Compare Praxis Precision Medicines, Inc. with Similar Stocks
Stock DNA
Pharmaceuticals & Biotechnology
USD 8,495 Million (Small Cap)
NA (Loss Making)
NA
0.00%
-0.68
-34.54%
9.67
Revenue and Profits:
Net Sales:
(Quarterly Results - Dec 2025)
Net Profit:
-89 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
6.67%
0%
6.67%
6 Months
505.16%
0%
505.16%
1 Year
692.32%
0%
692.32%
2 Years
445.96%
0%
445.96%
3 Years
34347.18%
0%
34347.18%
4 Years
74.91%
0%
74.91%
5 Years
-41.33%
0%
-41.33%
Praxis Precision Medicines, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
0
EBIT Growth (5y)
-226.69%
EBIT to Interest (avg)
-167.42
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.74
Sales to Capital Employed (avg)
0.02
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
9.67
EV to EBIT
-24.20
EV to EBITDA
-24.21
EV to Capital Employed
28.31
EV to Sales
NA
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-116.95%
ROE (Latest)
-34.54%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
Bearish
Bollinger Bands
Mildly Bullish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
No Trend
Mildly Bullish
OBV
No Trend
No Trend
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 58 Schemes (38.02%)
Foreign Institutions
Held by 103 Foreign Institutions (22.94%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - QoQ
Dec'25
Sep'25
Change(%)
Net Sales
0.00
0.00
Operating Profit (PBDIT) excl Other Income
-97.00
-78.30
-23.88%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-88.90
-73.90
-20.30%
Operating Profit Margin (Excl OI)
0.00%
0.00%
NA
USD in Million.
Net Sales
QoQ Growth in quarter ended Dec 2025 is 0.00% vs 0.00% in Sep 2025
Consolidated Net Profit
QoQ Growth in quarter ended Dec 2025 is -20.30% vs -3.94% in Sep 2025
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
0.00
8.60
-100.00%
Operating Profit (PBDIT) excl Other Income
-326.10
-199.80
-63.21%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-303.30
-182.80
-65.92%
Operating Profit Margin (Excl OI)
0.00%
-23,402.90%
2,340.29%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is -100.00% vs 258.33% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is -65.92% vs -48.26% in Dec 2024
About Praxis Precision Medicines, Inc. 
Praxis Precision Medicines, Inc.
Pharmaceuticals & Biotechnology
Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in translating genetic insights into the development of therapies for central nervous system (CNS) disorders characterized by neuronal imbalance. Its development stage products include PRAX-114, PRAX-944 and PRAX-562. PRAX-114 is an extrasynaptic-preferring gamma-aminobutyric acid-A (GABAA) receptor positive allosteric modulator (PAM) for the treatment of patients suffering from major depressive disorder (MDD) and perimenopausal depression (PMD). PRAX-944 is a differentiated selective small molecule inhibitor of T-type calcium channel, for the treatment of essential tremor (ET). PRAX-562 is the selective, persistent sodium current blocker in development for the treatment of a range of CNS disorders.
Company Coordinates 
Company Details
101 Main Street, #1210, Suite 1210 , CAMBRIDGE MA : 02142
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