Zymeworks, Inc.

  • Market Cap: Small Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US98985Y1082
USD
26.52
1.42 (5.66%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

237.76 k

Shareholding (Mar 2025)

FII

21.45%

Held by 104 FIIs

DII

62.7%

Held by 21 DIIs

Promoter

2.66%

How big is Zymeworks, Inc.?

22-Jun-2025

As of Jun 18, Zymeworks, Inc. has a market capitalization of 859.90 million and reported net sales of 93.38 million, with a net profit loss of 113.69 million over the latest four quarters.

As of Jun 18, Zymeworks, Inc. has a market capitalization of 859.90 million, categorizing it as a Micro Cap company.<BR><BR>As of Jun 18, the company reported net sales of 93.38 million for the latest four quarters. However, it also experienced a net profit loss of 113.69 million during the same period.<BR><BR>As of Dec 24, the balance sheet shows shareholder's funds of 338.77 million and total assets amounting to 463.09 million.

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What does Zymeworks, Inc. do?

22-Jun-2025

Zymeworks, Inc. is a clinical-stage biopharmaceutical company focused on developing bio-therapeutics for cancer treatment, with a market cap of approximately $859.90 million. As of March 2025, it reported net sales of $27 million and a net loss of $23 million.

Overview: <BR>Zymeworks, Inc. is a clinical-stage biopharmaceutical company engaged in the discovery, development, and commercialization of bio-therapeutics for the treatment of cancer, operating within the Pharmaceuticals & Biotechnology industry and classified as a micro-cap company.<BR><BR>Financial Snapshot: <BR>Most recent Net Sales: 27 Million (Quarterly Results - Mar 2025) <BR>Most recent Net Profit: -23 Million (Quarterly Results - Mar 2025) <BR>Market-cap: USD 859.90 Million (Micro Cap)<BR><BR>Key Metrics: <BR>P/E: NA (Loss Making) <BR>Industry P/E: NA <BR>Dividend Yield: 0.00% <BR>Debt Equity: -0.81 <BR>Return on Equity: -29.66% <BR>Price to Book: 2.65<BR><BR>Contact Details: <BR>Address: 540-1385 West 8Th Avenue, VANCOUVER BC: V6H 3V9 <BR>Tel: 1 604 6781388 <BR>Website: https://www.zymeworks.com/

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Should I buy, sell or hold Zymeworks, Inc.?

22-Jun-2025

Is Zymeworks, Inc. overvalued or undervalued?

25-Jun-2025

As of March 6, 2024, Zymeworks, Inc. is considered overvalued with a risky valuation grade, reflected by a price-to-book ratio of 2.72, an EV to EBITDA of -6.53, a ROCE of -171.02%, and a year-to-date return of -14.82%, contrasting sharply with its peers and the S&P 500's performance.

As of 6 March 2024, Zymeworks, Inc. has moved from an attractive to a risky valuation grade, indicating a shift in investor sentiment towards the company. The current analysis suggests that Zymeworks is overvalued given its financial metrics. The price-to-book value stands at 2.72, while the EV to EBITDA ratio is -6.53, and the ROCE is a concerning -171.02%. <BR><BR>In comparison to its peers, Zymeworks' valuation ratios are significantly weaker; for instance, Harrow, Inc. has an EV to EBITDA of 60.41, while Evolus, Inc. shows an EV to EBITDA of -21.94, both indicating more favorable valuations in their respective contexts. Additionally, Zymeworks' recent stock performance has been underwhelming, with a year-to-date return of -14.82%, contrasting with a 2.44% gain in the S&P 500, further reinforcing the notion of overvaluation in light of its current financial struggles.

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Is Zymeworks, Inc. technically bullish or bearish?

20-Sep-2025

As of August 25, 2025, Zymeworks, Inc. has a bullish technical trend supported by strong indicators, outperforming the S&P 500 with a 17.37% return over the past month and 31.71% over the past year.

As of 25 August 2025, the technical trend for Zymeworks, Inc. has changed from mildly bullish to bullish. The current stance is bullish with strong indicators supporting this view. The MACD is bullish on both the weekly and monthly time frames, and Bollinger Bands also indicate bullish momentum. Daily moving averages are bullish, and the On-Balance Volume (OBV) is bullish as well. However, the KST shows a mildly bearish signal on the monthly, and Dow Theory indicates a mildly bullish stance on both weekly and monthly time frames.<BR><BR>In terms of performance, Zymeworks has outperformed the S&P 500 over the past month with a return of 17.37% compared to the S&P 500's 2.33%, and it has also shown strong returns over the past year at 31.71% versus 17.14% for the benchmark.

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iScoreScore
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Strong Sell
Sell
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Strong Buy

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Dashboard
1

Poor Management Efficiency with a low ROE of 7.29%

  • The company has been able to generate a Return on Equity (avg) of 7.29% signifying low profitability per unit of shareholders funds
2

Positive results in Jun 25

3

Risky - Negative EBITDA

4

Reducing Promoter Confidence

5

Market Beating performance in long term as well as near term

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 1,150 Million (Small Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.83

stock-summary
Return on Equity

-22.02%

stock-summary
Price to Book

3.44

Revenue and Profits:
Net Sales:
49 Million
(Quarterly Results - Jun 2025)
Net Profit:
2 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
87.55%
0%
87.55%
6 Months
119.54%
0%
119.54%
1 Year
90.11%
0%
90.11%
2 Years
189.84%
0%
189.84%
3 Years
249.87%
0%
249.87%
4 Years
43.43%
0%
43.43%
5 Years
-51.25%
0%
-51.25%

