Is Karyopharm Therapeutics, Inc. technically bullish or bearish?
2025-09-20 19:45:43As of 13 August 2025, the technical trend for Karyopharm Therapeutics, Inc. has changed from bearish to mildly bearish. Currently, the weekly MACD and Bollinger Bands indicate a mildly bullish stance, while the daily moving averages and the weekly KST suggest a mildly bearish outlook. The RSI shows no signal in both weekly and monthly time frames, and Dow Theory reflects a mildly bearish trend on the weekly chart with no trend on the monthly. In terms of performance, Karyopharm has significantly underperformed the S&P 500 across multiple periods, with a year-to-date return of -43.52% compared to the S&P 500's 12.22%, and a one-year return of -48.13% versus 17.14% for the benchmark. Overall, the current technical stance is mildly bearish, indicating some weakness despite a few bullish signals....
Read MoreIs Karyopharm Therapeutics, Inc. overvalued or undervalued?
2025-09-20 18:20:46As of 15 March 2018, Karyopharm Therapeutics, Inc. has moved from a grade of does not qualify to risky, indicating increased concerns about its valuation. The company appears to be overvalued given its negative valuation metrics, including a Price to Book Value of -0.19, an EV to EBIT of -1.25, and an EV to EBITDA of -1.26. Compared to peers, Karyopharm's EV to EBITDA ratio of -1.6265 is significantly worse than XOMA Corp.'s -22.9484 and Zevra Therapeutics, Inc.'s 7.4373, highlighting its relative weakness in the industry. The stock's performance has been notably poor, with a year-to-date return of -43.52% compared to the S&P 500's 12.22%, and a staggering decline of -97.66% over the past five years, while the S&P 500 has gained 96.61%. This stark contrast in returns further reinforces the notion that Karyopharm is overvalued in its current state....
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