Compare Zymeworks, Inc. with Similar Stocks
Dashboard
1
Poor Management Efficiency with a low ROE of 7.29%
- The company has been able to generate a Return on Equity (avg) of 7.29% signifying low profitability per unit of shareholders funds
2
With a growth in Operating Profit of 151.7%, the company declared Very Positive results in Sep 25
3
Risky -
4
Rising Promoter Confidence
5
Market Beating Performance
Stock DNA
Pharmaceuticals & Biotechnology
USD 1,755 Million (Small Cap)
NA (Loss Making)
NA
0.00%
-0.78
-19.82%
5.48
Revenue and Profits:
Net Sales:
3 Million
(Quarterly Results - Dec 2025)
Net Profit:
-41 Million
Total Returns (Price + Dividend) 
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
-11.67%
0%
-11.67%
6 Months
41.42%
0%
41.42%
1 Year
88.98%
0%
88.98%
2 Years
117.74%
0%
117.74%
3 Years
178.95%
0%
178.95%
4 Years
222.99%
0%
222.99%
5 Years
-26.78%
0%
-26.78%
Zymeworks, Inc. for the last several years.
Risk Adjusted Returns v/s 
News
No Recent News for the Company
Announcements 
No announcement available
Corporate Actions 
No corporate action available
Quality key factors 
Factor
Value
Sales Growth (5y)
39.84%
EBIT Growth (5y)
10.99%
EBIT to Interest (avg)
-104.04
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.81
Sales to Capital Employed (avg)
0.40
Tax Ratio
6.07%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
25.85%
ROE (avg)
7.29%
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
5.48
EV to EBIT
-21.33
EV to EBITDA
-26.05
EV to Capital Employed
21.06
EV to Sales
11.20
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
-98.72%
ROE (Latest)
-19.82%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Bullish
RSI
No Signal
No Signal
Bollinger Bands
Mildly Bearish
Bullish
Moving Averages
Mildly Bullish (Daily)
KST
Mildly Bearish
Bullish
Dow Theory
No Trend
Mildly Bearish
OBV
No Trend
Bullish
Shareholding Snapshot : Dec 2025
Shareholding Compare (%holding) 
Majority shareholders
Foreign Institutions
Domestic Funds
Held in 53 Schemes (15.54%)
Foreign Institutions
Held by 114 Foreign Institutions (16.14%)
Strategic Entities with highest holding
Highest Public shareholder
Quarterly Results Snapshot (Consolidated) - Dec'25 - QoQ
Dec'25
Sep'25
Change(%)
Net Sales
2.50
27.60
-90.94%
Operating Profit (PBDIT) excl Other Income
-42.50
-19.50
-117.95%
Interest
0.00
0.00
Exceptional Items
-0.30
0.00
Consolidate Net Profit
-41.20
-19.60
-110.20%
Operating Profit Margin (Excl OI)
-17,555.50%
-800.70%
-1,675.48%
USD in Million.
Net Sales
QoQ Growth in quarter ended Dec 2025 is -90.94% vs -43.33% in Sep 2025
Consolidated Net Profit
QoQ Growth in quarter ended Dec 2025 is -110.20% vs -952.17% in Sep 2025
Annual Results Snapshot (Consolidated) - Dec'25
Dec'25
Dec'24
Change(%)
Net Sales
106.00
76.30
38.93%
Operating Profit (PBDIT) excl Other Income
-81.80
-108.60
24.68%
Interest
0.00
0.00
Exceptional Items
-0.30
-17.30
98.27%
Consolidate Net Profit
-81.10
-122.70
33.90%
Operating Profit Margin (Excl OI)
-873.40%
-1,570.30%
69.69%
USD in Million.
Net Sales
YoY Growth in year ended Dec 2025 is 38.93% vs 0.39% in Dec 2024
Consolidated Net Profit
YoY Growth in year ended Dec 2025 is 33.90% vs -3.37% in Dec 2024
About Zymeworks, Inc. 
Zymeworks, Inc.
Pharmaceuticals & Biotechnology
Zymeworks Inc. a clinical-stage biopharmaceutical company that is engaged in the discovery, development, and commercialization of bio-therapeutics for the treatment of cancer in Canada. The Company operates through a number of platforms, including Azymetric, which is a bispecific platform enables therapeutic antibodies to simultaneously bind multiple distinct locations on a target or to multiple targets; ZymeLink, which is an antibody-drug conjugate (ADC) platform comprised of cytotoxins and the linker technology used to couple these cytotoxins to tumor-targeting antibodies or proteins, and EFECT, which enables finely tuned modulation (both up and down) of immune cell recruitment and function. Its lead product candidate is ZW25, a bispecific antibody that targets two distinct domains of the human epidermal growth factor receptor 2 (HER2). It product candidate ZW49, combines the design of ZW25 with its ZymeLink ADC platform, comprised of its cytotoxin and cleavable linker.
Company Coordinates 
Company Details
540-1385 West 8Th Avenue , VANCOUVER BC : V6H 3V9
Registrar Details






