Prelude Therapeutics, Inc.

  • Market Cap: Micro Cap
  • Industry: Pharmaceuticals & Biotechnology
  • ISIN: US74065P1012
USD
1.54
0.2 (14.5%)
  • Price Points
  • Score
  • Mojo Parameters
  • Total Return
  • News and Corporate Actions
  • Key factors
  • Shareholding
  • Financials
  • CompanyCV
stock-summaryPrice Point
High/Low

1Day

52 Week

Valuation
Technical
Day's Volume

CASH

292.1 k

Shareholding (Mar 2025)

FII

8.33%

Held by 34 FIIs

DII

39.08%

Held by 22 DIIs

Promoter

34.86%

How big is Prelude Therapeutics, Inc.?

22-Jun-2025

As of Jun 18, Prelude Therapeutics, Inc. has a market capitalization of 52.37 million, with net sales of 7.00 million and a net profit of -127.83 million over the latest four quarters. The company reported shareholder's funds of 131.46 million and total assets of 175.51 million as of Dec 24.

Market Cap: As of Jun 18, Prelude Therapeutics, Inc. has a market capitalization of 52.37 million, categorizing it as a Micro Cap company.<BR><BR>Recent Quarterly Performance: For the latest four quarters, Prelude Therapeutics, Inc. reported net sales of 7.00 million and a net profit of -127.83 million.<BR><BR>Balance Sheet Snapshot: As of Dec 24, the company reported shareholder's funds of 131.46 million and total assets of 175.51 million.

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What does Prelude Therapeutics, Inc. do?

22-Jun-2025

Prelude Therapeutics, Inc. is a clinical-stage precision oncology company focused on developing small molecule therapies for cancer. It has a market cap of $52.37 million and reported a net profit loss of $32 million as of March 2025.

Overview:<BR>Prelude Therapeutics, Inc. is a clinical-stage precision oncology company focused on discovering and developing small molecule therapies optimized to target key driver mechanisms in cancers, operating within the Pharmaceuticals & Biotechnology industry and classified as a micro-cap company.<BR><BR>Financial Snapshot:<BR>Most recent Net Profit: -32 Million (Quarterly Results - Mar 2025)<BR>Market cap: USD 52.37 Million (Micro Cap)<BR><BR>Key Metrics:<BR>P/E: NA (Loss Making)<BR>Industry P/E: NA<BR>Dividend Yield: 0.00%<BR>Debt Equity: -0.93<BR>Return on Equity: -123.89%<BR>Price to Book: 0.51<BR><BR>Contact Details:<BR>Address: 200 Powder Mill Road, WILMINGTON DE: 19803<BR>Tel: 1 302 4671280<BR>Website: https://preludetx.com/

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Should I buy, sell or hold Prelude Therapeutics, Inc.?

22-Jun-2025

Who are in the management team of Prelude Therapeutics, Inc.?

22-Jun-2025

As of March 2022, the management team of Prelude Therapeutics, Inc. is led by Mr. Kris Vaddi, who is the Chief Executive Officer, Founder, and Director.

As of March 2022, the management team of Prelude Therapeutics, Inc. includes Mr. Kris Vaddi, who serves as the Chief Executive Officer, Founder, and Director.

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Is Prelude Therapeutics, Inc. overvalued or undervalued?

20-Sep-2025

As of November 6, 2024, Prelude Therapeutics, Inc. is considered risky and overvalued due to negative financial metrics, including a Price to Book Value of 0.56 and significant declines in stock performance compared to the S&P 500.

As of 6 November 2024, Prelude Therapeutics, Inc. has moved from a grade of does not qualify to risky. The company appears to be overvalued given its negative financial metrics and valuation ratios. The Price to Book Value stands at 0.56, the EV to EBIT is at 0.27, and the EV to EBITDA is at 0.28, indicating significant challenges in profitability and valuation relative to its assets.<BR><BR>In comparison to its peers, Prelude Therapeutics has a less favorable position; for instance, TriSalus Life Sciences, Inc. has a P/E ratio of -6.9780 and an EV to EBITDA of -8.5259, while Seer, Inc. has an EV to EBITDA of 1.1233. Prelude's negative returns are stark, with a year-to-date decline of -20.78% compared to the S&P 500's gain of 12.22%, and a one-year return of -58.61% against the S&P 500's 17.14%. These figures further reinforce the notion that the stock is overvalued in its current state.

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Is Prelude Therapeutics, Inc. technically bullish or bearish?

20-Sep-2025

As of September 8, 2025, Prelude Therapeutics, Inc. shows a mildly bullish trend supported by positive MACD and moving averages, despite mixed signals from Bollinger Bands and underperformance compared to the S&P 500.

As of 8 September 2025, the technical trend for Prelude Therapeutics, Inc. has changed from sideways to mildly bullish. The weekly MACD and KST indicators are both mildly bullish, while the monthly MACD is also mildly bullish, supporting a positive outlook. The daily moving averages are bullish, further reinforcing this stance. However, the monthly Bollinger Bands and KST are bearish, indicating some caution. The RSI shows a bullish signal on a monthly basis but no signal on the weekly. Overall, the indicators suggest a mildly bullish stance, albeit with some mixed signals.<BR><BR>In terms of performance, the stock has underperformed significantly compared to the S&P 500 across multiple periods, with a YTD return of -20.78% versus the S&P 500's 12.22%, and a 1Y return of -58.61% compared to 17.14% for the index.

