uniQure NV

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: NL0010696654
USD
22.74
-2.58 (-10.19%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

2.2 M

Shareholding (Mar 2025)

FII

20.76%

Held by 91 FIIs

DII

47.0%

Held by 36 DIIs

Promoter

4.41%

How big is uniQure NV?

22-Jun-2025

As of Jun 18, uniQure NV has a market capitalization of 809.73 million, with net sales of 20.21 million and a net profit of -217.58 million over the last four quarters. The balance sheet shows shareholder's funds of -6.75 million and total assets of 556.54 million.

As of Jun 18, uniQure NV has a market capitalization of 809.73 million, categorizing it as a Micro Cap company.<BR><BR>As of the latest four quarters, uniQure NV reported net sales of 20.21 million and a net profit of -217.58 million.<BR><BR>As of Dec 24, the balance sheet shows shareholder's funds of -6.75 million and total assets of 556.54 million.

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What does uniQure NV do?

22-Jun-2025

uniQure NV is a Netherlands-based biotechnology company focused on developing gene therapies for genetic diseases, with recent net sales of $2 million and a net loss of $44 million. The company has a market cap of $809.73 million and does not currently pay dividends.

Overview:<BR>uniQure NV is a Netherlands-based company specializing in gene therapy within the Pharmaceuticals & Biotechnology industry, focusing on developing one-time administered treatments for genetic and other devastating diseases.<BR><BR>Financial Snapshot:<BR>Most recent Net Sales: 2 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -44 Million (Quarterly Results - Mar 2025) <BR>Market cap: USD 809.73 Million (Micro Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: 2.76 <BR>Return on Equity: -666.88% <BR>Price to Book: 24.04<BR><BR>Contact Details:<BR>Address: Paasheuvelweg 25a, AMSTERDAM None: 1105 BP <BR>Tel: ['31 20 2406000', '1 339 9707536'] <BR>Fax: 31 20 2406020 <BR>Website: http://www.uniqure.com/

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Who are in the management team of uniQure NV?

22-Jun-2025

As of March 2022, the management team of uniQure NV includes CEO Matthew Kapusta, along with other executives and non-executive directors such as Philip Astley-Sparke (Chairman), Robert Gut, Leonard Post, Madhavan Balachandran, Jack Kaye, and David Meek.

As of March 2022, the management team of uniQure NV includes the following individuals:<BR><BR>- Mr. Philip Astley-Sparke: Independent Non-Executive Chairman of the Board<BR>- Mr. Matthew Kapusta: Chief Executive Officer, Chief Financial Officer, Executive Director<BR>- Dr. Robert Gut: Executive Director<BR>- Dr. Leonard Post: Director<BR>- Mr. Madhavan Balachandran: Non-Executive Independent Director<BR>- Mr. Jack Kaye: Non-Executive Independent Director<BR>- Mr. David Meek: Non-Executive Independent Director<BR><BR>In summary, the management team comprises a mix of executive and non-executive directors, with Mr. Matthew Kapusta serving in a dual role as CEO and CFO.

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Should I buy, sell or hold uniQure NV?

22-Jun-2025

Is uniQure NV overvalued or undervalued?

20-Sep-2025

As of August 8, 2022, uniQure NV's valuation has shifted from fair to risky due to significant negative financial metrics, including a Price to Book Value of 28.07, an EV to EBITDA of -6.16, and a return on equity of -666.88%, making it appear overvalued despite a disappointing year-to-date stock performance of -16.53%.

As of 8 August 2022, the valuation grade for uniQure NV moved from fair to risky, indicating a deterioration in its investment appeal. The company appears to be overvalued given its significant negative financial metrics, including a Price to Book Value of 28.07 and an EV to EBITDA of -6.16. Additionally, its return on equity (ROE) stands at a staggering -666.88%, further highlighting its struggles.<BR><BR>In comparison to its peer, Precigen, Inc., which has a worse EV to EBITDA ratio of -13.1325, uniQure's valuation metrics still suggest it is not a favorable investment. The company's recent stock performance has been disappointing, with a year-to-date return of -16.53% compared to the S&P 500's positive return of 12.22%, reinforcing the notion that uniQure is currently overvalued.

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Is uniQure NV technically bullish or bearish?

20-Sep-2025

As of August 28, 2025, uniQure NV shows a bullish trend with positive MACD and OBV indicators, but mixed signals from RSI and Bollinger Bands suggest caution, especially given its underperformance against the S&P 500.

As of 28 August 2025, the technical trend for uniQure NV has changed from mildly bullish to bullish. The MACD is bullish on both the weekly and monthly time frames, indicating positive momentum. However, the RSI shows a bearish signal on the monthly, which suggests some caution. The Bollinger Bands are bearish weekly but mildly bullish monthly, indicating mixed signals. Moving averages are mildly bullish daily, while the KST is mildly bearish weekly but bullish monthly. Dow Theory supports a mildly bullish stance on both weekly and monthly charts, and OBV is bullish monthly, further supporting the positive outlook.<BR><BR>Despite the current bullish trend, the stock has underperformed against the S&P 500 across multiple periods, with a year-to-date return of -16.53% compared to the S&P 500's 12.22%, and a 5-year return of -64.64% versus the S&P 500's 96.61%. Overall, the technical stance is bullish but with some mixed indicators suggesting caution.

