Comparison
Company
Score
Quality
Valuation
Financial
Technical
Why is Karyopharm Therapeutics, Inc. ?
1
With a Negative Book Value, the company has a Weak Long Term Fundamental Strength
- Poor long term growth as Operating profit has grown by an annual rate 8.04% of over the last 5 years
- Company's ability to service its debt is weak with a poor EBIT to Interest (avg) ratio of -4.72
2
Flat results in Dec 25
- CASH AND EQV(HY) Lowest at USD 109.62 MM
- INTEREST(Q) Highest at USD 12.62 MM
- PRE-TAX PROFIT(Q) Lowest at USD -39.9 MM
3
Risky -
- The stock is trading risky as compared to its average historical valuations
- Over the past year, while the stock has generated a return of 30.87%, its profits have fallen by -10.5%
How much should you sell?
- All quantity irrespective of whether you are making profits or losses
(If sector exposure > 30%, please use optimiser tool to see which are the best stocks to hold in Pharmaceuticals & Biotechnology)
When to re-enter? - We will constantly monitor the company and review our call based on new data
Is Karyopharm Therapeutics, Inc. for you?
High Risk, Low Return
Absolute
Risk Adjusted
Volatility
Karyopharm Therapeutics, Inc.
3.74%
-0.47
100.46%
S&P 500
16.12%
0.77
19.29%
Quality key factors
Factor
Value
Sales Growth (5y)
6.21%
EBIT Growth (5y)
8.04%
EBIT to Interest (avg)
-4.72
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.54
Sales to Capital Employed (avg)
10.63
Tax Ratio
0.04%
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
40.76%
ROCE (avg)
0
ROE (avg)
0
Valuation Key Factors 
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
-0.54
EV to EBIT
-3.54
EV to EBITDA
-3.55
EV to Capital Employed
-2.49
EV to Sales
2.20
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
Negative BV
Technical key factors
Indicator
Weekly
Monthly
MACD
Mildly Bearish
Mildly Bullish
RSI
No Signal
No Signal
Bollinger Bands
Bearish
Bearish
Moving Averages
Mildly Bullish (Daily)
KST
Bullish
Bearish
Dow Theory
Mildly Bearish
No Trend
OBV
No Trend
Mildly Bullish
Technical Movement
6What is working for the Company
OPERATING CASH FLOW(Y)
Highest at USD -75.37 MM
NET PROFIT(HY)
Higher at USD -72.96 MM
RAW MATERIAL COST(Y)
Fallen by -0.22% (YoY
DEBTORS TURNOVER RATIO(HY)
Highest at 5.13 times
-11What is not working for the Company
CASH AND EQV(HY)
Lowest at USD 109.62 MM
INTEREST(Q)
Highest at USD 12.62 MM
PRE-TAX PROFIT(Q)
Lowest at USD -39.9 MM
NET PROFIT(Q)
Lowest at USD -39.83 MM
EPS(Q)
Lowest at USD -5.71
Here's what is working for Karyopharm Therapeutics, Inc.
Operating Cash Flow
Highest at USD -75.37 MM
in the last three yearsMOJO Watch
The company has generated higher cash revenues from business operations
Operating Cash Flows (USD MM)
Debtors Turnover Ratio
Highest at 5.13 times
in the last five Semi-Annual periodsMOJO Watch
Company has been able to sell its Debtors faster
Debtors Turnover Ratio
Raw Material Cost
Fallen by -0.22% (YoY)
MOJO Watch
The company's ability to pass on the cost of raw materials to customers has improved; this may lead to a rise in profit margin
Raw Material Cost as a percentage of Sales
Here's what is not working for Karyopharm Therapeutics, Inc.
Interest
At USD 12.62 MM has Grown at 14.63%
period on period (QoQ)MOJO Watch
Rising interest cost signifies increased borrowings
Interest Paid (USD MM)
Interest
Highest at USD 12.62 MM
in the last five periods and Increased by 14.63% (QoQ)MOJO Watch
Rising interest cost signifies increased borrowings
Interest Paid (USD MM)
Pre-Tax Profit
Lowest at USD -39.9 MM
in the last five periodsMOJO Watch
Near term Pre-Tax Profit trend is negative
Pre-Tax Profit (USD MM)
Pre-Tax Profit
At USD -39.9 MM has Fallen at -28.07%
over average net sales of the previous four periods of USD -31.15 MMMOJO Watch
Near term Pre-Tax Profit trend is negative
Pre-Tax Profit (USD MM)
Net Profit
Lowest at USD -39.83 MM
in the last five periodsMOJO Watch
Near term Net Profit trend is negative
Net Profit (USD MM)
Net Profit
At USD -39.83 MM has Fallen at -27.85%
over average net sales of the previous four periods of USD -31.16 MMMOJO Watch
Near term Net Profit trend is negative
Net Profit (USD MM)
EPS
Lowest at USD -5.71
in the last five periodsMOJO Watch
Declining profitability; company has created lower earnings for shareholders
EPS (USD)
Cash and Eqv
Lowest at USD 109.62 MM
in the last six Semi-Annual periodsMOJO Watch
Short Term liquidity is deteriorating
Cash and Cash Equivalents






