a market capitalization of 885.24 million and reported net sales of 8.12 million with a net profit of -212.57 million over the latest four quarters. Shareholder's funds are 445.45 million and total assets are 483.11 million as of Dec 24.

As of Jun 18, Praxis Precision Medicines, Inc. has a market capitalization of 885.24 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the sum of net sales for the latest four quarters is 8.12 million, while the sum of net profit for the same period is -212.57 million.<BR><BR>As of Dec 24, the reporting period shows shareholder's funds of 445.45 million and total assets of 483.11 million.

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What does Praxis Precision Medicines, Inc. do?

22-Jun-2025

Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company focused on developing therapies for central nervous system disorders. It has a market cap of $885.24 million and reported a net profit loss of $69 million as of March 2025.

Overview:<BR>Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company engaged in developing therapies for central nervous system disorders characterized by neuronal imbalance, operating within the Pharmaceuticals & Biotechnology industry and classified as a micro-cap company.<BR><BR>Financial Snapshot:<BR>- Most recent Net Profit: -69 Million (Quarterly Results - Mar 2025)<BR>- Market-cap: USD 885.24 Million (Micro Cap)<BR><BR>Key Metrics:<BR>- P/E: NA (Loss Making)<BR>- Industry P/E: NA<BR>- Dividend Yield: 0.00%<BR>- Debt Equity: -0.74<BR>- Return on Equity: -48.40%<BR>- Price to Book: 2.02<BR><BR>Contact Details:<BR>- Address: 101 Main Street, #1210, Suite 1210, CAMBRIDGE MA: 02142<BR>- Tel: 1 617 9492220<BR>- Website: https://praxismedicines.com/

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Should I buy, sell or hold Praxis Precision Medicines, Inc.?

22-Jun-2025

Who are in the management team of Praxis Precision Medicines, Inc.?

22-Jun-2025

As of March 2022, the management team of Praxis Precision Medicines, Inc. includes Mr. Kiran Reddy, who is the Co-Founder and Director of the company.

As of March 2022, the management team of Praxis Precision Medicines, Inc. includes Mr. Kiran Reddy, who serves as the Co-Founder and Director of the company.

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Is Praxis Precision Medicines, Inc. overvalued or undervalued?

20-Sep-2025

As of August 9, 2023, Praxis Precision Medicines, Inc. is considered risky and overvalued due to significant losses and poor financial metrics, underperforming the S&P 500 with a return of -23.83% compared to the index's 17.14%.

As of 9 August 2023, the valuation grade for Praxis Precision Medicines, Inc. has moved from does not qualify to risky, indicating increased uncertainty regarding its financial health. The company appears to be overvalued given its significant losses and poor financial metrics, including a Price to Book Value of 2.07, an EV to Sales ratio of 71.50, and a ROE of -48.40%. <BR><BR>In comparison to its peers, Ocular Therapeutix, Inc. has a more severe P/E ratio of -9.92 and an EV to EBITDA of -8.44, suggesting that both companies are struggling, but Praxis's ratios indicate a relatively less favorable position. Notably, over the past year, Praxis has underperformed against the S&P 500, with a return of -23.83% compared to the index's 17.14%, reinforcing the perception of overvaluation.

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Is Praxis Precision Medicines, Inc. technically bullish or bearish?

28-Oct-2025

As of October 24, 2025, Praxis Precision Medicines, Inc. has a mildly bullish technical trend, supported by bullish moving averages and Bollinger Bands, despite bearish RSI readings and long-term underperformance compared to the S&P 500.

As of 24 October 2025, the technical trend for Praxis Precision Medicines, Inc. has changed from bullish to mildly bullish. The weekly MACD indicates a bullish stance, while the monthly MACD is mildly bullish. However, the RSI readings are bearish for both weekly and monthly periods. The Bollinger Bands show a mildly bullish trend weekly and bullish monthly. Daily moving averages are bullish, but the KST is bullish weekly and mildly bearish monthly. Dow Theory indicates no trend weekly and mildly bullish monthly, while the OBV is bullish monthly but shows no trend weekly.<BR><BR>In terms of performance, the stock has returned 255.26% over the past month, significantly outperforming the S&P 500's 2.32% return, but it has underperformed over the longer term, with a 5-year return of -62.58% compared to the S&P 500's 95.99%. Overall, the current technical stance is mildly bullish, driven primarily by the moving averages and Bollinger Bands.

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Strong Sell
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Strong Buy

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Dashboard
1

Negative results in Jun 25

  • OPERATING CASH FLOW(Y) Lowest at USD -191.24 MM
  • OPERATING PROFIT(Q) Lowest at USD -76.02 MM
  • PRE-TAX PROFIT(Q) Lowest at USD -71.13 MM
2

Risky - Negative EBITDA

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 858 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.74

stock-summary
Return on Equity

-62.10%

stock-summary
Price to Book

2.12

Revenue and Profits:
Net Sales:
(Quarterly Results - Jun 2025)
Net Profit:
-71 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
308.1%
0%
308.1%
6 Months
361.09%
0%
361.09%
1 Year
163.44%
0%
163.44%
2 Years
981.83%
0%
981.83%
3 Years
8574.43%
0%
8574.43%
4 Years
-29.64%
0%
-29.64%
5 Years
-69.82%
0%
-69.82%

Praxis Precision Medicines, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
54.38%
EBIT Growth (5y)
-238.58%
EBIT to Interest (avg)
-167.42
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.74
Sales to Capital Employed (avg)
0.02
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
2.07
EV to EBIT
-2.49
EV to EBITDA
-2.50
EV to Capital Employed
5.17
EV to Sales
71.50
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-207.51%
ROE (Latest)
-48.40%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Bullish
RSI
No Signal
Bearish
Bollinger Bands
Bullish
Mildly Bullish
Moving Averages
Bullish (Daily)
KST
Bullish
Mildly Bearish
Dow Theory
No Trend
No Trend
OBV
Mildly Bullish
No Trend
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 45 Schemes (23.34%)

Foreign Institutions

Held by 75 Foreign Institutions (13.12%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
0.00
0.00
Operating Profit (PBDIT) excl Other Income
-76.00
-74.70
-1.74%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-71.10
-69.30
-2.60%
Operating Profit Margin (Excl OI)
0.00%
0.00%
NA
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 0.00% vs -100.00% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -2.60% vs -18.06% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
8.60
2.40
258.33%
Operating Profit (PBDIT) excl Other Income
-199.80
-125.90
-58.70%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-182.80
-123.30
-48.26%
Operating Profit Margin (Excl OI)
-23,402.90%
-51,644.10%
2,824.12%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 258.33% vs 0.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is -48.26% vs 42.38% in Dec 2023

stock-summaryCompany CV
About Praxis Precision Medicines, Inc. stock-summary
stock-summary
Praxis Precision Medicines, Inc.
Pharmaceuticals & Biotechnology
Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in translating genetic insights into the development of therapies for central nervous system (CNS) disorders characterized by neuronal imbalance. Its development stage products include PRAX-114, PRAX-944 and PRAX-562. PRAX-114 is an extrasynaptic-preferring gamma-aminobutyric acid-A (GABAA) receptor positive allosteric modulator (PAM) for the treatment of patients suffering from major depressive disorder (MDD) and perimenopausal depression (PMD). PRAX-944 is a differentiated selective small molecule inhibitor of T-type calcium channel, for the treatment of essential tremor (ET). PRAX-562 is the selective, persistent sodium current blocker in development for the treatment of a range of CNS disorders.
Company Coordinates stock-summary
Company Details
101 Main Street, #1210, Suite 1210 , CAMBRIDGE MA : 02142
Registrar Details