Denali Therapeutics, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US24823R1059
  • NASDAQ: DNLI
USD
20.46
-1.14 (-5.28%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-recommendationScore
Click here to find our call on this stock
Strong Sell
Sell
Hold
Buy
Strong Buy

Comparison

Company
Score
Quality
Valuation
Financial
Technical
Blueprint Medicines Corp.
Krystal Biotech, Inc.
Axsome Therapeutics, Inc.
Denali Therapeutics, Inc.
10X Genomics, Inc.
CRISPR Therapeutics AG
BridgeBio Pharma, Inc.
Arrowhead Pharmaceuticals, Inc.
Immunovant, Inc.
ImmunoGen, Inc.
Mirati Therapeutics, Inc.

Why is Denali Therapeutics, Inc. ?

1
Poor Management Efficiency with a low ROE of 1.05%
  • The company has been able to generate a Return on Equity (avg) of 1.05% signifying low profitability per unit of shareholders funds
2
Positive results in Jun 26
  • NET PROFIT(HY) Higher at USD -256 MM
  • NET SALES(9M) Higher at USD 3.6 MM
  • INVENTORY TURNOVER RATIO(HY) Highest at 7.28 times
3
Risky -
  • The stock is trading risky as compared to its average historical valuations
  • Over the past year, while the stock has generated a return of 56.78%, its profits have fallen by -21.2%
4
Reducing Promoter Confidence
  • Promoters have decreased their stake in the company by -3.62% over the previous quarter and currently hold 1.98% of the company
  • Promoters decreasing their stake may signify reduced confidence in the future of the business
5
Market Beating Performance
  • The stock has generated a return of 56.78% in the last 1 year, much higher than market (S&P 500) returns of 15.76%
stock-recommendationReal-Time Research Report

Verdict Report

How much should you hold?

  1. Overall Portfolio exposure to Denali Therapeutics, Inc. should be less than 10%
  2. Overall Portfolio exposure to Pharmaceuticals & Biotechnology should be less than 30%

(If sector exposure > 30%, please use optimiser tool to see which are the best stocks to hold in Pharmaceuticals & Biotechnology)

When to exit? - We will constantly monitor the company and suggest at the appropriate time to exit from the stock

Is Denali Therapeutics, Inc. for you?

High Risk, Low Return

Absolute
Risk Adjusted
Volatility
Denali Therapeutics, Inc.
56.78%
-0.05
57.60%
S&P 500
15.76%
1.20
13.17%
stock-recommendationQuality
stock-summaryManagement Risk
stock-summaryGrowth
stock-summaryCapital Structure
stock-recommendation
Quality grade scale :

Below Average, Average, Good, Excellent

Quality key factors

Factor
Value
Sales Growth (5y)
-100.00%
EBIT Growth (5y)
-254.68%
EBIT to Interest (avg)
-271.59
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.72
Sales to Capital Employed (avg)
0.21
Tax Ratio
0.01%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
1.05%
stock-recommendationValuation

Valuation Scorecard stock-summary

stock-recommendation
Valuation grade scale :

Very Risky, Risky, Very Expensive, Expensive, Fair, Attractive, Very Attractive

Valuation Key Factors stock-summary

Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
2.84
EV to EBIT
-3.64
EV to EBITDA
-3.72
EV to Capital Employed
13.01
EV to Sales
NA
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-357.30%
ROE (Latest)
-50.56%
stock-recommendationTechnicals

Technical key factors

Indicator
Weekly
Monthly
MACD
Mildly Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Bullish
Moving Averages
Bullish (Daily)
KST
Mildly Bearish
Mildly Bullish
Dow Theory
Mildly Bullish
No Trend
OBV
No Trend
Mildly Bullish
stock-recommendation Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
Technical Movement
stock-recommendationFinancial Trend

Financial Trend Scorecard stock-summary

stock-recommendation
Financial Trend scale:

Very Negative, Negative, Flat, Positive, Very Positive, Outstanding

14What is working for the Company
NET PROFIT(HY)

Higher at USD -256 MM

NET SALES(9M)

Higher at USD 3.6 MM

INVENTORY TURNOVER RATIO(HY)

Highest at 7.28 times

DEBTORS TURNOVER RATIO(HY)

Highest at 1.06 times

OPERATING PROFIT(Q)

Highest at USD -125.14 MM

EPS(Q)

Highest at USD -0.68

-6What is not working for the Company
OPERATING CASH FLOW(Y)

Lowest at USD -434.04 MM

ROCE(HY)

Lowest at -54.93%

RAW MATERIAL COST(Y)

Grown by 5,239% (YoY

CASH AND EQV(HY)

Lowest at USD 1,698.15 MM

Here's what is working for Denali Therapeutics, Inc.

Net Sales
At USD 3.6 MM has Grown at inf%
Year on Year (YoY)
MOJO Watch
Sales trend is very positive

Net Sales (USD MM)

Net Profit
Higher at USD -256 MM
than preceding 12 month period ended Jun 2026
MOJO Watch
In the half year the company has already crossed Net Profit of the previous twelve months

Net Profit (USD MM)

Operating Profit
Highest at USD -125.14 MM
in the last five periods
MOJO Watch
Near term Operating Profit trend is positive

Operating Profit (USD MM)

EPS
Highest at USD -0.68
in the last five periods
MOJO Watch
Increasing profitability; company has created higher earnings for shareholders

EPS (USD)

Inventory Turnover Ratio
Highest at 7.28 times
in the last five Semi-Annual periods
MOJO Watch
Company has been able to sell its inventory faster

Inventory Turnover Ratio

Debtors Turnover Ratio
Highest at 1.06 times
in the last five Semi-Annual periods
MOJO Watch
Company has been able to sell its Debtors faster

Debtors Turnover Ratio

Net Sales
Higher at USD 3.6 MM
than preceding 12 month period ended Jun 2026
MOJO Watch
In the nine month period the company has already crossed sales of the previous twelve months

Net Sales (USD MM)

Depreciation
Highest at USD 5.4 MM
in the last five periods
MOJO Watch
The expenditure on assets done by the company may have gone into operation

Depreciation (USD MM)

Depreciation
At USD 5.4 MM has Grown at 89.77%
period on period (QoQ)
MOJO Watch
The expenditure on assets done by the company has gone into productive use which should positively reflect in the future sales

Depreciation (USD MM)

Here's what is not working for Denali Therapeutics, Inc.

Operating Cash Flow
Lowest at USD -434.04 MM
in the last three years
MOJO Watch
The company's cash revenues from business operations are falling

Operating Cash Flows (USD MM)

Cash and Eqv
Lowest at USD 1,698.15 MM
in the last six Semi-Annual periods
MOJO Watch
Short Term liquidity is deteriorating

Cash and Cash Equivalents

Raw Material Cost
Grown by 5,239% (YoY)
MOJO Watch
The company's ability to pass on the cost of raw materials to customers has deteriorated; this may lead to a fall in profit margin

Raw Material Cost as a percentage of Sales

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