Stoke Therapeutics, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US86150R1077
USD
31.05
1.24 (4.16%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

660.42 k

Shareholding (Mar 2025)

FII

39.20%

Held by 66 FIIs

DII

18.42%

Held by 31 DIIs

Promoter

19.16%

How big is Stoke Therapeutics, Inc.?

22-Jun-2025

As of Jun 18, Stoke Therapeutics, Inc. has a market capitalization of 636.60 million and reported net sales of 190.90 million with a net profit of 50.27 million over the latest four quarters. The balance sheet as of Dec'24 shows shareholder's funds of 229.02 million and total assets of 271.56 million.

As of Jun 18, Stoke Therapeutics, Inc. has a market capitalization of 636.60 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the company reported net sales of 190.90 million for the latest four quarters, along with a net profit of 50.27 million during the same period.<BR><BR>As of Dec'24, the balance sheet shows shareholder's funds of 229.02 million and total assets amounting to 271.56 million.

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What does Stoke Therapeutics, Inc. do?

22-Jun-2025

Stoke Therapeutics, Inc. is a biotechnology company focused on developing treatments for genetic diseases, with a market cap of $636.60 million and recent net sales of $159 million. Key financial metrics include a P/E ratio of 12.00 and a return on equity of 14.36%.

Overview:<BR>Stoke Therapeutics, Inc. is a biotechnology company that develops treatments for genetic diseases, operating within the Pharmaceuticals & Biotechnology industry and categorized as a micro-cap company.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 159 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: 113 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 636.60 Million (Micro Cap)<BR><BR>Key Metrics:<BR>P/E: 12.00 <BR>Dividend Yield: 0.00% <BR>Debt Equity: -1.01 <BR>Return on Equity: 14.36% <BR>Price to Book: 1.82<BR><BR>Contact Details:<BR>Address: 3 Preston Ct, BEDFORD MA: 01730-2379 <BR>Tel: 1 781 4308200 <BR>Fax: 1 302 5313150 <BR>Website: https://www.stoketherapeutics.com/

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Should I buy, sell or hold Stoke Therapeutics, Inc.?

22-Jun-2025

Who are in the management team of Stoke Therapeutics, Inc.?

22-Jun-2025

As of March 2022, the management team of Stoke Therapeutics, Inc. includes Dr. Seth Harrison (Independent Chairman), Dr. Edward Kaye (CEO), and several Independent Directors: Ms. Jennifer Burstein, Prof. Adrian Krainer, Dr. Arthur Levin, Dr. Garry Menzel, and Ms. Julie Smith. They oversee the company's strategic direction and operations.

As of March 2022, the management team of Stoke Therapeutics, Inc. includes the following individuals:<BR><BR>- Dr. Seth Harrison, who serves as the Independent Chairman of the Board.<BR>- Dr. Edward Kaye, who is the Chief Executive Officer and a Director.<BR>- Ms. Jennifer Burstein, who is an Independent Director.<BR>- Prof. Adrian Krainer, who is also an Independent Director.<BR>- Dr. Arthur Levin, serving as an Independent Director.<BR>- Dr. Garry Menzel, who is an Independent Director.<BR>- Ms. Julie Smith, another Independent Director.<BR><BR>This team is responsible for guiding the company's strategic direction and operations.

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Is Stoke Therapeutics, Inc. technically bullish or bearish?

20-Sep-2025

As of September 5, 2025, Stoke Therapeutics, Inc. has a bullish trend supported by positive MACD signals and strong performance, having returned 26.96% over the past month and 113.06% year-to-date, despite some bearish momentum indicated by the weekly RSI and KST.

As of 5 September 2025, the technical trend for Stoke Therapeutics, Inc. has changed from mildly bullish to bullish. The current stance is bullish, supported by bullish signals in the MACD across both weekly and monthly time frames, as well as bullish readings in the Bollinger Bands and On-Balance Volume. However, the weekly RSI indicates bearish momentum, and the KST shows a mildly bearish signal on the monthly chart. The daily moving averages are also bullish, reinforcing the positive outlook.<BR><BR>In terms of performance, Stoke Therapeutics has outperformed the S&P 500 over the past month with a return of 26.96% compared to the S&P's 2.33%, and it has significantly outperformed year-to-date with a return of 113.06% against the S&P's 12.22%.

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Is Stoke Therapeutics, Inc. overvalued or undervalued?

21-Oct-2025

As of October 17, 2025, Stoke Therapeutics, Inc. is considered overvalued with a valuation grade of expensive, reflected in its high P/E ratio of 12 compared to peers, despite a strong year-to-date return of 203.99%.