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iScoreScore
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Strong Sell
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Strong Buy

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Dashboard
1

With a Operating Losses, the company has a Weak Long Term Fundamental Strength

  • Company's ability to service its debt is weak with a poor EBIT to Interest (avg) ratio of -1.19
2

Negative results in Jun 25

3

Risky - Negative EBITDA

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 956 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-33.48

stock-summary
Return on Equity

5,046.81%

stock-summary
Price to Book

-238.90

Revenue and Profits:
Net Sales:
5 Million
(Quarterly Results - Jun 2025)
Net Profit:
-38 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
30.84%
0%
30.84%
6 Months
50.0%
0%
50.0%
1 Year
254.76%
0%
254.76%
2 Years
218.49%
0%
218.49%
3 Years
-12.64%
0%
-12.64%
4 Years
-16.21%
0%
-16.21%
5 Years
-54.96%
0%
-54.96%

uniQure NV for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
21.98%
EBIT Growth (5y)
-7.26%
EBIT to Interest (avg)
-1.19
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
2.76
Sales to Capital Employed (avg)
0.08
Tax Ratio
1.00%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
42.66%
ROE (avg)
11.19%
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
28.07
EV to EBIT
-5.67
EV to EBITDA
-6.16
EV to Capital Employed
8.20
EV to Sales
51.41
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-144.66%
ROE (Latest)
-666.88%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bearish
Mildly Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Bullish
Bullish
Dow Theory
No Trend
Mildly Bullish
OBV
Mildly Bullish
Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Domestic Funds

Domestic Funds

Held in 33 Schemes (27.69%)

Foreign Institutions

Held by 91 Foreign Institutions (20.76%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
[
  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - YoY",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in quarter ended Jun 2025 is -52.25% vs 362.50% in Jun 2024",
        "dir": -1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in quarter ended Jun 2025 is 33.04% vs 17.81% in Jun 2024",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Jun'24",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "5.30",
          "val2": "11.10",
          "chgp": "-52.25%",
          "chgp_class": "negative"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-40.60",
          "val2": "-44.70",
          "chgp": "9.17%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "15.60",
          "val2": "16.20",
          "chgp": "-3.70%",
          "chgp_class": "positive"
        },
        {
          "field": "Exceptional Items",
          "val1": "-2.30",
          "val2": "1.80",
          "chgp": "-227.78%",
          "chgp_class": "negative"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-37.70",
          "val2": "-56.30",
          "chgp": "33.04%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-8,401.40%",
          "val2": "-4,259.90%",
          "chgp": "-414.15%",
          "chgp_class": "negative"
        }
      ]
    }
  },
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    "link": "annual",
    "btn_text": "All Annual Results",
    "header": "Annual Results Snapshot (Consolidated) - Dec'24",
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      {
        "prefix": "Net Sales ",
        "suffix": "YoY Growth in year ended Dec 2024 is 71.52% vs -85.16% in Dec 2023",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is 22.33% vs -143.30% in Dec 2023",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Dec'24",
        "Dec'23",
        "Change(%)"
      ],
      "body": [
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          "field": "Net Sales",
          "val1": "27.10",
          "val2": "15.80",
          "chgp": "71.52%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "-171.60",
          "val2": "-259.40",
          "chgp": "33.85%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "63.70",
          "val2": "41.60",
          "chgp": "53.12%",
          "chgp_class": "negative"
        },
        {
          "field": "Exceptional Items",
          "val1": "-3.70",
          "val2": "-15.60",
          "chgp": "76.28%",
          "chgp_class": "positive"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "-239.60",
          "val2": "-308.50",
          "chgp": "22.33%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-6,795.00%",
          "val2": "-17,127.10%",
          "chgp": "1,033.21%",
          "chgp_class": "positive"
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      ]
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  }
]
Quarterly Results Snapshot (Consolidated) - Jun'25 - YoYstock-summary
Jun'25
Jun'24
Change(%)
Net Sales
5.30
11.10
-52.25%
Operating Profit (PBDIT) excl Other Income
-40.60
-44.70
9.17%
Interest
15.60
16.20
-3.70%
Exceptional Items
-2.30
1.80
-227.78%
Consolidate Net Profit
-37.70
-56.30
33.04%
Operating Profit Margin (Excl OI)
-8,401.40%
-4,259.90%
-414.15%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in quarter ended Jun 2025 is -52.25% vs 362.50% in Jun 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in quarter ended Jun 2025 is 33.04% vs 17.81% in Jun 2024

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
27.10
15.80
71.52%
Operating Profit (PBDIT) excl Other Income
-171.60
-259.40
33.85%
Interest
63.70
41.60
53.12%
Exceptional Items
-3.70
-15.60
76.28%
Consolidate Net Profit
-239.60
-308.50
22.33%
Operating Profit Margin (Excl OI)
-6,795.00%
-17,127.10%
1,033.21%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 71.52% vs -85.16% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is 22.33% vs -143.30% in Dec 2023

stock-summaryCompany CV
About uniQure NV stock-summary
stock-summary
uniQure NV
Pharmaceuticals & Biotechnology
Uniqure NV is a company based in the Netherlands specialized in gene therapy. It seeks to develop one-time administered treatments with potentially curative results for patients suffering from genetic and other devastating diseases. It develops, both internally and through partnerships, a pipeline of gene therapies. It produces adeno-associated virus based, or AAV-based, gene therapies in its own facilities with a proprietary, commercial-scale, current good manufacturing practices, compliant, manufacturing process. AMT-061, the Company’s lead product candidate for patients with hemophilia B, is going through a dosing phase of a pivotal study. AMT-130, the product candidate for patients with Huntington’s disease is in Phase I/II clinical study.
Company Coordinates stock-summary
Company Details
Paasheuvelweg 25a , AMSTERDAM None : 1105 BP
stock-summary
Tel: 31 20 24060001 339 9707536
stock-summary
Registrar Details