Zymeworks, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
32.25%
EBIT Growth (5y)
9.16%
EBIT to Interest (avg)
-104.04
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.81
Sales to Capital Employed (avg)
0.45
Tax Ratio
6.07%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
25.85%
ROE (avg)
7.29%
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
2.72
EV to EBIT
-5.79
EV to EBITDA
-6.53
EV to Capital Employed
9.90
EV to Sales
6.67
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-171.02%
ROE (Latest)
-29.66%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bullish
Bullish
Moving Averages
Bullish (Daily)
KST
Bullish
Bullish
Dow Theory
Mildly Bullish
Mildly Bullish
OBV
No Trend
Mildly Bearish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Foreign Institutions

Domestic Funds

Held in 50 Schemes (13.19%)

Foreign Institutions

Held by 104 Foreign Institutions (21.45%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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  {
    "link": "quarterly",
    "btn_text": "All Quarterly Results",
    "header": "Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQ",
    "rhs": [
      {
        "prefix": "Net Sales ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 79.70% vs -12.58% in Mar 2025",
        "dir": 1
      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "QoQ Growth in quarter ended Jun 2025 is 110.18% vs 3.83% in Mar 2025",
        "dir": 1
      }
    ],
    "table": {
      "header": [
        "Jun'25",
        "Mar'25",
        "Change(%)"
      ],
      "body": [
        {
          "field": "Net Sales",
          "val1": "48.70",
          "val2": "27.10",
          "chgp": "79.70%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit (PBDIT) excl Other Income",
          "val1": "2.50",
          "val2": "-22.30",
          "chgp": "111.21%",
          "chgp_class": "positive"
        },
        {
          "field": "Interest",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Exceptional Items",
          "val1": "0.00",
          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
        },
        {
          "field": "Consolidate Net Profit",
          "val1": "2.30",
          "val2": "-22.60",
          "chgp": "110.18%",
          "chgp_class": "positive"
        },
        {
          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-13.80%",
          "val2": "-944.80%",
          "chgp": "93.10%",
          "chgp_class": "positive"
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      },
      {
        "prefix": "Consolidated Net Profit ",
        "suffix": "YoY Growth in year ended Dec 2024 is -3.37% vs -195.49% in Dec 2023",
        "dir": 1
      }
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    "table": {
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        "Dec'24",
        "Dec'23",
        "Change(%)"
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          "val2": "76.00",
          "chgp": "0.39%",
          "chgp_class": "positive"
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          "field": "Operating Profit (PBDIT) excl Other Income",
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          "field": "Interest",
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          "val2": "0.00",
          "chgp": "",
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        {
          "field": "Exceptional Items",
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          "val2": "0.00",
          "chgp": "",
          "chgp_class": "neutral"
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          "field": "Consolidate Net Profit",
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          "field": "Operating Profit Margin (Excl OI)",
          "val1": "-1,570.30%",
          "val2": "-1,816.20%",
          "chgp": "24.59%",
          "chgp_class": "positive"
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Quarterly Results Snapshot (Consolidated) - Jun'25 - QoQstock-summary
Jun'25
Mar'25
Change(%)
Net Sales
48.70
27.10
79.70%
Operating Profit (PBDIT) excl Other Income
2.50
-22.30
111.21%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
2.30
-22.60
110.18%
Operating Profit Margin (Excl OI)
-13.80%
-944.80%
93.10%
USD in Million.
Direction Arrows
Net Sales

QoQ Growth in quarter ended Jun 2025 is 79.70% vs -12.58% in Mar 2025

Direction Arrows
Consolidated Net Profit

QoQ Growth in quarter ended Jun 2025 is 110.18% vs 3.83% in Mar 2025

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
76.30
76.00
0.39%
Operating Profit (PBDIT) excl Other Income
-108.60
-120.70
10.02%
Interest
0.00
0.00
Exceptional Items
-17.30
0.00
Consolidate Net Profit
-122.70
-118.70
-3.37%
Operating Profit Margin (Excl OI)
-1,570.30%
-1,816.20%
24.59%
USD in Million.
Direction Arrows
Net Sales

YoY Growth in year ended Dec 2024 is 0.39% vs -81.58% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is -3.37% vs -195.49% in Dec 2023

stock-summaryCompany CV
About Zymeworks, Inc. stock-summary
stock-summary
Zymeworks, Inc.
Pharmaceuticals & Biotechnology
Zymeworks Inc. a clinical-stage biopharmaceutical company that is engaged in the discovery, development, and commercialization of bio-therapeutics for the treatment of cancer in Canada. The Company operates through a number of platforms, including Azymetric, which is a bispecific platform enables therapeutic antibodies to simultaneously bind multiple distinct locations on a target or to multiple targets; ZymeLink, which is an antibody-drug conjugate (ADC) platform comprised of cytotoxins and the linker technology used to couple these cytotoxins to tumor-targeting antibodies or proteins, and EFECT, which enables finely tuned modulation (both up and down) of immune cell recruitment and function. Its lead product candidate is ZW25, a bispecific antibody that targets two distinct domains of the human epidermal growth factor receptor 2 (HER2). It product candidate ZW49, combines the design of ZW25 with its ZymeLink ADC platform, comprised of its cytotoxin and cleavable linker.
Company Coordinates stock-summary
Company Details
540-1385 West 8Th Avenue , VANCOUVER BC : V6H 3V9
stock-summary
Tel: 1 604 6781388
stock-summary
Registrar Details