Compare Syndax Pharmaceuticals, Inc. with Similar Stocks
Dashboard
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Poor Management Efficiency with a low ROE of 0.83%
- The company has been able to generate a Return on Equity (avg) of 0.83% signifying low profitability per unit of shareholders funds
2
With a growth in Net Sales of 794.9%, the company declared Very Positive results in Sep 25
3
Risky -
4
Rising Promoter Confidence
5
Market Beating Performance
Stock DNA
Pharmaceuticals & Biotechnology
USD 1,711 Million (Small Cap)
NA (Loss Making)
NA
0.00%
-0.79
-269.93%
14.83
Revenue and Profits:
Net Sales:
69 Million
(Quarterly Results - Dec 2025)
Net Profit:
-68 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
17.17%
0%
17.17%
6 Months
53.59%
0%
53.59%
1 Year
92.82%
0%
92.82%
2 Years
-1.67%
0%
-1.67%
3 Years
8.63%
0%
8.63%
4 Years
38.22%
0%
38.22%
5 Years
1.26%
0%
1.26%
Syndax Pharmaceuticals, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
136.12%
EBIT Growth (5y)
-221.63%
EBIT to Interest (avg)
-75.64
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.78
Sales to Capital Employed (avg)
0.09
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0.83%
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
8.52
EV to EBIT
-3.63
EV to EBITDA
-3.63
EV to Capital Employed
26.52
EV to Sales
15.74
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-730.36%
ROE (Latest)
-212.79%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Bullish
Moving Averages
Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
Mildly Bullish
Mildly Bullish
OBV
Mildly Bullish
Mildly Bearish
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Domestic Funds
Domestic Funds
Held in 64 Schemes (33.4%)
Foreign Institutions
Held by 115 Foreign Institutions (15.29%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - YoY
Dec'25
Dec'24
Change(%)
Net Sales
68.70
7.70
792.21%
Operating Profit (PBDIT) excl Other Income
-62.50
-96.40
35.17%
Interest
9.60
4.80
100.00%
Exceptional Items
0.00
0.00
Consolidate Net Profit
-68.00
-94.20
27.81%
Operating Profit Margin (Excl OI)
-910.10%
-12,547.50%
1,163.74%
USD in Million.
Net Sales
YoY Growth in quarter ended Dec 2025 is 792.21% vs 0.00% in Dec 2024
Consolidated Net Profit
YoY Growth in quarter ended Dec 2025 is 27.81% vs -29.93% in Dec 2024
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
172.40
23.70
627.43%
Operating Profit (PBDIT) excl Other Income
-273.10
-339.70
19.61%
Interest
33.80
4.90
589.80%
Exceptional Items
0.00
0.00
Consolidate Net Profit
-285.40
-318.80
10.48%
Operating Profit Margin (Excl OI)
-1,584.50%
-14,344.30%
1,275.98%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 627.43% vs 0.00% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 10.48% vs -52.24% in Dec 2024
About Syndax Pharmaceuticals, Inc. 
Syndax Pharmaceuticals, Inc.
Pharmaceuticals & Biotechnology
Syndax Pharmaceuticals, Inc. is a clinical stage biopharmaceutical company focused on developing a pipeline of combination therapies in multiple cancer indications. The Company’s product candidate, entinostat, is a once-weekly, oral, small molecule, Class I histone deacetylases (HDAC) inhibitor that being evaluated in the Phase III E2112 registrational clinical trial in combination with exemestane for hormone receptor positive, human epidermal growth factor receptor 2 negative, and breast cancer. The Company’s clinical-stage product candidate, SNDX-5613, is the orally available, small molecule inhibitor of the interaction of menin with the mixed lineage leukemia protein (MLL). It is developing SNDX-5613 as a targeted therapy to treat two genetically defined acute leukemias: mixed lineage leukemia-rearranged (MLLr), and acute myeloid leukemia (AML), with a mutated nucleophosmin 1. It is also developing SNDX-6352, a monoclonal antibody targeting the colony stimulating factor-1 receptor.
Company Coordinates 
Company Details
Building D, 35 Gatehouse Dr Fl 3 , WALTHAM MA : 02451-1215
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