As of 17 October 2025, the valuation grade for Stoke Therapeutics, Inc. has moved from fair to expensive, indicating that the company is overvalued. Key valuation ratios include a P/E ratio of 12, an EV to EBITDA of 5.94, and a PEG ratio of 0.09, which suggest that while the company has some attractive growth potential, it is currently priced higher than its fundamentals warrant.<BR><BR>In comparison to peers, Stoke Therapeutics has a significantly higher P/E ratio of 22.96 compared to CorMedix, Inc. at 18.60, which is considered very attractive, and Taysha Gene Therapies, Inc. which is deemed risky with a negative P/E. This disparity highlights that Stoke is trading at a premium relative to its more favorably valued peers. Additionally, Stoke Therapeutics has outperformed the S&P 500 over multiple periods, with a year-to-date return of 203.99% compared to the S&P 500's 13.30%, but this strong performance does not mitigate its current overvaluation.

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Dashboard
1

Poor Management Efficiency with a low ROE of 2.87%

  • The company has been able to generate a Return on Equity (avg) of 2.87% signifying low profitability per unit of shareholders funds
2

The company has declared Positive results for the last 4 consecutive quarters

3

With ROE of 14.36%, it has a attractive valuation with a 1.74 Price to Book Value

4

High Institutional Holdings at 100%

5

Market Beating performance in long term as well as near term

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 1,205 Million (Small Cap)

stock-summary
P/E

12.00

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.73

stock-summary
Return on Equity

15.67%

stock-summary
Price to Book

3.60

Revenue and Profits:
Net Sales:
14 Million
(Quarterly Results - Jun 2025)
Net Profit:
-23 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
57.06%
0%
57.06%
6 Months
184.86%
0%
184.86%
1 Year
171.65%
0%
171.65%
2 Years
686.08%
0%
686.08%
3 Years
321.88%
0%
321.88%
4 Years
52.88%
0%
52.88%
5 Years
-34.31%
0%
-34.31%

Stoke Therapeutics, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
188.80%
EBIT Growth (5y)
23.58%
EBIT to Interest (avg)
-67.33
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-1.01
Sales to Capital Employed (avg)
0.17
Tax Ratio
2.48%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
2.87%
Valuation key factors
Factor
Value
P/E Ratio
12
Industry P/E
Price to Book Value
1.74
EV to EBIT
6.62
EV to EBITDA
5.94
EV to Capital Employed
-50.90
EV to Sales
1.33
PEG Ratio
0.09
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
14.36%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
Bearish
Bollinger Bands
Bullish
Mildly Bullish
Moving Averages
Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
Mildly Bullish
Mildly Bullish
OBV
Bullish
Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Foreign Institutions

Domestic Funds

Held in 46 Schemes (23.22%)

Foreign Institutions

Held by 66 Foreign Institutions (39.2%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
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        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -91.30% vs 601.77% in Mar 2025",
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        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is -120.81% vs 1,175.24% in Mar 2025",
        "dir": -1
      }
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          "val2": "112.30",
          "chgp": "-123.33%",
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          "field": "Consolidate Net Profit",
          "val1": "-23.50",
          "val2": "112.90",
          "chgp": "-120.81%",
          "chgp_class": "negative"
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          "field": "Operating Profit Margin (Excl OI)",
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          "field": "Consolidate Net Profit",
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
13.80
158.60
-91.30%
Operating Profit (PBDIT) excl Other Income
-26.20
112.30
-123.33%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-23.50
112.90
-120.81%
Operating Profit Margin (Excl OI)
-1,975.80%
701.50%
-267.73%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is -91.30% vs 601.77% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is -120.81% vs 1,175.24% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
36.60
8.80
315.91%
Operating Profit (PBDIT) excl Other Income
-96.90
-110.00
11.91%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-89.00
-104.70
15.00%
Operating Profit Margin (Excl OI)
-2,773.10%
-13,072.10%
1,029.90%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 315.91% vs -29.03% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 15.00% vs -3.56% in Dec 2023

stock-summaryCompany CV
About Stoke Therapeutics, Inc. stock-summary
stock-summary
Stoke Therapeutics, Inc.
Pharmaceuticals & Biotechnology
Stoke Therapeutics Inc is a biotechnology company that develops treatments for genetic diseases. The Company develops antisense oligonucleotide medicines that target ribo-nucleic acid (RNA) splicing to increase gene expression for the treatment of severe genetic diseases. It uses targeted augmentation of nuclear gene output (TANGO) to effect targeted enhancement of gene expression. It provides TANGO, which is a precision medicine platform for treating a category of genetic diseases, such as autosomal dominant haploinsufficiency. TANGO is designed to address protein deficiency by upregulating target protein expression.
Company Coordinates stock-summary
Company Details
3 Preston Ct , BEDFORD MA : 01730-2379
Registrar Details