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Strong Buy

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Dashboard
1

Positive results in Jun 25

  • NET PROFIT(HY) Higher at USD -63.32 MM
  • RAW MATERIAL COST(Y) Fallen by 0% (YoY)
  • NET SALES(9M) Higher at USD 4 MM
2

Risky - Negative EBITDA

3

High Institutional Holdings at 100%

4

Market Beating Performance

stock-summaryMojo Parameters
Mojo Parameters
Stock DNA
stock-summary
Industry

Pharmaceuticals & Biotechnology

stock-summary
Market cap

USD 71 Million (Micro Cap)

stock-summary
P/E

NA (Loss Making)

stock-summary
Industry P/E

NA

stock-summary
Dividend Yield

0.00%

stock-summary
Debt Equity

-0.93

stock-summary
Return on Equity

-163.93%

stock-summary
Price to Book

0.93

Revenue and Profits:
Net Sales:
(Quarterly Results - Jun 2025)
Net Profit:
-31 Million
stock-summaryTotal Returns
Total Returns (Price + Dividend) stock-summary
TimePeriod
Price Return
Dividend Return
Total Return
3 Months
26.23%
0%
26.23%
6 Months
64.65%
0%
64.65%
1 Year
56.87%
0%
56.87%
2 Years
-52.25%
0%
-52.25%
3 Years
-78.28%
0%
-78.28%
4 Years
-88.92%
0%
-88.92%
5 Years
-96.95%
0%
-96.95%

Prelude Therapeutics, Inc. for the last several years.

Risk Adjusted Returns v/s stock-summary
stock-summaryNews & Corporate Actions
News
Announcements stock-summary
Icon
No announcement available
Corporate Actions stock-summary
Icon
No corporate action available
stock-summaryKey Factors
Quality key factors stock-summary
Factor
Value
Sales Growth (5y)
51.57%
EBIT Growth (5y)
-209.00%
EBIT to Interest (avg)
-118.58
Debt to EBITDA (avg)
Negative Net Debt
Net Debt to Equity (avg)
-0.93
Sales to Capital Employed (avg)
0.06
Tax Ratio
0
Dividend Payout Ratio
0
Pledged Shares
0
Institutional Holding
100.00%
ROCE (avg)
0
ROE (avg)
0
Valuation key factors
Factor
Value
P/E Ratio
NA (Loss Making)
Industry P/E
Price to Book Value
0.56
EV to EBIT
0.27
EV to EBITDA
0.28
EV to Capital Employed
-5.66
EV to Sales
-5.47
PEG Ratio
NA
Dividend Yield
NA
ROCE (Latest)
Negative Capital Employed
ROE (Latest)
-123.89%
Technicals key factors
Indicator
Weekly
Monthly
MACD
Bullish
Mildly Bullish
RSI
Bearish
No Signal
Bollinger Bands
Mildly Bullish
Mildly Bearish
Moving Averages
Bullish (Daily)
KST
Bullish
Mildly Bullish
Dow Theory
Mildly Bullish
Mildly Bullish
OBV
No Trend
Bullish
stock-summary Technical Indicator Scale: Bearish, Mildly Bearish, Sideways, Mildly Bullish, Bullish  Turned 
stock-summaryShareholding
Shareholding Snapshot : Mar 2025stock-summary
Shareholding Compare (%holding) stock-summary
Majority shareholders

Strategic Entities

Domestic Funds

Held in 21 Schemes (17.72%)

Foreign Institutions

Held by 34 Foreign Institutions (8.33%)

Strategic Entities with highest holding

Highest Public shareholder

stock-summaryFinancial
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Quarterly Results Snapshot (Consolidated) - Jun'25 - YoYstock-summary
Jun'25
Jun'24
Change(%)
Net Sales
0.00
0.00
Operating Profit (PBDIT) excl Other Income
-31.80
-36.70
13.35%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-31.20
-34.70
10.09%
Operating Profit Margin (Excl OI)
0.00%
0.00%
NA
USD in Million.
Net Sales

YoY Growth in quarter ended Jun 2025 is 0.00% vs 0.00% in Jun 2024

Direction Arrows
Consolidated Net Profit

YoY Growth in quarter ended Jun 2025 is 10.09% vs -14.14% in Jun 2024

Annual Results Snapshot (Consolidated) - Dec'24stock-summary
Dec'24
Dec'23
Change(%)
Net Sales
7.00
0.00
Operating Profit (PBDIT) excl Other Income
-137.90
-131.10
-5.19%
Interest
0.00
0.00
Exceptional Items
0.00
0.00
Consolidate Net Profit
-127.20
-121.80
-4.43%
Operating Profit Margin (Excl OI)
-19,959.10%
0.00%
-1,995.91%
USD in Million.
Net Sales

YoY Growth in year ended Dec 2024 is 0.00% vs 0.00% in Dec 2023

Direction Arrows
Consolidated Net Profit

YoY Growth in year ended Dec 2024 is -4.43% vs -5.55% in Dec 2023

stock-summaryCompany CV
About Prelude Therapeutics, Inc. stock-summary
stock-summary
Prelude Therapeutics, Inc.
Pharmaceuticals & Biotechnology
Prelude Therapeutics Inc. is a clinical-stage precision oncology company. The Company is focused on discovering and developing small molecule therapies optimized to target the key driver mechanisms in cancers. Its drug discovery engine is designed to identify biological targets and create new chemical entities (NCEs). Its pipeline includes six programs including methyltransferases, kinases, protein-protein interactions and targeted protein degraders. It is developing therapies in both solid tumors and hematological malignancies such as adenoid cystic carcinoma (ACC), homologous recombination deficient positive (HRD+), cancers, myelofibrosis (MF) and glioblastoma multiforme (GBM), amongst others. The Company’s product candidates include PRT543, PRT811, PRT1419, SMARCA2, PRT2527 and PRT-K4.
Company Coordinates stock-summary
Company Details
200 Powder Mill Road , WILMINGTON DE : 19803
stock-summary
Tel: 1 302 4671280
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Registrar Details